Ultrasound imaging and regulated mechanotransduction for characteristics, regeneration, and therapeutics of bone [0.03%]
超声成像和力学信号转导在骨的特性、再生及治疗中的作用
Yi-Xian Qin
Yi-Xian Qin
Ultrasound imaging has been widely used in clinical diagnoses, such as B-mode and M-mode ultrasound imaging for cardiovascular, abdomen, OB-Gyn, and other soft tissue and organs in clinical diagnoses. Ultrasound imaging has traditionally be...
Matrix stiffness and viscoelasticity influence human mesenchymal stem cell immunomodulation [0.03%]
基质刚度和黏弹性对人 mesenchymal干细胞免疫调节影响
Sara J Olsen,Rose E Leader,Abigail L Mortimer et al.
Sara J Olsen et al.
Human mesenchymal stem cells (hMSCs) have immense wound healing potential due to their immunomodulatory behavior. To control this behavior and reduce heterogeneity, researchers look to biomaterials, as matrix stiffness and viscoelasticity h...
Minyu Chen,Guoqiang Li
Minyu Chen
ChatGPT has garnered significant attention for its impressive capabilities across various domains, including medicine and mechanobiology. In order to facilitate the integration of ChatGPT into research, this paper explores the applications ...
Improvement of hemodynamics in mesenteric microcirculation in septic shock rats by anisodamine and anisodine [0.03%]
阿托品甲氧基 norscopolamine 和阿托品类生物碱改善感染性休克大鼠肠系膜微循环功能的作用比较研究
Jian Zhong,Zhi Ouyang,Junyi Shen et al.
Jian Zhong et al.
Anisodamine and anisodine have been used in treatment of septic shock, but the underlying mechanism are still unclear. In the present study, the effects of anisodamine hydrobromide (Ani HBr) and anisodine hydrobromide (AT3) on the mesenteri...
Jian Shou,Yunlong Huo
Jian Shou
Dysfunctions of calcium cycling occur in heart failure with reduced and preserved ejection fraction (HFrEF and HFpEF). HFrEF and HFpEF showed Ca2+ leakage at diastole. The compensation of Na+/Ca2+ exchanger and the decrease of T-tubule dens...
Fabrication of 3D matrix microenvironment by two-photon lithography for mechanobiology study [0.03%]
利用双光子光刻技术制备三维基质微环境用于力学刺激研究
Zuyan Lu,Wenbo Jiang,Weixin Zhao et al.
Zuyan Lu et al.
Mechanobiology is the study of how mechanical forces affect biological systems, including cells and tissues. The two-photon lithography (TPL) as a powerful 3D printing technique allows the creation of 3D complex structures at a microscopic ...
Shu Chien
Shu Chien
Zong-Lai Jiang
Zong-Lai Jiang
Mechanobiology is an interdisciplinary discipline combining biology, engineering, chemistry, physics, and medicine. Mechanobiology research comprehensively discusses, the role of mechanical factors in various life processes and the occurren...
The application of ECM-derived biomaterials in cartilage tissue engineering [0.03%]
ECM衍生物在软骨组织工程中的应用研究进展
Yu-Wei Wang,Ming-Ze Du,Tuo Wu et al.
Yu-Wei Wang et al.
Given the tremendous increase in the risks of cartilage defects in the sports and aging population, current treatments are limited, and new repair strategies are needed. Cartilage tissue engineering (CTE) is a promising approach to handle t...
Platelet-derived microvesicles drive vascular smooth muscle cell migration via forming podosomes and promoting matrix metalloproteinase-9 activity [0.03%]
血小板微囊通过形成盘状伪足和促进基质金属蛋白酶-9活性来驱动血管平滑肌细胞迁移
He Ren,Jiahe Chen,Kai Huang et al.
He Ren et al.
We have shown that platelet-derived microvesicles (PMVs) induce abnormal proliferation, migration, and energy metabolism of vascular smooth muscle cells (VSMCs) after vascular intimal injury. Here, we examined a novel role of podosome in me...