Optimizing the Dosing of Heparin for Therapeutic Anticoagulation in Neurocritical Care Patients at High Risk of Bleeding: Report on a Quality Improvement Initiative [0.03%]
神经重症出血高风险患者治疗性抗凝用肝素剂量优化质量改进报告
Sahil Kapoor,Nick Scaturo,Garrett Thompson et al.
Sahil Kapoor et al.
Background: Heparin infusions are used to treat and prevent thromboembolic complications in neurocritical care, but optimal dosing in patients with acute intracranial pathology or recent neurosurgery is uncertain, due to elevated risk of he...
Changes in Glucagon-Like Peptide-1 Receptor Agonist (GLP-1 RA) Exposures Following Recent Demand for Weight Management: A Retrospective Review of California Poison Control System Data [0.03%]
加州毒物控制系统的回顾性数据分析：近期减肥需求增加后，胰高血糖素样肽-1受体激动剂（GLP-1RA）暴露的变化
Raymond Y Ho,Hsiaoting Regelman,Anita Ma et al.
Raymond Y Ho et al.
Background: Calls to poison centers involving exposure to glucagon-like peptide-1 receptor agonists (GLP-1 RA) have increased. Data from a statewide poison control system from 2017 to 2023 was analyzed to assess changes in GLP-1 RA exposure...
Eligibility for Intramuscular Cabotegravir/Rilpivirine in HIV-Positive Patients: An Observational Study [0.03%]
关于HIV阳性患者接受肌内注射卡博特格拉韦/利匹韦林的资格：一项观察性研究
Gabriel Martínez-Orea,Francisco José Rodríguez-Lucena,Francisca Fuentes-Hidalgo et al.
Gabriel Martínez-Orea et al.
Background: HIV treatment has advanced significantly with the introduction of simpler antiretroviral regimens, but adherence remains a challenge. In this context, the long-acting injectable combination cabotegravir/rilpivirine (CAB/RPV) eme...
Salvage Therapy With a Triple Combination of Daptomycin, Carbapenem, and Oxazolidinone in Patients With Persistent MRSA Bacteremia of Cardiovascular Focus: A Case Series [0.03%]
达托霉素、碳青霉烯类和恶唑烷酮三联挽救治疗心血管病灶耐甲氧西林金黄色葡萄球菌持续性血流感染：病例系列研究
Kotaro Mitsutake,Natsuki Shinya,Haruka Karaushi et al.
Kotaro Mitsutake et al.
Prophylactic Enoxaparin Dosing and Anti-Xa Levels in Medicine Patients With Obesity [0.03%]
肥胖内科患者的预防性低分子肝素用药及抗因子Xa水平研究
Wint War Phyo,Karishma Deodhar,Amy Chang et al.
Wint War Phyo et al.
Introduction: Previous studies have shown that the manufacturer's standard fixed dosing of enoxaparin for venous thromboembolism (VTE) prophylaxis leads to sub-prophylactic anti-Xa levels in medicine patients with obesity. Yet, there is lim...
Comparing the Safety and Effectiveness of Apixaban Lead-In Dosing Strategies in Hospitalized Adults With Venous Thromboembolism [0.03%]
比对阿哌沙班初始剂量法在静脉血栓栓塞住院成人中的安全性和有效性
Juliana Spencer,Tanner Buchanan,Samantha Heacock et al.
Juliana Spencer et al.
Background: Clinicians often use parenteral lead-in regimens prior to direct oral anticoagulants (DOACs) for venous thromboembolism (VTE) in hospitalized patients due to shorter half-life and the ability to use laboratory monitoring. Object...
Standard Instructions and Counseling for Naloxone Insufficient in the Era of Xylazine and Medetomidine Adulteration of Illicit Opioids [0.03%]
在非法阿片类药物中添加了戊唑仑和美达托明的时代，纳洛酮的标准指导说明和咨询是不够的
Priya Datta,Kristin Waters,C Michael White
Priya Datta
Impact of Hybrid Care in Pharmacist-Led Diabetes Clinics on Hemoglobin A1c [0.03%]
药师主导的糖尿病诊所中混合护理对糖化血红蛋白的影响
Ashley E Smith,Jacqueline Burke,Devan Hawkins et al.
Ashley E Smith et al.
Background: During the coronavirus disease 2019 (COVID-19) pandemic, many clinical practices shifted to using virtual platforms to care for patients. After in-person visits resumed, many patients continued to participate in virtual care. Ob...
Fabiana Schuelter-Trevisol,Francieli Cipriano Felippe,Bruna Camargo et al.
Fabiana Schuelter-Trevisol et al.
Study objectives: Zolpidem is a widely prescribed medication for treating insomnia due to its effectiveness as a sedative-hypnotic. This study aimed to estimate the incidence of potential adverse effects associated with t...
Thiamine and Ascorbic Acid in Sepsis and Septic Shock: A Review of Evidence for their Role in Practice [0.03%]
脓毒症和脓毒性休克中的维生素B1和抗坏血酸：对其在临床实践中作用的证据进行综述
Justin P Reinert,Kegan Becker,Martin J Ohlinger
Justin P Reinert
Objective: To evaluate the evidence for the use of ascorbic acid, thiamine, or a combination of both agents without corticosteroids in the management of sepsis and septic shock. ...