Evaluation of Neuropsychiatric Events in Patients Receiving Levetiracetam for Seizure Prophylaxis Following Traumatic Brain Injury [0.03%]
Matthew J Ammoscato,Aubrey N Evers,Jacob R Partington et al.
Matthew J Ammoscato et al.
Background: Levetiracetam is a soluble ethyl analogue of the nootropic agent piracetam that is utilized primarily for epilepsy treatment. Studies have shown levetiracetam has preferred pharmacokinetic and pharmacodynamic properties compared...
Association Between a Shortage of Normal Saline and In-Hospital Outcomes Among Individuals With Febrile Neutropenia [0.03%]
Allie E Stacks,Logan A Russell,Erin R Weeda
Allie E Stacks
Background: Normal saline (NS) is a vital resource used to care for patients with febrile neutropenia (FN). A 2017 shortage in NS driven by Hurricane Maria raised concerns about patient outcomes. Objective: This study aimed to evaluate the ...
Cyclobenzaprine Reimagined: Clinical Insights Into Tonmya for Fibromyalgia [0.03%]
环苯扎林新用——托恩迈亚治疗纤维肌痛的临床洞见
Erin St Onge,Phuoc Tyler Bui,Haven Rogers et al.
Erin St Onge et al.
Objective: To review the efficacy, safety, and tolerability of a sublingual formulation of cyclobenzaprine for the treatment of fibromyalgia. Data Sources: A literature search was conducted through PubMed and DrugBank using the following te...
Acute Pancreatitis Associated with Propofol in a Patient with End-Stage Renal Disease: Diagnostic Challenges and Confounding Factors [0.03%]
终末期肾病患者与丙泊酚相关的急性胰腺炎：诊断难题及混杂因素
Waldo-Rodríguez Itzayana Guadalupe,Arriaga-García Francisco Javier,Romano-Moreno Silvia et al.
Waldo-Rodríguez Itzayana Guadalupe et al.
Objective: Acute pancreatitis is an inflammatory disorder of the pancreas with diverse etiologies, including rare drug-induced causes such as propofol. Propofol-associated acute pancreatitis has been linked to hypertriglyceridemia; however,...
Vancomycin Overdose and Infusion Rate Error Leading to a Mixed Anticholinergic-Type Syndrome in a Hemodialysis Patient: A Case Report [0.03%]
一例维持性血液透析患者万古霉素中毒合并输注浓度过高导致的混合型抗胆碱能综合征：病例报告
Waldo-Rodríguez Itzayana Guadalupe,Arriaga-García Francisco Javier,Romano-Moreno Silvia et al.
Waldo-Rodríguez Itzayana Guadalupe et al.
Objective: To describe a mixed anticholinergic-type syndrome not previously associated with vancomycin in a patient with end-stage renal disease on hemodialysis, highlighting the impact of dosing and infusion rate errors. Case: A 61-year-ol...
Stevens-Johnson Syndrome And Toxic Epidermal Necrolysis Possibly Related to Daptomycin And Ceftaroline in a Patient With Persistent Methicillin-Resistant Staphylococcus aureus Bacteremia: A Case Report and Brief Review [0.03%]
万古霉素耐药的金黄色葡萄球菌败血症患者使用达托霉素和_ceftaroline_导致重症药物反应(stevens-johnson综合征和毒性表皮坏死松解症)的病例报告及简要述评
Nardine Karam Salgado,Jaina Patel,Stanley Moy
Nardine Karam Salgado
Objective: We report a unique case of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) possibly related to administering daptomycin and ceftaroline for persistent methicillin-resistant Staphylococcus aureus (MRSA) bactere...
Overview of Diabetes Medications: Traditional and New-Generation Agents and Their Off-Label Use for Weight Loss [0.03%]
糖尿病药物概览：传统及新一代药物及其非适应证减重应用
Eleonora Castellana,Patricia Madalina Budau,Maria Rachele Chiappetta
Eleonora Castellana
Objective: Diabetes mellitus encompasses chronic metabolic disorders marked by impaired insulin secretion, action, or both, with type 1 and type 2 diabetes presenting distinct mechanisms and therapeutic needs. Achieving durable glycemic con...
Restriction Evaluation of Appropriate Carbapenem Therapy (REACT): A Multisite Observational Study [0.03%]
适当卡巴 penem 治疗的限制评估（ REACT）：一项多中心观察性研究
Drew A Wells,Madison McKnight,Jessica Jaggar et al.
Drew A Wells et al.
Introduction: Overuse of carbapenem antibiotics can lead to patient harm through adverse effects and further development of bacterial resistance. The purpose of this study was to investigate the sustained impact of meropenem restriction cri...
Brandon J Skory,John Arko,Laila Terkawi et al.
Brandon J Skory et al.
Background: Beta blockers are no longer recommended as first-line agents for hypertension (HTN) without compelling indications; however, evidence suggests that there is still frequent inappropriate prescribing of beta blockers to many US ad...
Maintaining Growth Hormone Therapy Adherence During Shortages: The Role of Specialty Pharmacy [0.03%]
短缺期间特药维持生长激素治疗的依从性作用
Julie MacDougall,Heather Cournoyer
Julie MacDougall