Lentogenic avian paramyxovirus 1 of both class I and class II are circulating in danish wild and commercial waterfowl [0.03%]
丹麦野生和商业雁鸭中一类和二类迟发型禽副黏病毒1在 circulation
Karen Martiny,Yuan Liang,Pia Ryt-Hansen et al.
Karen Martiny et al.
Newcastle disease, a notifiable avian disease, is caused by virulent avian paramyxovirus 1 (APMV-1). In this study, we screened samples collected through the active and passive surveillance for avian influenza virus in Denmark between 2014 ...
Reduced cross-protective potential of Omicron compared to ancestral SARS-CoV-2 spike vaccines against potentially zoonotic coronaviruses [0.03%]
与祖先SARS-CoV-2刺突疫苗相比，奥密克戎针对潜在动物源性冠状病毒的交叉保护力减弱
Tyler M Renner,Matthew Stuible,Brian Cass et al.
Tyler M Renner et al.
The COVID-19 pandemic has emphasised the importance of vaccines and preparedness against viral threats crossing species barriers. In response, a worldwide vaccination campaign targeting SARS-CoV-2 was implemented, which provides some cross-...
Backsplicing of the HIV-1 transcript generates multiple circRNAs to promote viral replication [0.03%]
HIV-1转录本的反向剪接产生多种环状RNA以促进病毒复制
Christopher Mauer,Sean Paz,Massimo Caputi
Christopher Mauer
Circular RNAs (circRNAs) are a family of non-coding RNAs that originate from a non-canonical splicing event (backsplicing) that forms covalently closed continuous loops. An analysis of the human immunodeficiency type 1 virus (HIV-1) complex...
Monica Mirolo,Bianca Kühl,Melvin Daniel Roji et al.
Monica Mirolo et al.
The discovery of several novel hepatovirus species in marine and terrestrial mammals has expanded the recognised members of the genus Hepatovirus and has provided better understanding on the evolutionary origins of human hepatovirus A (HAV)...
Author Correction: Dominant HPAIV H5N1 genotypes of Germany 2021/2022 are linked to high virulence in Pekin ducklings [0.03%]
作者更正：德国2021/2022年主要的高致病性禽流感H5N1基因型与北京鸭雏高的毒力有关
Ronja Piesche,Angele Breithaupt,Anne Pohlmann et al.
Ronja Piesche et al.
Published Erratum
Npj viruses. 2024 Nov 18;2(1):56. DOI:10.1038/s44298-024-00071-z 2024
Transmission dynamics of MERS-CoV in a transgenic human DPP4 mouse model [0.03%]
人DPP4转基因小鼠模型中的MERS-CoV传播动力学研究
Neeltje van Doremalen,Trenton Bushmaker,Robert J Fischer et al.
Neeltje van Doremalen et al.
Since 2002, three novel coronavirus outbreaks have occurred: severe acute respiratory syndrome coronavirus (SARS-CoV-1), Middle East respiratory syndrome coronavirus (MERS-CoV), and SARS-CoV-2. A better understanding of the transmission pot...
Resistance to SARS-CoV-2 infection in camelid nasal organoids is associated with lack of ACE2 expression [0.03%]
骆驼科动物鼻器官样组织对SARS-CoV-2感染的抵抗与缺乏ACE2表达有关
Tim I Breugem,Samra Riesebosch,Debby Schipper et al.
Tim I Breugem et al.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects a variety of animal species. Susceptibility to SARS-CoV-2 is primarily determined by the utilization of the viral receptor, ACE2. SARS-CoV-2 can utilize a broad range ...
In vitro and in vivo characterization of a novel West Nile virus lineage 2 strain [0.03%]
一种新型西尼罗病毒2系毒株的体外和体内特征分析
Imke Visser,Eleanor M Marshall,Gianfilippo Agliani et al.
Imke Visser et al.
Over recent decades, West Nile virus (WNV) has continued to expand its geographical range, emerging in previously non-endemic areas, including northern Europe. In Europe, WNV lineage 2 strains are most prevalent and cause sporadic outbreaks...
The endoplasmic reticulum (ER): a crucial cellular hub in flavivirus infection and potential target site for antiviral interventions [0.03%]
内质网（ER）： flavivirus感染中的重要细胞中心及潜在的抗病毒作用位点
Marijke Verhaegen,Kurt Vermeire
Marijke Verhaegen
Dengue virus (DENV) is the most prevalent arthropod-borne flavivirus and imposes a significant healthcare threat worldwide. At present no FDA-approved specific antiviral treatment is available, and the safety of a vaccine against DENV is st...
Nucleotide sequence as key determinant driving insertions at influenza A virus hemagglutinin cleavage sites [0.03%]
禽流感病毒血凝素裂解位点插入的关键核苷酸序列决定因素
Monique I Spronken,Mathis Funk,Alexander P Gultyaev et al.
Monique I Spronken et al.
Highly pathogenic avian influenza viruses (HPAIVs) emerge from H5 and H7 low pathogenic avian influenza viruses (LPAIVs), most frequently upon insertions of nucleotides coding for basic amino acids at the cleavage site (CS) of the hemagglut...