The Association between Prenatal Quaternary Ammonium Compounds (QACs) Exposure and Neonatal Birth Obesity: Insights from Epidemiology and In Vitro Evidence [0.03%]
季铵化合物孕期暴露与新生儿出生过胖的相关性：流行病学和体外证据的新见解
Yongfeng Lin,Xiangyu Liu,Chunyan Deng et al.
Yongfeng Lin et al.
Quaternary ammonium compounds (QACs) are frequently used chemicals in consumer, medical, and personal care products that could be detected in blood samples from the general population. Cord blood samples are frequently employed in epidemiol...
A Critical Perspective on the Role of Thirdhand Smoke in Tumorigenesis: Initiator or Promoter [0.03%]
关于三手烟在肿瘤发生中的作用的批判性观点：启动物还是促进物？
Pin Wang,Xinyin Liu,Yankai Xia et al.
Pin Wang et al.
Thirdhand smoke (THS), lingering tobacco residues on surfaces and in dust after smoking, has emerged as a growing public health concern. While the carcinogenic risks of first- and secondhand smoke are well established, the tumorigenic poten...
Carboxyl Surface Modification Attenuates Polystyrene- but Not Poly(methyl methacrylate) Nanoplastic-Induced Gut Dysbiosis in Zebrafish Larvae [0.03%]
羧基表面修饰可减轻聚苯乙烯但不能减轻聚甲基丙烯酸甲酯纳米塑料对斑马鱼幼虫肠道微生物群的破坏作用
Eunbi Kwak,Shiqi Gai,Xueran Xu et al.
Eunbi Kwak et al.
Plastic polymers are widely recognized as significant environmental toxicants through their generation of nanoplastics (NPs), with polystyrene (PS) and poly-(methyl methacrylate) (PMMA) among the most frequently detected in ecosystems. Whil...
Gestational Arsenic Exposure Induces Metabolic Dysfunction-Associated Fatty Liver Disease-like Phenotypes in Middle-Aged Offspring [0.03%]
妊娠期砷暴露可诱发子代中年期非酒精性脂肪肝样病变
Qian-Qun Yang,Qing-Hua Qian,Wei-Wei Zhang et al.
Qian-Qun Yang et al.
Metabolic dysfunction-associated fatty liver disease (MAFLD) refers to hepatic steatosis accompanied by one of the following: type 2 diabetes, obesity, overweight, or metabolic dysfunction. Developmental arsenic (As) exposure is linked to m...
Exploring Toxicological Mechanisms of Typical PFAS-Induced NAFLD through Integrated Computational Toxicology and AOP Frameworks [0.03%]
基于计算毒理学和AOP框架的典型PFAS诱导的NAFLD毒性机制研究
Fei Li,Jin Wang,Yu Liu et al.
Fei Li et al.
As a typical endocrine disruptor, per- and polyfluoroalkyl substances (PFASs) are closely associated with the onset and progression of non-alcoholic fatty liver disease (NAFLD). However, research on the specific mechanism remains extremely ...
Risk Assessment of PFAS-Induced Male Reproductive Toxicity: A Comprehensive Evaluation Using the TRAEC Strategy [0.03%]
全氟和多氟烷基物质诱导雄性生殖毒性的风险评估：一种综合的TRAEC策略评价
Xiaoyu Xu,Ziye Xia,Junyao Luo et al.
Xiaoyu Xu et al.
Male fertility has declined rapidly in recent decades, a trend coinciding with increased environmental exposure pressures. Among these, perfluorinated and polyfluorinated alkyl substances (PFAS) have been reported to exert male reproductive...
AI-Enabled Mapping of Structure-Hazard Relationships for Emerging Contaminants [0.03%]
基于人工智能的新兴污染物结构风险关系映射模型
Shuo Zhang,Jun Guo,Yunkun Qian et al.
Shuo Zhang et al.
Emerging contaminant hazards are widespread, yet evidence is fragmented across the literature, registries, inventories, and bioassays. This study presents an integrated, reproducible framework that aligns literature-derived signals with mol...
Incomplete versus Sustained Innate-Immune Responses in the Medicinal Leech following Chronic, Environmentally Relevant Per- and Polyfluoroalkyl Substance Exposure [0.03%]
慢性接触全氟和多氟烷基物质对 медицинской мухоловки 免疫反应的影响
Nicolò Baranzini,Antonio Calisi,Gaia Marcolli et al.
Nicolò Baranzini et al.
Per- and polyfluoroalkyl substances (PFAS) persist in aquatic systems, yet hazard evaluations still rely largely on short-term tests. We chronically exposed the medicinal leech Hirudo verbana for two months to four PFAS congeners at 1 nmol ...
Long-Term Adverse Effects of Chlorinated Saline Primary Sewage Effluent and Halo-Nitrophenolic Disinfection Byproducts on a Marine Polychaete [0.03%]
氯化盐水初级污水排放物和卤代硝基苯酚消毒副产物对海洋环节动物的长期不利影响
Yu Li,Xiangru Zhang
Yu Li
The practice of flushing toilets with seawater in coastal cities can result in bromide- and iodide-rich saline sewage effluent, which generates brominated and iodinated aromatic disinfection byproducts (DBPs) with relatively high developmen...
Ambient Air Pollution and Hospital Admissions of AECOPD in 10 Regions of China: A Self-Controlled Study Based on a Cohort [0.03%]
中国10个城市急性加重期慢性阻塞性肺疾病的住院和空气污染：基于队列的自我控制病例系列研究
Lu Chen,Yuxuan Zhao,Jun Lv et al.
Lu Chen et al.
Gaps exist concerning the associations of PM2.5-10, gaseous pollutants, and composite pollutants with the acute exacerbation of chronic obstructive pulmonary disease (AECOPD). The interaction effects of lifestyle factors, indoor air polluti...