Single-cell omics in plant biology: mechanistic insights and applications for crop improvement [0.03%]
单细胞组学在植物生物学中的应用：机制洞察及作物改良展望
Tao Zhu,Tianxiang Li,Peitao Lü et al.
Tao Zhu et al.
In recent years, single-cell omics technologies have significantly advanced plant and agricultural research, providing transformative insights into plant development, cellular heterogeneity, and environmental response mechanisms. Traditiona...
Microalgae-driven microrobots: revolutionizing drug delivery and targeted therapy in biopharmaceuticals [0.03%]
微藻驱动的微型机器人：生物医药中的药物递送和靶向治疗革命
Xianmin Wang,Songlin Ma,Renwu Liu et al.
Xianmin Wang et al.
Microalgae are a group of photosynthetic autotrophic microorganisms that are classified as Generally Recognized as safe (GRAS). They are rich in high-value bioactive compounds with broad applications in food, healthcare and pharmaceuticals....
Yinling Qushi Granule as a therapeutic agent for metabolic syndrome: pharmacological, molecular targets, and pharmacokinetic insights [0.03%]
阴凌毓秀颗粒治疗代谢综合征的疗效、分子靶点及药代动力学研究见解
Linlin Jin,Shaoqin Lin,Yan He et al.
Linlin Jin et al.
Metabolic Syndrome (MetS) is a globally prevalent condition with unclear underlying mechanisms. Current treatments primarily focus on alleviating individual symptoms, lacking long-term therapeutic strategies that target the disease's endoty...
Assembly and analysis of Sinipercidae fish sex chromosomes reveals that a supergene drives sex chromosome origin and turnover [0.03%]
鲤科鱼类性染色体的组装与分析揭示了一个超基因驱动性染色体的起源和转换
Chong Han,Shiyan Liu,Suhan Peng et al.
Chong Han et al.
The sex chromosomes of fish are usually homomorphic and recently derived, making them an ideal model to understand the origin and evolution of sex chromosomes in vertebrates. Here, combined Pacbio, Hi-C, and Illumina sequencing of the male ...
Development of a versatile synthetic microbe for the concurrent degradation of organic pollutants [0.03%]
一种用于同时降解有机污染物的多功能合成微生物的发展研究
Cong Su,Shuangying Jiang,Junbiao Dai
Cong Su
Excavation of acoustic nanostructures biosynthesis gene clusters by combinatorial strategy [0.03%]
基于组合策略挖掘声学纳米结构生物合成基因簇
Wei Liu,Tingting Liu,Shenxi Huang et al.
Wei Liu et al.
Gas vesicles (GVs) produced by microorganisms are genetically engineered, air-filled protein nanostructures that have widespread applications in ultrasound imaging and ultrasound-mediated drug delivery. However, constrained by the shape and...
Advances in silica nanoparticles for agricultural applications and biosynthesis [0.03%]
用于农业应用和生物合成的二氧化硅纳米颗粒研究进展
Fei Li,Yuxi Hou,Lu Chen et al.
Fei Li et al.
Nanotechnology has emerged as a revolutionary force in modern agriculture, opening new avenues for crop enhancement and sustainable farming practices. This review systematically evaluates the roles of silica nanoparticles (SiO2 NPs) in agri...
Pathogenic profiles and lower respiratory tract microbiota in severe pneumonia patients using metagenomic next-generation sequencing [0.03%]
应用宏基因组高通量测序技术分析重度肺炎患者病原菌特征及下呼吸道微生态变化
Xinjie Han,Peng Ma,Chang Liu et al.
Xinjie Han et al.
Introduction: The homeostatic balance of the lung microbiota is important for the maintenance of normal physiological function of the lung, but its role in pathological processes such as severe pneumonia is poorly underst...
Nepenthes chitinase NkChit2b- 1 confers broad-spectrum resistance to chitin-containing pathogens and insects in plants [0.03%]
耐宾thes NkChit2b- 1 蛉虫凝聚素赋予植物广谱的抗真菌和抗昆虫特性
Jun-Jie Liu,Jin-Xuan Wen,Jian-Feng Li et al.
Jun-Jie Liu et al.
Chitinases play critical roles in plant-pathogen/insect interactions by degrading chitin, a key structural component of fungal cell walls and insect exoskeletons. However, current research lacks comprehensive studies on the broad-spectrum d...
Harnessing RNA base editing for diverse applications in RNA biology and RNA therapeutics [0.03%]
利用RNA碱基编辑在RNA生物学和RNA疗法中的多种应用
Hui Luo,Jing Yao,Rui Zhang
Hui Luo
Recent advancements in molecular engineering have established RNA-based technologies as powerful tools for both fundamental research and translational applications. Among the various RNA-based technologies developed, RNA base editing has re...