Evaluation of Gabapentin and Pregabalin Use in Hospitalized Patients With Decreased Kidney Function [0.03%]
加巴喷丁和普瑞博林在肾功能降低的住院患者中使用的安全性评估
Gwendolyn M Knowles,Grace E LaFleur,Mariann D Churchwell
Gwendolyn M Knowles
Background: Gabapentin and pregabalin are well-tolerated medications primarily cleared by the kidney. Patients receiving higher gabapentinoid doses with decreased kidney function may be at an increased risk of adverse effects (AEs), but lim...
Implementation and Evaluation of Weight-Based Vasopressors in Intensive Care Units [0.03%]
重症监护病房中基于体重的血管加压素的实施和评估
Laurie DeMillard,Michael Thuyns
Laurie DeMillard
Background: Vasopressors, including norepinephrine, epinephrine, and phenylephrine are commonly used to maintain mean arterial pressure (MAP) in critically ill patients. Despite their frequent use, the optimal dosing strategy for vasopresso...
Hakeam A Hakeam,Khadija A Sarkhi,Alla Iansavichene
Hakeam A Hakeam
Objective: To describe the clinical characteristics of hypoglycemia that develop with tigecycline therapy and to review and summarize the current evidence of this uncommonly occurring metabolic adverse effect of tigecycline therapy. Underly...
Drug Utilization Evaluation Study of Ciprofloxacin Use and Adverse Events Occurrence: Role of Community Pharmacists [0.03%]
左氧氟沙星使用和不良事件发生率的药物评价研究：社区药师的作用
Gaidaa M Dogheim,Rehab H Werida
Gaidaa M Dogheim
Background: Antimicrobial resistance is a global health crisis threatening optimal management of infectious diseases. Ciprofloxacin is a widely used fluoroquinolone in various disease conditions. Resistance against ciprofloxacin is increasi...
Demonstrating the Benefits of Antihypertensive Nighttime Dosing and Indapamide Usage in Hypertension Management [0.03%]
在高血压管理中展示降压药夜间服用和吲达帕胺使用的益处
Jonathan S Newsome
Jonathan S Newsome
Background: Uncontrolled hypertension, specifically nocturnal hypertension, increases the risk for significant clinical outcomes. Evidence on the use of nighttime antihypertensives is scant and conflicting. In addition, hydrochlorothiazide ...
Examining an Interaction Between Plasma Exchange and Apixaban Resulting in an Acute Ischemic Stroke [0.03%]
血浆置换和阿哌沙班之间相互作用导致急性缺血性卒中的分析
Katlyn Holt,Katelyn Dulgar,Justin P Reinert
Katlyn Holt
Objective: Therapeutic drug monitoring is not routinely considered necessary in patients undergoing plasma exchange; however, it is possible for serum concentrations of select medications to be impacted by this procedure. Case: We describe ...
Dalbavancin Use in Persons Who Use Drugs May Increase Adherence Without Increasing Cost [0.03%]
在药物使用者中使用 Dalbavancin 可能会提高依从性而不增加成本
Tiffany A Russo,Hannah R Ritchie,Jennifer J Schimmel et al.
Tiffany A Russo et al.
Background: Dalbavancin (DAL) may obviate concerns regarding misuse of IV access in persons who use drugs (PWUD) completing treatment for infections in an outpatient setting. However, hesitancy to adopt its use exists due to the cost-prohib...
Integrating Software Into Hospital Quality Structures: What Practices Do Pharmaceutical Inspector Co-Operation Scheme (PIC/S) Guidelines Recommend? [0.03%]
将软件整合到医院质量结构中：药品监察合作计划(PIC/S)指南推荐哪些做法？
Fabiana Scione,Khaled Yousef Abdelmaula,Dustin Balzan et al.
Fabiana Scione et al.
Updated Review Article: Cyclin-Dependent Kinase 4/6 Inhibitor Impact, FDA Approval, and Resistance Pathways [0.03%]
更新综述文章：细胞周期蛋白依赖性激酶4/6抑制剂的作用、FDA批准及耐药机制
Rodney J Hunter,Jooyoung Park,Kristen J Asprer et al.
Rodney J Hunter et al.
Objective: To describe the mechanism of cyclin-dependent kinase (CDK) 4/6 inhibitors, mechanisms of resistance, and summarize various clinical trials used to determine the efficacy and safety of CDK4/6 inhibitor used for the treatment of ho...
Evaluating the Impact of Pharmacist Dual Verification of Anticancer Therapy in the Modern Era [0.03%]
评估 pharmacist 双重校验对现代抗癌治疗的影响
Devon S Stonerock,Kaylee Clark,Vishal Shah et al.
Devon S Stonerock et al.
Background: Pharmacist order verification is a critical step in ensuring medication safety for patients. While the second pharmacist verification (SPV) before dispensing anticancer therapies has been a longstanding practice, its continued n...