Bioreducible disulfide linkage-employing drug conjugate has already been approved for drug delivery application, and also has shown immense potential in gene and siRNA transfection. This paper will focus on the recent developments in bioreducible polymeric systems for gene and siRNA delivery application, and will discuss the advantages and challenges associated with reducible polymeric carriers.
Review Biomedical materials (Bristol, England). 2009 Apr;4(2):025020. doi: 10.1088/1748-6041/4/2/025020 Q23.72025
Bioreducible polymers for efficient gene and siRNA delivery
高效基因和siRNA递送的可降解聚合物 翻译改进
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DOI: 10.1088/1748-6041/4/2/025020 PMID: 19349651
摘要 Ai翻译
Keywords：bioreducible polymers; gene delivery; sirna delivery
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