Tracing the In Vivo Fate of Polystyrene Nanoplastics via a Lanthanide Copolymerization Labeling Strategy [0.03%]
一种稀土共聚策略及微塑料在体内的代谢路径研究
Jiaqi Shen,Zhuda Song,Yun Wang et al.
Jiaqi Shen et al.
The widespread detection of plastic particles in environmental and biological matrices has raised health concerns, yet quantitative evidence on the in vivo behavior of submicron and nanoplastics (S/NPs) remains limited. Here, we developed a...
Antiviral Drugs in Wastewater-Based Epidemiology for Epidemic Surveillance and Alerting [0.03%]
废水溯源中的抗病毒药物用于疫情监控和预警研究
Bin Wang,Xiaogang Wang,Jiaqi Wen et al.
Bin Wang et al.
Wastewater-Based Epidemiology (WBE) has provided critical surveillance and alerting during epidemic outbreaks such as COVID-19 through viral nucleic acid detection, yet it faces limitations including a narrow short detection time window and...
Heatwaves, Cold Spells, and Renal Disease Mortality in Japan: Vulnerable Populations and Temporal Trends (1979-2019) [0.03%]
日本热浪与寒冷时期的肾脏疾病死亡率变化（1979-2019年）及脆弱人群分析
Zin Wai Htay,Chris Fook Sheng Ng,Yoonhee Kim et al.
Zin Wai Htay et al.
This study aims to investigate the short-term associations between heatwaves, cold spells, and renal disease mortality in Japan, focusing on temporal variations and identifying vulnerable populations. We obtained daily mortality counts for ...
Yi Zhang,Xin Meng,Jicheng Gong et al.
Yi Zhang et al.
High-altitude exposure poses significant health challenges, where microbial communities may serve as important contributors to host acclimatization. We conducted a longitudinal study to investigate the dynamic changes in pharyngeal and gut ...
Microcystin-LR Impairs Endometrial Receptivity during the Peri-Implantation Window via Disruption of STAT3/HIF-1α Signaling [0.03%]
微囊藻毒素-LR通过破坏STAT3/HIF-1α信号干扰植入窗期子宫内膜容受性
Yao Guo,Haohao Liu,Zongxin Zhang et al.
Yao Guo et al.
Microcystin-LR (MC-LR), an emerging contaminant present in aquatic environments, poses health risks owing to its widespread distribution, bioaccumulation potential, and well-documented human exposure. However, its impact on endometrial func...
Environmental Triggers and Ocular Disease Networks: Analyzing the Impact of Air Pollutants and Meteorological Factors Using Fuzzy Cognitive Maps [0.03%]
环境触发因素和眼部疾病网络：使用模糊认知图分析空气污染物和气象因素的影响
Li Zhang,Fabao Xu,Haixiang Jiang et al.
Li Zhang et al.
Growing evidence suggests that climate change and air pollution significantly contribute to the rising incidence of ocular morbidity; however, quantifying the complex interplay of these factors presents significant methodological challenges...
Effects of Antibiotic-Induced Gut Microbiota Dysbiosis on Arsenic Bioaccumulation and Transformation in Mice and Its Potential Mechanisms [0.03%]
抗生素引起的肠道菌群失调对小鼠体内砷积累和甲基化及其潜在机制的影响
Xiyan Jiang,Fang Zhao,Rui Li et al.
Xiyan Jiang et al.
The gut microbiota plays a crucial role in arsenic (As) metabolism, yet the extent of As metabolism under gut dysbiosis and the gut's response to As exposure remain lacking. This study used a mouse model with gut dysbiosis induced by cefope...
AHR: The Overlooked Mediator in SkincareBridging Environmental Sensing and Skin Physiology [0.03%]
被忽视的护肤介体AHR连接环境感知与皮肤生理学桥梁
Xiaoxu Hu,Ruihong Zhu,Yu Zhen et al.
Xiaoxu Hu et al.
The aryl hydrocarbon receptor (AHR) has expanded beyond its classical role and is increasingly recognized for its involvement in mediating the biological effects of cosmetic bioactives. Increasing evidence indicates that key cosmetic compou...
Temperature Variability and Chronic Obstructive Pulmonary Disease: The China Pulmonary Health Study [0.03%]
温度波动与慢性阻塞性肺疾病：中国肺健康研究
Hailu Zhu,Jisong Yan,Yicong Wang et al.
Hailu Zhu et al.
While the health effects of ambient temperature have been widely studied, temperature variability (TV), which is a critical aspect of climate change, has received limited attention. This study investigated the associations and potential med...
The Role and Mechanism of the cGAS-STING/NLRP3 Signaling Axis-Regulated p38 MAPK/NF-κB Pathway in Manganese-Induced Tau Aggregation-Mediated Neurotoxicity [0.03%]
cGAS-STING/NLRP3信号轴调控的p38MAPK/NF-κB通路在锰诱导Tau蛋白聚集介导的神经毒性中的作用和机制研究
Shiyin Zhong,Qiongli Zhou,Jirui Yang et al.
Shiyin Zhong et al.
Manganese (Mn) is an essential trace element, but increasing industrial and agricultural use has led to elevated levels of environmental Mn levels. Chronic overexposure to Mn can cause a Parkinson's-like neurodegenerative disorder; however,...