Supervised-Learning-Driven Interrogation of Organ-on-a-Chip Quality from Microscopy Images [0.03%]
基于监督学习的器官芯片显微图像质量评估方法研究
Rose Mary George,Kenry
Rose Mary George
We leverage supervised learning to realize high-throughput and objective interrogation of organ-on-a-chip quality from microscopy images. More than 600 images of two lung-related cell types in good and bad quality lung-on-a-chip models are ...
Multimodal Modeling for Polymer Property Prediction and Decoupling of Structure-Property Relationship [0.03%]
用于聚合物性能预测的多模态建模及其构效关系解耦
Renquan Lv,Weiwei Han,Zixu Zeng et al.
Renquan Lv et al.
The key challenge in the development of a target property polymer stems from the unclear structure-property relationship (SPR). A multimodal graph neural network (GNN) framework, GeoALBEF, is proposed to address this problem. GeoALBEF intro...
Molecularly Imprinted Membranes for Selective Biomarker Recognition: Recent Advances and Emerging Strategies [0.03%]
分子印迹膜在生物标志物识别中的应用：最近进展与新兴策略
Qingmei Song,Kelly Van Van,Xinhao Li et al.
Qingmei Song et al.
Molecularly imprinted membranes (MIMs) epitomize the convergence of membrane science with molecular imprinted technology. Endowed with intrinsic molecular recognition and memory functionalities, MIMs have the potential to evolve into pivota...
Photo-Cross-Linkable Polysaccharide-Based Multilayered Films for Durable Micropatterned Antifogging Surfaces [0.03%]
用于耐久微图案除雾表面的光交联多层 polysaccharide 薄膜
Hyein Jin,Min Ryu,Hyomin Lee
Hyein Jin
Antifogging coatings with high durability and spatial controllability are essential for advanced optical applications operating under humid or thermally dynamic environments. Herein, we report the design and fabrication of robust, photo-cro...
Recent Advances in Machine Learning Models for Predicting Toxicity of Inorganic Nanoparticles [0.03%]
用于预测无机纳米粒子毒性的机器学习模型的新进展
Mingli Li,Qiao-Zhi Li,Yuliang Zhao et al.
Mingli Li et al.
Nanoparticles (NPs) such as engineered inorganic NPs (metals, metal oxides, carbon materials, etc.) can induce cytotoxicity in normal biological systems when used for disease treatment or when exposed to the environment, which has raised wi...
Scalable Room-Temperature Synthesis of the Ultramicroporous Metal-Organic Framework for Separation of the C2H6/ C2H4 Mixture [0.03%]
一种可在室温下合成超微孔金属有机骨架材料以分离乙烷/乙烯混合物的新方法
Yu Zhang,Ting Wang,Xia Li et al.
Yu Zhang et al.
Ethylene (C2H4) is a vital industrial chemical with a growing market, similarly produced through the steam cracking of hydrocarbons, such as ethane (C2H6). However, separating C2H4 from a C2H6 and C2H4 mixture remains challenging due to the...
Jianbiao Wang,Deviprasath Chinnadurai,Zhi Wei Seh
Jianbiao Wang
Automated Genetic Manipulation for the Construction of Pichia pastoris Cell Factories [0.03%]
甲基球拟酵母细胞工厂的自动化遗传操作构建技术
Yimeng Zuo,Lingling Jin,Jiachen Zhang et al.
Yimeng Zuo et al.
As a nonmodel microorganism, Pichia pastoris has unique advantages in recombinant protein expression and natural product biosynthesis. The development of synthetic biology has provided key technical support for the construction of microbial...
Semirational Protein Engineering Yields Archaerhodopsin-3-Based Fluorescent Genetically Encoded Voltage Indicators with Enhanced Brightness and Red Shifted Absorption Bands [0.03%]
半理性蛋白质工程得到的Archaeorhodopsin-3基荧光遗传编码电压指示器具有更高的亮度和红移吸收带
Dmitrii M Nikolaev,Ekaterina M Metelkina,Nikita A Domskii et al.
Dmitrii M Nikolaev et al.
A semirational engineering of novel bright variants of archaerhodopsin-based genetically encoded voltage indicators (GEVIs) is performed. The corresponding focused protein sequence library was generated using data derived from prior directe...
Recent Advancements in Bionic Olfactory Biosensors: Components, Applications, and Future Perspectives [0.03%]
仿生嗅觉生物传感器的近期进展：组件、应用及未来展望
Jingyi Li,Yi Feng,Jun Ge
Jingyi Li
Organisms in nature are skilled engineers, equipped with highly evolved sensory systems that enable the precise perception and discrimination of a wide array of environmental stimuli. Among these, the olfactory system exhibits a strong capa...