Applications of Genome-wide Screening of CRISPR/Cas9 Knockout Library in Identifying Novel Molecular Targets for Xenobiotics [0.03%]
基于CRISPR/Cas9敲除文库的全基因组筛选在识别外源物新型分子靶标中的应用
Simin Lang,Xueyang Lin,Shengran Wang et al.
Simin Lang et al.
Pathogenic xenobiotics are ubiquitous in the environment. Environmental carcinogens induce mutations leading to tumors; pathogens relying on environmental media transmission cause infections; exposure to chemical or biological pollutants tr...
Cerebral to Systemic Representations of Alzheimer's Pathogenesis Stimulated by Polystyrene Nanoplastics [0.03%]
聚苯乙烯纳米塑料刺激的阿尔茨海默病病理发生从脑内到体内的演变
Yue Wang,Xiufang Liang,Nicholas Andrikopoulos et al.
Yue Wang et al.
Plastics discharged into the ecosphere can transform into micro- and nanoparticles to instigate interactions with biosystems, posing a threat to environmental sustainability and human health. While nanoplastics have recently been identified...
Enantioselective Modulation of Inflammatory Response through MAPK Pathway by Wavelike Chiral Nanoparticles [0.03%]
螺旋纳米粒子通过MAPK通路的手性选择性调节炎症反应
Yijin Tian,Jinghua Hao,Chao Lin et al.
Yijin Tian et al.
Infectious inflammation remains a major global health issue, so novel strategies to alleviate inflammatory responses are urgently required. Cinnabar (α-HgS) used in traditional Chinese medicine shows protective effects against inflammation...
Are "Clean" Days Really Clean? Single Particle Elemental Signatures of PM2.5 Unveil Their Pulmonary Health Risks [0.03%]
“清洁”空气日真的清洁吗？单颗粒元素示踪揭示PM2.5的肺健康风险
Mengyuan Wang,Zuoshun Niu,Xiaojing Yang et al.
Mengyuan Wang et al.
Ambient PM2.5 mass concentrations inadequately reflect health risks due to compositional heterogeneity. This study utilized single-particle inductively coupled plasma time-of-flight mass spectrometry (spICP-TOF-MS) to characterize high-reso...
Mia Sands,Yi Wen,Arshveer Sachdeva et al.
Mia Sands et al.
Perfluorooctanesulfonic acid (PFOS) is a persistent environmental pollutant widely present in ecosystems and humans, linked to numerous diseases, including cancers, due to its potent toxicity. Despite its harmful effects, effective strategi...
Oxidation Mechanism and Kinetics of γ‑Terpinene in the Indoor Atmosphere [0.03%]
γ-萜品烯在室内的氧化机理及动力学研究
Ahmad Jahanzab,Zihao Fu,Hui Zhao et al.
Ahmad Jahanzab et al.
γ-terpinene is widely used in personal care and household cleaning products. The gas-phase oxidation mechanism of γ-terpinene is essential for understanding its influence on atmospheric chemistry and its implications for human health. Uti...
Effects of Residential Greenness on Influenza Virus Infection in 1,012,430 People: A Nationwide Individual-Level Study in China [0.03%]
基于1012430人在中国的个体水平上的研究：居住地绿化对甲型流感病毒感染的影响
Shimeng Cai,Xin Liu,Lei Yang et al.
Shimeng Cai et al.
Residential greenness, a fundamental component of urban design, could contribute to the prevention of respiratory infections via several potential mechanisms. However, the health benefits of greenness on influenza epidemics in real world ar...
Exposure Levels and Health Risks of Phthalate Alternatives: A Urinary Metabolite Study [0.03%]
增塑剂替代品的暴露水平及健康风险：一种尿液代谢物研究
Jing Ren,Qingqing Zhu,Chunyang Liao et al.
Jing Ren et al.
Phthalate alternatives are increasingly replacing traditional phthalates (PAEs) as plasticizers due to growing regulatory and health concerns. However, these alternatives and their metabolites have been detected in both environmental and bi...
Long-Term Maternal Exposure to Triclosan Provokes Pulmonary Fibrosis in Mouse Offspring [0.03%]
长期接触三氯生致母鼠后代肺纤维化
Jing Liu,Mingzhu Guo,Wenqing Li et al.
Jing Liu et al.
Triclosan (TCS) is a broad-spectrum antibacterial agent that is widely used as an additive in personal care products. Due to its extensive application, TCS has been frequently detected in human samples, posing potential health risks. To inv...