Antibiotic release from keratin hydrogels for use in wound healing applications [0.03%]
角蛋白水凝胶的抗生素缓释性能及其伤口愈合应用研究
Rachael Simmons,Seth Tomblyn,Luke Burnett et al.
Rachael Simmons et al.
Skin injuries, particularly severe injuries, such as full-thickness wounds or surgical sites, are susceptible to bacterial infection. Materials composed of keratin proteins have been investigated for use in wound dressings, and at least two...
Muhammad Rizwan,Xuan Mei,Ling Cai et al.
Muhammad Rizwan et al.
The development of effective treatment strategies against head and neck cancer (HNC) poses a significant challenge due to the heterogeneity of HNC and the limitations of traditional two-dimensional (2D)in vitrocell cultures. Consequently, t...
Reactive oxygen species-functionalized hydrogels loaded with ginger-derived nanoparticles promote diabetic wound healing by modulating macrophage polarization [0.03%]
基于姜提取物的纳米粒子的功能化活性氧凝胶通过调节巨噬细胞极化促进糖尿病伤口愈合
Xinxin Geng,Dazhi Ke,Qinyi Xu et al.
Xinxin Geng et al.

Purpose: Diabetic cutaneous injuries frequently exhibit prolonged inflammatory responses and excessive accumulation of reactive oxygen species (ROS), which collectively impede normal healing cascades. Standard therapeutic approaches of...
Harnessing dual gradients of topography and mineralization via a modified electrospinning strategy in polyacrylonitrile/MWCNT nanofibrous membranes for enhanced osteogenic differentiation [0.03%]
通过改进的电纺丝策略在聚丙烯睛/多壁碳纳米管纳米纤维膜中利用地形和矿化的双重梯度促进成骨分化
Subin Park,Jeong In Kim,Soonchul Lee
Subin Park
The rational design of bone-regenerative scaffolds requires precise control over nano-to microscale architecture and biomineralization kinetics. Here, we report a modified electrospinning strategy to fabricate PAN/MWCNT nanofibrous scaffold...
Hemostatic and antibacterial performance of alginate/tannic acid-coated gauze for advanced wound care [0.03%]
用于先进伤口护理的藻酸盐/单宁酸包覆纱布的止血和抗菌性能
Sun Min Hwang,Yu Jin Jeong,Jun Tae Kim et al.
Sun Min Hwang et al.
Medical cotton gauze has traditionally been used as a local hemostatic material. However, there is a growing demand for innovative solutions that not only reduce blood loss but also prevent secondary infections. In the present study, a nove...
A sequentially orthogonal dual-peptide (TPS/DGEA) coating with synergistic anticoagulant, anti-inflammatory and pro-endothelialization functions for vascular stents [0.03%]
一种具有序贯正交双肽(TPS/DGEA)涂层的血管支架的协同抗凝、抗炎和促内皮化功能
Huaishi Chen,Qihao Bian,Xinyu Pei et al.
Huaishi Chen et al.
Drug-eluting stents (DES) effectively reduce restenosis but are hampered by delayed re-endothelialization and chronic inflammation, which can trigger late thrombosis. Addressing this requires a surface that simultaneously promotes rapid end...
Restoration of ampicillin susceptibility in drug-resistant enterococcus faecalis via synergistic therapy with co-functionalized gold nanoparticles [0.03%]
协同功能化金纳米颗粒联合疗法恢复耐药肠球菌的氨苄西林敏感性
Qingqing Li,Mingzhi Huang,Peng Wang
Qingqing Li
Enterococcus faecalis (E. faecalis), a leading pathogen associated with severe nosocomial infections, poses a major control challenge owing to its widespread multidrug resistance. Current first-line therapies for E. faecalis infections comb...
A review on assessment of advances in polymers and their hybrid nanosystem for leukaemia theranostics applications [0.03%]
用于白血病诊疗的聚合物及其杂化纳米系统评估进展综述
Soni Prajapati,Akash Kumar,Ranjana Singh
Soni Prajapati
Leukaemia, a widespread haematological cancer, possesses particular challenges in theranostics despite the availability of traditional and modern approaches. This article addresses a significant gap in the literature, where a focus on polym...
Controllable preparation of magnesium-hybridized PLA-PEG-PLA porous microspheres with anti-inflammatory function [0.03%]
具有抗炎功能的可调控镁杂化PLA-PEG-PLA多孔微球的制备
Xu Liu,Ziyang Yuan,Dong Zhou et al.
Xu Liu et al.
Biodegradable polylactic acid-based microspheres have been widely used in biomedical applications such as drug delivery and tissue engineering, however, most of the microspheres typically possess simple surface structures, lacking bioactivi...
Core-shell fibrous threads loaded with VEGF plasmid polyplexes for sustained, threshold-guided gene delivery [0.03%]
负载VEGF质粒聚复合物的核壳纤维线用于持续、阈值指导的基因输送
Farzaneh Ghasemkhah,Masoud Latifi,Afra Hadjizadeh et al.
Farzaneh Ghasemkhah et al.
Precise regulation of vascular endothelial growth factor (VEGF) delivery is essential for angiogenesis-oriented tissue engineering, because excessive or poorly controlled VEGF exposure may lead to abnormal and immature vascular structures. ...