Metabolic interference impairs influenza A virus replication by dampening vRNA synthesis [0.03%]
代谢干扰通过抑制病毒RNA合成来阻碍甲型流感病毒感染复制
Jens Kleinehr,Chiara Robin Bojarzyn,Michael Schöfbänker et al.
Jens Kleinehr et al.
For replication, viruses exploit the host cell metabolism for biosynthesis of viral components. Recently, we could show that inhibition of glycolysis interfered with IAV replication by impairing the regulation of the viral polymerase as a t...
Tracing household transmission of SARS-CoV-2 in New Zealand using genomics [0.03%]
运用基因组学追踪新西兰家庭中的SARS-CoV-2传播路线
Lauren Jelley,Nayyereh Aminisani,Meaghan O&#x;Neill et al.
Lauren Jelley et al.
By early 2022, the highly transmissible Omicron variant of SARS-CoV-2 had spread across most of the world. For the first time since the pandemic began, New Zealand was experiencing high levels of community transmission of SARS-CoV-2. We enr...
Airborne transmission efficiency of SARS-CoV-2 in Syrian hamsters is not influenced by environmental conditions [0.03%]
环境条件不会影响叙利亚仓鼠中SARS-CoV-2的气溶胶传播效率
Claude Kwe Yinda,Julia R Port,Trenton Bushmaker et al.
Claude Kwe Yinda et al.
Several human respiratory viruses display a clear seasonal pattern with a higher incidence in the winter season in temperate regions. We previously determined that SARS-CoV-2 is more stable at low-temperature and low-humidity conditions com...
Multivalent interactions between fully glycosylated influenza virus hemagglutinins mediated by glycans at distinct N-glycosylation sites [0.03%]
不同N-连接糖基化位点介导的完全糖基化的流感病毒血凝素之间的多价相互作用
Ruofan Li,Jingjing Gao,Lin Wang et al.
Ruofan Li et al.
The hemagglutinin (HA) glycoprotein of influenza virus binds host cell receptors and mediates viral entry. Here we present cryo-EM structures of fully glycosylated HAs from H5N1 and H5N8 influenza viruses. We find that the H5N1 HA can form ...
Renewed insights into Ackermannviridae phage biology and applications [0.03%]
_ackermann噬菌体生物学和应用的新见解_
Anders Nørgaard Sørensen,Lone Brøndsted
Anders Nørgaard Sørensen
The Ackermannviridae family was established in 2017, containing phages previously classified within the Myoviridae family under the Viunalikevirus genus. Ackermannviridae phages have been increasingly studied due to their broad range of hos...
Influenza B viruses are more susceptible to high temperatures than influenza A viruses [0.03%]
甲型流感病毒和乙型流感病毒对高温敏感性不同
Kosuke Takada,Yurie Kida,Shinji Watanabe et al.
Kosuke Takada et al.
Seasonal influenza is caused by two subtypes of influenza A virus (A/H1N1 and A/H3N2) and two lineages of influenza B viruses (B/Victoria-lineage and B/Yamagata-lineage). Seasonal influenza viruses replicate efficiently in the human upper r...
Reshma Koolaparambil Mukesh,Claude K Yinda,Vincent J Munster et al.
Reshma Koolaparambil Mukesh et al.
Coronaviruses (CoVs) have caused three global outbreaks: severe acute respiratory syndrome coronavirus 1 (SARS-CoV-1) in 2003, Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012, and SARS-CoV-2 in 2019, with significant mortali...
Author Correction: Mpox in Central Africa: complex epidemiology requires a constellation approach [0.03%]
作者更正：中非猴痘：复杂流行病学需要多管齐下的方法
Megan Halbrook,Jean Claude Makangara-Cigolo,Sydney Merritt et al.
Megan Halbrook et al.
Published Erratum
Npj viruses. 2025 Feb 21;3(1):11. DOI:10.1038/s44298-025-00097-x 2025
Vertical and horizontal transmission of plant viruses: two extremes of a continuum? [0.03%]
植物病毒的水平和垂直传播：连续体的两极？
Lucía García-Ordóñez,Israel Pagán
Lucía García-Ordóñez
Parasites have a variety of mechanisms to be transmitted to new susceptible hosts, which can be largely grouped in two main modes: vertical (i.e., from parents to the offspring) and horizontal (i.e., between hosts regardless of descent). Be...
Transmission dynamics of avian influenza viruses in Egyptian poultry markets [0.03%]
埃及家禽市场中的禽流感病毒传播动力学研究
Sara H Mahmoud,Mokhtar Gomaa,Ahmed El Taweel et al.
Sara H Mahmoud et al.
Live bird markets (LBMs) are considered hotspots for Avian Influenza Viruses (AIVs). In such markets, AIVs pose threats to both poultry and public health. Within LBMs, AIVs spread through various routes, including direct contact, environmen...