Mikail D Levasseur
Mikail D Levasseur
Zoonotic viruses rank among the greatest threats to public health, with urbanization and global warming accelerating their emergence and spread. As the risk of future pandemics grows, innovative tools are needed to deepen our understanding ...
Enhanced neurotropism of bovine H5N1 compared to the Vietnam H5N1 isolate in C57BL/6J mice [0.03%]
与中国H5N1毒株相比，牛源H5N1病毒具有更显著的神经嗜性
Kerry Goldin,Sarah van Tol,Randall C Johnson et al.
Kerry Goldin et al.
In this study, we investigated differences in tissue tropism of two HPAI H5N1 strains, the isolate A/Vietnam/1203/2004 (VN1203) isolated from a fatal human case in 2004 and the bovine isolate A/Bovine/Ohio/B24osu-342/2024 (Bov342) isolated ...
Development of Langat virus infectious clones as a platform for live-attenuated tick-borne encephalitis vaccine [0.03%]
莱加特病毒感染性克隆作为活减毒蜱传脑炎疫苗平台的发展研究
Naveed Asghar,Rita Jaafar,Anna Valko et al.
Naveed Asghar et al.
Tick-borne encephalitis (TBE) is one of the most important tick-transmitted diseases in Europe and Asia. With no specific antiviral treatment available, vaccination remains the most effective protective strategy for TBE. Unlike currently av...
Author Correction: Transmission dynamics of avian influenza viruses in Egyptian poultry markets [0.03%]
作者更正：埃及家禽市场中禽流感病毒的传播动力学
Sara H Mahmoud,Mokhtar Gomaa,Ahmed El Taweel et al.
Sara H Mahmoud et al.
Published Erratum
Npj viruses. 2025 May 22;3(1):41. DOI:10.1038/s44298-025-00130-z 2025
Characterization of A(H1N1)pdm09 influenza viruses isolated between 2016 and 2019 [0.03%]
2016-2019年分离的A(H1N1)pdm09流感病毒的特征分析
Luthfi Muawan,Kosuke Takada,Sara Yoshimoto et al.
Luthfi Muawan et al.
The A(H1N1)pdm09 virus, which caused the 2009 influenza pandemic, has continued to circulate in humans for over a decade. Understanding its biological properties is crucial for effective surveillance, prevention, and control. Here, we chara...
Kinetic MUNANA assay reveals functionally relevant antibody epitopes on Influenza A virus neuraminidase [0.03%]
Kinetic MUNANA测定揭示了流感病毒神经氨酸酶上具有功能相关性的抗体表位
Ilya V Smirnov,Danica F Besavilla,Karin Schön et al.
Ilya V Smirnov et al.
Influenza A virus neuraminidase (NA) is drawing attention as a target for vaccine development. In this study, we propose kinetic MUNANA assay as a tool to identify monoclonal antibodies (mAbs) that specifically target functional epitopes on...
SARS-CoV-2 variants retain high airborne transmissibility by different strategies [0.03%]
新冠病毒变异株通过不同策略保持高水平的空气传播性
Jie Zhou,Ksenia Sukhova,Rebecca Frise et al.
Jie Zhou et al.
SARS-CoV-2 variants evolve to balance immune evasion and airborne transmission, yet the mechanisms remain unclear. In hamsters, first-wave, Alpha, and Delta variants transmitted efficiently via aerosols. Alpha emitted fewer viral particles ...
Cytochrome b5 occurrence in giant and other viruses belonging to the phylum Nucleocytoviricota [0.03%]
属于Nucleocytoviricota门的巨型病毒和其他病毒中细胞色素b5的存在
David C Lamb,Jared V Goldstone,Djamal Brahim Belhaouari et al.
David C Lamb et al.
Cytochrome b5 is an electron transport protein found in eukaryotes and bacteria, and plays roles in energy production, lipid biosynthesis and cytochrome P450 biochemistry. Here we report that genes for cytochrome b5 occur broadly among viru...
Potent bivalent nanobody constructs that protect against the SARS-CoV-2 XBB variant [0.03%]
能有效抵御SARS-CoV-2 XBB变异株的双价纳米抗体构建体
Peter J Halfmann,Jeong Soo Lee,Nikki McArthur et al.
Peter J Halfmann et al.
Most antibody-based therapeutics approved for SARS-CoV-2 treatment have shown greatly reduced neutralization activity against emerging Omicron variants. To target recent Omicron variants, we developed XBB-specific antibody-like therapeutics...