Side-by-side evaluation of two Crimean-Congo hemorrhagic fever virus isolates in IFNAR-/- mice [0.03%]
两个 Crimean-Congo 病毒株在 IFNAR-/- 小鼠中的平行评估研究
Cornelius Rohde,Anke-Dorothee Werner,Michelle Gellhorn Serra et al.
Cornelius Rohde et al.
Crimean-Congo hemorrhagic fever virus (CCHFV) is the causative agent of a severe hemorrhagic fever in humans, associated with case fatality rates up to 40%. Due to the lack of approved vaccines or specific antiviral treatments, CCHFV is cla...
Ecological shifts in avian influenza viruses following HPAIV introductions in southwestern Alaska, 2011-2024 [0.03%]
2011-2024年高致病性禽流感病毒引入后，美国阿拉斯加西南部的低pathogenicity avian influenza virus生态位转换
Christina A Ahlstrom,Laura C Scott,Andrew B Reeves et al.
Christina A Ahlstrom et al.
Southwestern Alaska wetlands are critical staging habitats for migratory waterfowl that breed in western North America and East Asia. Since 2011, samples originating from hunter-harvested waterfowl and environmental feces have been collecte...
Wild carnivores in the Netherlands show molecular and serological evidence of West Nile virus and Usutu virus infection [0.03%]
荷兰野生肉食动物显示西尼罗病毒和乌苏图病毒感染的分子学及血清学证据
Nnomzie C Atama,Cora M Holicki,Emmanuelle Münger et al.
Nnomzie C Atama et al.
Birds are primary reservoirs and amplifying hosts for flaviviruses like West Nile virus (WNV) and Usutu virus (USUV). Wild mammals are also susceptible, although their role remains poorly characterised due to limited studies investigating w...
Application of plant viruses in biotechnology with relation to artificial intelligence, machine learning, and nanotechnology [0.03%]
植物病毒在生物技术、人工智能、机器学习和纳米技术中的应用关系研究
Khushboo Jain,Anchal Saini,Avinash Marwal et al.
Khushboo Jain et al.
Plant viruses, once viewed as harmful agricultural pathogens, are now powerful tools in biotechnology. Their nanoscale structure, self-assembly, and biocompatibility enable applications in agriculture, medicine, and environmental sustainabi...
MPXV H3L elicits broadly directed CD4 T cell responses in mpox patients and MVA vaccinees [0.03%]
MPXV H3L诱导猴痘患者和MVA疫苗接种者产生广谱CD4 T细胞应答
David da Fonseca Araújo,Christoph Schultheiß,Leon Cords et al.
David da Fonseca Araújo et al.
Data on MPXV-specific T-cell responses at the single-peptide level remain limited in patients with mpox and in MVA-BN vaccinees. Here, we characterized the breadth and specificity of MPXV-specific T-cell responses at the single-peptide leve...
A novel adomavirus from proliferative skin lesions of a broadnose sevengill shark (Notorynchus cepedianus) [0.03%]
一种来自广鼻七鳃鰻增生性皮肤损伤的新型腺病毒
Lawrence M Gordon,Joseph L Sevigny,Christopher B Buck et al.
Lawrence M Gordon et al.
In May of 2022, an aquarium-maintained broadnose sevengill shark (Notorynchus cepedianus) developed proliferative skin lesions that prompted pathologic and molecular investigation. Histopathologic examination revealed epidermal hyperplasia ...
Structural and immunogenic characterisation of ChAdOx1 Chik-derived Chikungunya VLPs supports a mechanistic rationale for vaccine-induced protection [0.03%]
结构和免疫学特征表征了ChAdOx1 Chik衍生的 chickungunya VLPs，支持了疫苗保护作用的机制原理
Young Chan Kim,Xiyong Song,Yasunori Watanabe et al.
Young Chan Kim et al.
Chikungunya virus (CHIKV) is a mosquito-borne alphavirus that causes severe chronic arthritis in humans and constitutes an expanding global threat. We previously reported that a single unadjuvanted dose of ChAdOx1 Chik vaccine was safe and ...
Single molecule super resolution microscopy reveals formation of Dengue NS2B3 cluster on mitochondrial network and its effect on fragmentation [0.03%]
单分子超分辨率显微镜揭示登革病毒NS2B3聚集体在细胞线粒体网络上及其对线粒体分裂的影响
Jiby M Varghese,Prakash Joshi,Aravinth S et al.
Jiby M Varghese et al.
It is challenging to understand viral proteins at a single-molecule level and visualize their dynamics in a cellular environment. This calls for sophisticated microscopy techniques (such as,SMLM) and single-molecule analysis that can reveal...
A bovine H5N1 virus efficiently replicates in differentiated human nasal epithelial cells [0.03%]
一种牛源H5N1病毒可在分化的人鼻上皮细胞中高效复制
Étori Aguiar Moreira,Samuel Constant,Charlène Constant et al.
Étori Aguiar Moreira et al.
Highly pathogenic avian influenza (H5N1) viruses of clade 2.3.4.4b have caused significant losses in bird populations worldwide and repeatedly infected mammals, including humans, without sustained human to human transmission. Here we show t...
Development of an immunochromatographic lateral flow assay for the rapid detection of all known orthoebolavirus glycoproteins [0.03%]
一种用于快速检测所有已知正埃博拉病毒糖蛋白的免疫层析侧流法的发展
Helene Schulz,Guodong Liu,Jordan Wight et al.
Helene Schulz et al.
Orthoebolaviruses, like Ebola, Sudan, and Bundibugyo viruses, are responsible for causing sporadic and unpredictable outbreaks of severe disease throughout Sub-Saharan Africa. Accurate and reliable diagnostic tests are key to identifying ca...