Mpox in Central Africa: complex epidemiology requires a constellation approach [0.03%]
中非猴痘：复杂流行病学需要综合方法
Megan Halbrook,Jean Claude Makangara-Cigolo,Sydney Merritt et al.
Megan Halbrook et al.
Currently Central Africa is experiencing multiple large concurrent mpox outbreaks spreading across several nations and at-risk populations via multiple transmission modes. This current surge of cases, framed in the context of the 2022 globa...
Genetic diversity of Toscana virus glycoproteins affects the kinetics of virus entry and the infectivity of newly produced virions [0.03%]
托斯卡纳病毒糖蛋白的遗传多样性影响病毒进入的动力学和新产生病毒体的感染性
Adrien Thiesson,Marie-Pierre Confort,Sophie Desloire et al.
Adrien Thiesson et al.
Toscana virus (TOSV) is a pathogenic and transmissible Phlebovirus of the Bunyavirales order. To date, two principal genetic lineages (A and B) have been identified and the impact of TOSV genetic diversity on its biology is still unknown. W...
E M Abdelwhab,Martin Beer
E M Abdelwhab
The H5 subtype of highly pathogenic avian influenza viruses represents a significant challenge to animal and human health. H5 clade 2.3.4.4b viruses have experienced an unprecedented global spread, coupled with remarkable genetic plasticity...
Inferring enterovirus D68 transmission dynamics from the genomic data of two 2022 North American outbreaks [0.03%]
基于基因组数据推断两起2022年北美EV-D68爆发的传播动力学
Martin Grunnill,Alireza Eshaghi,Lambodhar Damodaran et al.
Martin Grunnill et al.
Enterovirus D68 (EV-D68) has emerged as a significant cause of acute respiratory illness in children globally, notably following its extensive outbreak in North America in 2014. A recent outbreak of EV-D68 was observed in Ontario, Canada, f...
Genome sequencing identifies "Limestone Canyon virus" as Montaño virus (Hantaviridae: Orthohantavirus montanoense) circulating in brush deermice in New Mexico [0.03%]
基因组测序将"Limestone Canyon病毒"鉴定为在新墨西哥州灌木鹿鼠中循环的蒙塔诺病毒(Hantaviridae:Orthohantavirus montanoense)
Samuel M Goodfellow,Robert A Nofchissey,Valerie J Morley et al.
Samuel M Goodfellow et al.
Orthohantaviruses infect distinct eulipotyphlan and rodent reservoirs throughout the world; some rodent orthohantaviruses can cause disease in humans. In the United States, a primary rodent reservoir for the human-pathogenic Sin Nombre viru...
Diagnosis and genomic characterization of the largest western equine encephalitis virus outbreak in Uruguay during 2023-2024 [0.03%]
乌拉圭西部马脑炎病毒2023-2024年最大规模暴发的诊断和基因组特征分析
Gonzalo Tomás,Ana Marandino,Sirley Rodríguez et al.
Gonzalo Tomás et al.
The Western equine encephalitis virus is transmitted between mosquitoes and wild birds. Mosquitoes spread the virus to horses and human populations, causing severe encephalitis and death. The most recent large outbreak occurred in South Ame...
Strange relatives: the enigmatic arbo-jingmenviruses and orthoflaviviruses [0.03%]
奇特的远亲：谜一般的arbjo-virus和orthoflavi病毒
Edwin O Ogola,Amitava Roy,Kurt Wollenberg et al.
Edwin O Ogola et al.
Arthropod - and vertebrate-associated jingmenviruses (arbo-JMV) have segmented positive-strand RNA genomes and are provisional members of the genus Orthoflavivirus (family Flaviviridae). Current investigations have described arbo-JMV infect...
Human macrophages infected with Egyptian Rousette bat-isolated Marburg virus display inter-individual susceptibility and antiviral responsiveness [0.03%]
埃及方头蝠分离的马堡病毒感染的人巨噬细胞系之间易感性和抗病毒反应性存在个体差异
Ivet A Yordanova,Angelika Lander,Annette Wahlbrink et al.
Ivet A Yordanova et al.
Marburg virus (MARV) is a highly pathogenic filovirus and a causative agent of sporadic zoonotic viral hemorrhagic fever outbreaks with high case fatality rates. In humans, filoviruses like MARV and Zaire Ebola virus (EBOV) target, among ot...
Organoids in virology [0.03%]
病毒学中的类器官研究
Julie T S Chu,Mart M Lamers
Julie T S Chu
To adequately prepare against imminent disease outbreaks from diverse and ever-changing viral pathogens, improved experimental models that can accurately recapitulate host-virus responses and disease pathogenesis in human are essential. Org...
Automated and virus variant-programmable surrogate test qualitatively compares to the gold standard SARS-CoV-2 neutralization assay [0.03%]
一种自动化且可编程的替代检测方法能与新冠病毒中和试验黄金标准相媲美
Danielle W Ali,Maggie L Bartlett,Christopher D Heger et al.
Danielle W Ali et al.
The ongoing emergence of new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants underscores the need for rapid, adaptable, high-throughput testing. However, assays for neutralizing antibodies, which are a good measure of ...