Urinary Organophosphate Esters and Increased Oxidative Stress in Healthy Older Adults: The China BAPE Study [0.03%]
中国BAPE研究中健康老年人尿液有机磷酯与氧化应激增强的关系
Chenfeng Li,Xiaojie Guo,Huimin Ren et al.
Chenfeng Li et al.
Exposure to organophosphate esters (OPEs) is associated with the development of geriatric diseases. However, the impact of OPEs on oxidative stress, a precursor of geriatric diseases, remains unclear in older adults. Based on the China BAPE...
Exploring the Impact of E‑Waste Exposure on Childhood Blood Pressure: Metabolomics Analysis and Risk Prediction [0.03%]
电子废物暴露对儿童血压影响的代谢组学分析及风险预测模型研究
Meng-Yang Li,Tian-Hong Chen,Ye Liu et al.
Meng-Yang Li et al.
The alarming burden of hypertension in electronic waste (e-waste) recycling areas (EA) constitutes a pressing public health challenge. While growing evidence links changes in blood pressure to volatile organic compounds (VOCs) and metal-(lo...
Population-Level Amplicon and Metagenomic Analyses Uncover Distinct Effects of Landscape-Level Pesticides on the Maternal Gut Microbiome [0.03%]
基于人群的扩增子和宏基因组分析揭示了景观水平农药对母体肠道微生物群的不同影响
Hongcheng Wei,Yifan Xu,Bowen Jin et al.
Hongcheng Wei et al.
The environment dominates over host genetics in shaping the gut microbiome, which plays a pivotal role in modulating human health. Experimental evidence supports the notion that exposure to pesticides could perturb the gut microbiome, and t...
Residents Face Severe Environmental Health Risks amid the Spiritual Happiness during the Spring Festival: An Evidence from Rural Northern China [0.03%]
春节期间精神愉悦下的身体风险：来自中国北方农村的证据
Zhi Gao,Zizhen Zhao,Hanning Wang et al.
Zhi Gao et al.
The Spring Festival, a cornerstone of Chinese cultural heritage, fosters family reunions. However, its traditional practices, such as burning incense and setting off fireworks, generate severe air pollution and pose significant health threa...
Characterizing Prenatal Exposure to Contemporary and Emerging Chemicals in a Prospective Cohort of Pregnant Women in Atlanta, Georgia [0.03%]
表征佐治亚州亚特兰大前瞻性孕妇队列中当代和新兴化学物质的围产期暴露状况
Kaegan Ortlund,Anne L Dunlop,Dana Boyd Barr et al.
Kaegan Ortlund et al.
Epidemiological evidence links chemical exposure during pregnancy to adverse maternal and child health outcomes, yet only a fraction of chemicals used in commerce in the United States (US) are biomonitored nationally and have undergone comp...
Seasonality in Mortality and Health: Environmental and Demographic Perspectives [0.03%]
mortality and health的季节性变化：环境与人口视角
Lina Madaniyazi,Aurelio Tobias,Sergi Trias-Llimós et al.
Lina Madaniyazi et al.
Seasonality is a well-documented characteristic of many health outcomes, with mortality exhibiting distinct seasonal patterns due to environmental and demographic influences. While temperature is a key driver of these variations, additional...
Disrupted Tryptophan Metabolism Mediates Manganese-Induced Neurogenesis and Neuroinflammatory Impairments: Rescue by Exogenous Melatonin [0.03%]
外源性褪黑素可解救色氨酸代谢紊乱介导的锰致神经发生和神经炎症损伤作用
Xueting Wang,Teng Ma,Weifeng He et al.
Xueting Wang et al.
Manganese (Mn) is a common environmental pollutant, and excessive exposure can lead to motor dysfunction resembling Parkinson's disease. Increasing evidence suggests that Mn impairs endogenous neurogenesis and hinders neural repair. This st...
PM2.5 Induced Iron Accumulation-Associated Hepatocyte Toxicity and Mice Liver Injury via Activation of Ferroptosis and Pyroptosis [0.03%]
PM2.5诱导的铁蓄积相关肝细胞铁死亡和炎性坏死及其小鼠肝脏损伤效应
Weici Yan,Jianshu Wang,Yue Su et al.
Weici Yan et al.
Increasing evidence revealed a significant relationship between the fine particulate matter (PM2.5) exposure and the incidence of liver diseases. The contributions of ferroptosis and pyroptosis were recently reported in the progression of h...
Ozone Exposure Induces Anemia via Immune-Inflammatory Disruption of Erythroid Homeostasis [0.03%]
臭氧暴露通过免疫炎症干扰红细胞稳态诱导贫血
Yang Wang,Huifeng Yue,Nan Sang
Yang Wang
Ground-level ozone (O3), a major ambient air pollutant, is epidemiologically linked to anemia, but its mechanisms remain unclear. This study employed integrated phenotypic, histopathological, and transcriptomic analyses to explore the molec...
Microplastics and Nanoplastics Cause Thyroid Dysfunction in Adolescent Mice through the Intestinal Microbiota-Mediated Hypothalamus-Pituitary-Thyroid Axis [0.03%]
微塑料和纳米塑料通过肠道微生物群介导的下丘脑-垂体-甲状腺轴导致小鼠甲状腺功能障碍
Jinpeng Zhang,Jiaoyang Ji,Xiaowei Dai et al.
Jinpeng Zhang et al.
Polypropylene (PP) and poly-(ethylene terephthalate) (PET) plastic products are widely used in diet packaging and may generate microplastics (MPs) and nanoplastics (NPs) during use. However, their effects and mechanisms on causing endocrine...