Borna disease virus 2 maintains genomic polymorphisms by superinfection in persistently infected cells [0.03%]
伯纳病毒2通过持久感染的细胞中的超级病毒感染维持基因组多态性
Takehiro Kanda,Pauline Dianne Santos,Dirk Höper et al.
Takehiro Kanda et al.
Mammalian orthobornaviruses, such as Borna disease virus 1 (BoDV-1) and variegated squirrel bornavirus 1, are zoonotic pathogens that cause fatal encephalitis in humans. BoDV-2, another mammalian orthobornavirus with high genetic homology t...
Host genetic diversity contributes to disease outcome in Crimean-Congo hemorrhagic fever virus infection [0.03%]
宿主基因多态性影响克里米亚-刚果出血热病毒感染的后果
Deepashri Rao,Matthew Lewis,Kimberly Meade-White et al.
Deepashri Rao et al.
The Crimean-Congo hemorrhagic fever virus (CCHFV) causes Crimean-Congo hemorrhagic fever (CCHF), a widely distributed disease with significant morbidity and mortality. The virus has high genetic diversity correlated with geographic distribu...
A portrait of the infected cell: how SARS-CoV-2 infection reshapes cellular processes and pathways [0.03%]
感染细胞的画像:SARS-CoV-2如何重塑细胞过程和通路
Valentina Marano,Štěpánka Vlachová,Sofia Maria Luigia Tiano et al.
Valentina Marano et al.
Positive-sense single-stranded RNA (+ssRNA) viruses exert a profound influence on cellular organelles and metabolic pathway by usurping host processes to promote their replication. In this review, we present a portrait of selected cellular ...
Detection of divergent Orthohantavirus tulaense provides insight into wide host range and viral evolutionary patterns [0.03%]
检测出不同类型的Tula汉坦病毒为了解宿主范围广泛性和病毒进化模式提供了见解
Mert Erdin,Teemu Smura,Kursat Kenan Kalkan et al.
Mert Erdin et al.
Orthohantavirus tulaense (TULV) is a member of the orthohantavirus genus and distributed in Europe and Asia. To shed light on TULV epidemiology and evolution, we trapped wild rodents from eastern Turkiye and found 15 TULV positive rodents. ...
Jamaican fruit bat (Artibeus jamaicensis) insusceptibility to mucosal inoculation with SARS-CoV-2 Delta variant is not caused by receptor compatibility [0.03%]
Jamaican果蝠(Artibeus jamaicensis)对Delta变异株黏膜感染不敏感不是由于受体结合能力所致
Julia R Port,Jade C Riopelle,Sarah van Tol et al.
Julia R Port et al.
The ancestral sarbecovirus giving rise to SARS-CoV-2 is posited to have originated in bats. While SARS-CoV-2 causes asymptomatic to severe respiratory disease in humans, little is known about the biology, virus tropism, and immunity of SARS...
Josep Sardanyés,Celia Perales,Esteban Domingo et al.
Josep Sardanyés et al.
Quasispecies theory revolutionized our understanding of viral evolution by describing viruses as dynamic populations of genetically diverse variants constantly adapting. This article explores the theory's role in virus-host interactions, in...
Attenuation of A(H7N9) influenza virus infection in mice exposed to cigarette smoke [0.03%]
接触烟草烟雾小鼠感染A(H7N9)亚型流感病毒的削弱作用研究
Satoshi Fukuyama,Jason E Shoemaker,Dongming Zhao et al.
Satoshi Fukuyama et al.
Influenza A(H7N9) virus showed high pathogenicity in humans when it emerged in 2013. Cigarette smoke (CS) causes pulmonary diseases including bronchitis, emphysema, and lung cancer. Although habitual smoking is thought to increase the risk ...
Novel filoviruses: indication of a global threat or cause to reassess our risk perception? [0.03%]
新的丝状病毒:表明全球威胁还是重新评估我们的风险感知?
Allison Groseth,Thomas Hoenen
Allison Groseth
Filoviruses such as Ebola virus are widely known as causative agents of severe human disease, although apathogenic filoviruses also exist. There is now increasing evidence that filoviruses circulate in almost all parts of the world, where t...
Olga Szewczyk-Roszczenko,Piotr Roszczenko,Yegor Vassetzky et al.
Olga Szewczyk-Roszczenko et al.
Viral diseases continually threaten human health as evolving pathogens introduce new risks. These infections can lead to complications across organ systems, with impacts varying by virus type, infection severity, and individual immune respo...
Cell surface RNA virus nucleocapsid proteins: a viral strategy for immunosuppression? [0.03%]
细胞表面的RNA病毒核衣壳蛋白:一种免疫抑制策略?
Alberto Domingo López-Muñoz,Jonathan W Yewdell
Alberto Domingo López-Muñoz
Nucleocapsid protein (N), or nucleoprotein (NP) coats the genome of most RNA viruses, protecting and shielding RNA from cytosolic RNAases and innate immune sensors, and plays a key role in virion biogenesis and viral RNA transcription. Ofte...