Distribution of intracellular calcium during flow-induced migration of RAW264.7 cells [0.03%]
流动刺激下RAW264.7细胞迁移过程中的胞内钙离子分布规律研究
Shurong Wang,Qing Sun,Yang Zhao et al.
Shurong Wang et al.
Cell migration is an important biological process regulated by mechanical stimulation, which leads to intracellular calcium response. Cell migration are dependent on the distribution and dynamic changes of intracellular calcium concentratio...
Cell mechanics in early vertebrate development: Yap mechanotransduction controls notochord formation and neural tube patterning [0.03%]
脊椎动物早期发育的细胞力学：Yap机械信号转导控制软骨发育和神经管图案化
Zheng Guo,Jing Du
Zheng Guo
A recent study published in Science Advances 1 showed the influence of Yap on notochord formation and NT (neural tube) patterning in vertebrate embryonic development, and conducted an in-depth study from the perspective of biomechanical sig...
Osteoinductive intramedullary implant as an adjunctive therapy for bone transport: A promising approach to accelerate bone defect healing [0.03%]
一种促进成骨的髓内植入物作为骨运输的辅助治疗：加速骨缺损愈合的一种有前途的方法
Yuejun Lin,Jiaming Yang,Gang Li
Yuejun Lin
A recent study published in Nature Communications presents a unique approach using an osteoinductive intramedullary (IM) implant as an adjunctive therapy for bone transport distraction osteogenesis. The study demonstrates that this innovati...
Valeria Panzetta,Claudia De Clemente,Michele Russo et al.
Valeria Panzetta et al.
The mechanical microenvironment strongly affects cell state and decisions. Cell mechanosensing has been described by a molecular clutch which gets progressively engaged depending upon the stiffness of the extracellular material. Through the...
Angiogenesis within atherosclerotic plaques: Mechanical regulation, molecular mechanism and clinical diagnosis [0.03%]
动脉粥样硬化斑块内血管生成：力学调控、分子机制及临床诊断
Hanxiao Chen,Chengxiu Peng,Fei Fang et al.
Hanxiao Chen et al.
Atherosclerosis (AS) is a disease characterized by focal cholesterol accumulation and insoluble inflammation in arterial intima, leading to the formation of an atherosclerotic plaque consisting of lipids, cells, and fibrous matrix. The pres...
Mechanotransduction and inflammation: An updated comprehensive representation [0.03%]
力学信号转导与炎症：综合更新表示法
Vennila Suriyagandhi,Ying Ma,Veronica Paparozzi et al.
Vennila Suriyagandhi et al.
Mechanotransduction is the process that enables the conversion of mechanical cues into biochemical signaling. While all our cells are well known to be sensitive to such stimuli, the details of the systemic interaction between mechanical inp...
Relationship between bilateral symmetry of foot posture and lower limb musculoskeletal injuries among workers engaged in physically demanding occupations: A cross-sectional investigation [0.03%]
体力劳动者足部姿势的双侧对称性与下肢运动损伤之间的关系：一项横断面调查研究
Chunhua Liao,Jing Liu,Shuanglong Hou et al.
Chunhua Liao et al.
Even though the link between foot posture and lower-extremity injuries remains controversial, there has been little research focus on bilateral foot symmetry. This study evaluated the correlation between bilateral symmetry in foot posture a...
Mechanotransductive N-cadherin binding induces differentiation in human neural stem cells [0.03%]
机械转导N-钙粘蛋白结合诱导人类神经干细胞分化
McKay Cavanaugh,Rebecca Kuntz Willits
McKay Cavanaugh
The neural stem cell niche is a complex microenvironment that includes cellular factors, secreted factors, and physical factors that impact stem cell behavior and development. Cellular interactions through cadherins, cell-cell binding prote...
Toward a clear relationship between mechanical signals and bone adaptation [0.03%]
面向机械信号与骨适应之间关系的澄清研究
Chenlu Wang,Ruisen Fu,Haisheng Yang
Chenlu Wang
Bone adapts according to the mechanical environment, and this adaptation can be visualized by altering its shape, size, and microarchitecture. Bone adaptation was recognized more than a century ago, with a description presented in The Law o...
Mechanobiological cues to bone cells during early metastasis drive later osteolysis: A computational mechanoregulation framework prediction [0.03%]
骨细胞在早期转移期间的力学生物学信号促进晚期溶骨：计算力学调控框架预测
Anneke S K Verbruggen,Elan C McCarthy,Roisin M Dwyer et al.
Anneke S K Verbruggen et al.
Bone cells contribute to tumour metastasis by producing biochemical factors that stimulate tumour cell homing and proliferation, but also by resorbing bone matrix (osteolysis) that releases further stimulatory factors for tumour growth in a...