Modular Biosurface Engineering of Magnetotactic Bacteria for Multimodal Synergistic Cancer Therapy [0.03%]
用于多模态协同癌症治疗的磁趋细菌模块化生物表面工程
Qilong Li,Wangqing Li,Xuefei Sun et al.
Qilong Li et al.
Bacterial-mediated cancer therapy shows therapeutic potential yet remains constrained by bioavailability and biosafety challenges. We introduce a scalable, modular biosurface-engineering platform for functionalizing wild-type magnetotactic ...
Enhancing Diastereoselectivity of l‑Threonine Aldolase by Strengthening Kinetic Control To Mitigate Thermodynamic Equilibrium [0.03%]
通过增强动力学控制来加强L-苏阿糖酸盐aldol酶的非对映选择性以缓解热力学平衡问题
Wenlong Zheng,Sai Fang,Chennuo Zhu et al.
Wenlong Zheng et al.
The reaction catalyzed by l-threonine aldolase (LTA) for the formation of β-hydroxy-α-amino acids is governed by both kinetic and thermodynamic control, causing the diastereoselectivity of LTA to gradually decrease as the reaction progres...
Ye Wang,Yinuo Xie,Rong Dong et al.
Ye Wang et al.
Bioelectrocatalytic conversion of organic waste uses renewable electricity to convert organic waste into high-value chemicals and fuels under mild conditions. It is regarded as a strategic link connecting waste refinement and the green econ...
Microfiltration of Selective Polysaccharides Using Inexpensive Fuller's Earth-Based Ceramic Membranes [0.03%]
一种使用廉价材料制备的陶瓷膜选择性提取多糖的微滤方法
Maddala Sree Kanth,Gourhari Chakraborty,Vijaykumar Sudarshana Deepa et al.
Maddala Sree Kanth et al.
This study presents a microfiltration approach for separating polysaccharides using an unprecedented ceramic membrane made from affordable Fuller's earth. The membrane was created through uniaxial hydraulic pressing and sintered at 850 °C,...
Mg2+-Dependent Remodeling of Biomolecular Condensates' Microenvironments for Tunable Molecular Uptake and Altered Biochemical Dynamics [0.03%]
利用 Mg2+ 重编程生物分子凝聚体的微环境以实现可调物质摄取和改变生化动力学性能
Yifeng Zhu,Xinran Yu,Chengying Yin et al.
Yifeng Zhu et al.
Biomolecular condensates have emerged as a transformative paradigm in biomedical and materials sciences due to their unique capacity for molecular sequestration and dynamic adaptability. Precise modulation of their microenvironmental proper...
Ultrasound-Activated Prodrugs for Precision Cancer Therapy: From Mechanical and Cavitation Effects to Advanced Sonochemical Activation [0.03%]
用于精确癌症治疗的超声激活前药：从机械和空化效应到先进的声化学活化
Xitong Ren,Hui Zhang,Jingxuan Zhang et al.
Xitong Ren et al.
Small-molecule drugs remain the mainstay of cancer therapy but are frequently compromised by poor tumor selectivity and dose-limiting systemic toxicity. Prodrug strategies have therefore been widely developed to improve therapeutic indices;...
Mathematical Modeling of Biomass Pyrolysis in Fixed-Bed Reactors: A Systematic Review of Trends, Challenges, and Perspectives [0.03%]
固定床反应器中生物质热解的数学建模：趋势、挑战及展望系统性 review
Vilmar Steffen,Maiquiel Schmidt de Oliveira,Edson Antonio da Silva
Vilmar Steffen
Accurate simulation of biomass pyrolysis in fixed-bed reactors is crucial for optimizing this promising thermochemical conversion pathway. This review systematically consolidates and critically evaluates contemporary mathematical models tha...
Yuting Xiao,Xiaojing Li,Mingsong Zhou et al.
Yuting Xiao et al.
Lignin-based microcapsules exhibit promising potential among natural sunscreen agents. However, their applications are hindered by poor photostability and biocompatibility of core materials. Here, we optimize the core formulation of lignin ...
3D Aerohydrogel Scaffolds for Brain Tissue Engineering and In Vitro Neuroscience [0.03%]
用于脑组织工程和体外神经科学的3D气凝胶支架
Torge Hartig,Luise Schlotterose,Grace Atteh et al.
Torge Hartig et al.
The development of 3D scaffolds addresses a critical gap in neural tissue modeling by mimicking the physiological architecture in brain cell culture. This is a key challenge to improve the reliability of in vitro assays and reduce animal te...
Direct Regeneration of Spent LiNi0.8Co0.1Mn0.1O2 into Ce-Doped Single-Crystal Cathodes [0.03%]
用于直接再生废LiNi0.8Co0.1Mn0.1O2正极的Ce掺杂单晶电极技术
Yudi Shao,Shuaipeng Hao,Fangyan Liu et al.
Yudi Shao et al.
The widespread deployment of lithium-ion batteries (LIBs) is driving a steep rise in end-of-life batteries, heightening resource and environmental burdens and underscoring the need for efficient recycling. Direct regeneration, with its simp...