Hybrid bioprinting of hierarchical vascular networks at capillary-scale resolution [0.03%]
具有毛细管分辨率的分层血管网络的混合生物打印技术
Yuxuan Liao,Salvador Gallegos-Martínez,Xiao Kuang et al.
Yuxuan Liao et al.
Replicating the intricate hierarchical architecture of natural vascular networks, especially at capillary-scale resolution, remains a pivotal challenge in organ fabrication. Here we present a machine learning-enhanced hybrid bioprinting str...
Hydrogen evolution and dynamics in hydrogel electrochemical cells for ischemia-reperfusion therapy [0.03%]
用于缺血再灌注治疗的水凝胶电解池中的氢气析出及动力学研究
Wen Li,Jing Zhang,Romain Nith et al.
Wen Li et al.
Molecular hydrogen (H2) protects organs from reactive oxygen species damage associated with ischemia-reperfusion (I/R) injury. Existing H2 delivery methods, such as gas inhalation and H2-rich water consumption, target the entire body and ex...
Photoreforming of solid waste on 1 m2 scale using single-source precursor-derived co-catalyst films [0.03%]
基于单源前驱体共催化剂膜的固废光电 reforming 中试研究
Ariffin Bin Mohamad Annuar,Yongpeng Liu,Subhajit Bhattacharjee et al.
Ariffin Bin Mohamad Annuar et al.
Photocatalytic reforming offers a route to valorize biomass and plastic waste into clean H2 under ambient conditions. However, the scalability of photocatalyst sheets is limited by high-temperature processing, binders and complex co-catalys...
Shuyuan Zhang,Jiyizhe Zhang,Alexei A Lapkin
Shuyuan Zhang
A digital twin, which virtually replicates a real system and fuses data, models and domain knowledge, is a key technology for accelerating chemical process development and addressing sustainability challenges. Despite its potential, one cri...
Neural network-assisted personalized handwriting analysis for Parkinson's disease diagnostics [0.03%]
基于神经网络的帕金森病辅助个性化手写分析诊断方法研究
Guorui Chen,Trinny Tat,Yihao Zhou et al.
Guorui Chen et al.
Diagnosing Parkinson's disease (PD) promptly, accessibly and effectively is crucial for improving patient outcomes, yet reaching this goal remains a challenge. Here we developed a diagnostic pen featuring a soft magnetoelastic tip and ferro...
Transient pH changes drive vacuole formation in enzyme-polymer condensates [0.03%]
瞬时pH变化驱动酶聚合物凝聚体内液泡的形成
Nisha Modi,Raghavendra Nimiwal,Jane Liao et al.
Nisha Modi et al.
Membraneless organelles are essential for cellular function. These biomolecular condensates often exhibit complex morphologies in response to biological stimuli. In vitro condensate models help elucidate how these multiphase assemblies form...
Water dissociation efficiencies control the viability of reverse-bias bipolar membranes for CO2 electrolysis [0.03%]
水分解效率控制CO2电解的反向偏置双极膜的活性
Gerard Prats Vergel,Huan Mu,Nikita Kolobov et al.
Gerard Prats Vergel et al.
Bipolar membranes operated under reverse-bias (r-BPM) provide the only potential route to use anodes free of platinum group metals in CO2 electrolyzers when paired with the oxygen evolution reaction. Under 100% water dissociation efficiency...
Growing functional artificial cytoskeletons in the viscoelastic confinement of DNA synthetic cells [0.03%]
DNA合成细胞粘弹性限制中的功能人工细胞骨架生长
Weixiang Chen,Siyu Song,Avik Samanta et al.
Weixiang Chen et al.
Intracellular structures, such as cytoskeletons, form within a crowded cytoplasm with viscoelastic properties. While self-assembly in crowding is well studied, the effects of coupled viscoelastic environments remain elusive. Here we enginee...
Probing dynamic oxygen exchange for hydrogen production with operando neutron diffraction [0.03%]
运用原位中子衍射探测产氢过程中的动态氧交换作用
Daniel M Telford,Alex Martínez Martín,Matthew D Guy et al.
Daniel M Telford et al.
A chemical looping process exploiting the variable oxygen content of ABO3-δ perovskite materials can achieve super-equilibrium conversions of societally important reactions such as the water-gas shift reaction (CO + H2O ⇋ CO2 + H2). The a...
Engineering Considerations for Developing Next-Generation Oligonucleotide Therapeutics [0.03%]
下一代寡核苷酸药物开发中的工程学考量因素
Sasha B Ebrahimi,Himanshu Bhattacharjee,Sujatha Sonti et al.
Sasha B Ebrahimi et al.
Oligonucleotide therapeutics are revolutionizing disease treatment by regulating molecules at the genetic level, offering the possibility of treating conditions that were once considered "undruggable." However, delivering oligonucleotides t...