From detection to action: artificial intelligence in integrated pest and invasive plant management [0.03%]
从检测到行动：人工智能在综合病虫害和入侵植物管理中的应用
Yaoxing Li,Lianming Zha,Weitong Liu et al.
Yaoxing Li et al.
Global agriculture faces growing threats from pests, pathogens, and invasive species, intensified by climate change and biodiversity losses. Conventional approaches are limited in both precision and scale, and artificial intelligence (AI) i...
Bio-effects of engineering nanomaterials NiFe-based LDHs on ryegrass-soil system [0.03%]
工程纳米材料NiFe-LDHs对土壤-黑麦草体系的生物效应研究
Haocheng Xu,Xiaoqian Jiang,Chuntao He et al.
Haocheng Xu et al.
NiFe-based layered double hydroxides (LDHs), as engineered nanomaterials (ENMs), are widely utilized in industrial applications, environmental remediation, and soil improvement. However, the biological impacts of such ENMs on plant-soil sys...
SPAID: a comprehensive database for disease-specific autoantigens in autoimmune disorders [0.03%]
SPAID数据库：自身免疫性疾病特异性自身抗原的全面库藏资源
Shunhui Deng,Fangfang Wei,Ya Pang et al.
Shunhui Deng et al.
Autoimmune diseases (ADs) are chronic inflammatory disorders characterized by complex etiologies and significant diagnostic challenges. Although autoantigens are critical for precision diagnosis and therapy, much of the immunogenic landscap...
Controllable nanotopography of lysine-branched self-assembling peptide hydrogels for tendon-bone insertion regeneration [0.03%]
用于肌腱骨结合再生的赖氨酸分支自组装肽水凝胶纳米拓扑结构的可控性
Xu Liu,Chenyu Wang,Xiao Zhao et al.
Xu Liu et al.
Recent advances in tissue engineering have highlighted the critical roles of both mechanical and biochemical characteristics in tendon-bone insertion (TBI) regeneration. However, the influence of surface topography, particularly the develop...
Phagocytotic impairment of tissue-resident alveolar macrophages by diesel particulates drives pulmonary surfactant accumulation [0.03%]
柴油颗粒物对组织驻留肺泡巨噬细胞的吞噬功能障碍导致肺表面活性物质聚集
Ruiqi Chen,Zhenkun Zhou,Jing Wang et al.
Ruiqi Chen et al.
Airborne particulate matter, particularly diesel particulate matter (DPM), is a major component of air pollution and poses significant risks to lung health. Tissue-resident alveolar macrophages (TR-AMs), which dominate the immune landscape ...
Base editing of Artemis mutations ex vivo sheds light on gene therapy for Artemis-deficient SCID [0.03%]
体外编辑ART缺陷型重症联合免疫缺陷症相关的ARTEMIS突变以期用于基因治疗
Ziwen Huang,Zhenxi Cai,Peiyang Yan et al.
Ziwen Huang et al.
Artemis is an endonuclease that cleaves DNA hairpins during V(D)J recombination, a critical step enabling coding-joint formation and essential for lymphocyte development. Artemis-deficient severe combined immunodeficiency (ART-SCID) is a mo...
Design and validation of a ribosome display library for synthetic nanobody selection [0.03%]
合成纳米抗体筛选的核糖体显示文库的设计与验证
Weijie Gu,Yaning Li,Jingjing Hong et al.
Weijie Gu et al.
Single-domain antibodies (nanobodies) are compact, highly engineerable binding scaffolds widely used in structural biology, biotechnology, and therapeutics. When combined with the Legobody toolkit, they enable high-resolution cryo-electron ...
The crayfish-rice coculture model contributes to regulating the soil fertility of rice fields and maintaining the stability of soil microbial community composition and function [0.03%]
小龙虾与水稻共养模式有助于调控稻田土壤肥力及维持土壤微生物群落组成和功能的稳定性
Dongdong Wei,Chengguang Xing,Shenzheng Zeng et al.
Dongdong Wei et al.
Rice-fish coculture represents a classic sustainable agricultural paradigm; however, the microecological mechanisms underlying its capacity to maintain soil fertility and microbial community stability remain poorly understood. We conducted ...
EYA4 promotes cellular senescence by enhancing P21 transcription through interaction with SIX2 [0.03%]
EYA4通过与SIX2相互作用增强P21转录来促进细胞衰老
Xiaolin Li,Pingsu Mao,Dandan Chen et al.
Xiaolin Li et al.
During the aging process, the expression levels of numerous genes undergo significant changes, some of which in turn regulate the progression of aging. In this study, we identified the expression of EYA4 is upregulated during aging and demo...
Duckweeds: from fundamental biology to a sustainable plant chassis for biotechnology [0.03%]
水鳖科植物：从基础生物学研究到可持续生物技术平台
Gui-Min Yin,Lin Yang,Sha Li et al.
Gui-Min Yin et al.
Duckweeds (Lemnaceae), the smallest and fastest-growing flowering plants, have emerged as a transformative platform for sustainable biotechnology. This review synthesizes recent advances that underpin their potential as a next-generation pl...