Association between Gestational Nitrated Polycyclic Aromatic Hydrocarbons Exposure Burden and Newborn Sizes: Mediating the Role of Placental 8‑OHdG [0.03%]
孕期多环芳烃硝基化代谢产物暴露与新生儿体格发育关系：胎盘氧化损伤的作用中介分析
Hao Xue,Chang Gao,Ruolan Wang et al.
Hao Xue et al.
Nitrated polycyclic aromatic hydrocarbons (nitro-PAHs) are persistent pollutants accompanying air pollution. No research has reported their exposure burden in pregnant women, nor is there epidemiological evidence of associations with newbor...
Assessing Nondietary Exposure to Per- and Polyfluoroalkyl Substances (PFASs) in Firefighters Using Silicone Wristbands [0.03%]
采用硅胶手环评估消防员中全氟和多氟化合物(PFASs)的非饮食暴露量
Taylor Hoxie,Sharon Zhang,Ellen M Cooper et al.
Taylor Hoxie et al.
Firefighters are uniquely exposed to per- and polyfluoroalkyl substances (PFASs) from use of aqueous film-forming foam (AFFF) and potentially from PFASs-treated turnout gear. This study assessed firefighter's ambient (nondietary) exposure t...
Exposure to Nanoplastics Disrupts Neurotransmitter Release in Rat Hippocampal Neurons [0.03%]
暴露于纳米塑料会扰乱大鼠海马神经元的神经递质释放
Ka Hei Ho,Xin Yi Yeo,Chungwon Park et al.
Ka Hei Ho et al.
Plastics are used broadly for various applications, and their degradation and fragmentation have led to widespread accumulation of nanoplastics in the environment. Although nanoplastics are ubiquitous and intractable in the environment and ...
Network Toxicology and In Vivo Studies Reveal the Toxicity and Mechanisms of Tributyl Citrate Carried by Microplastics in Promoting Colitis-to-Tumorigenesis Transformation [0.03%]
网络毒理学及体内研究揭示三丁基柠檬酸微塑料促进肠炎向肿瘤发生发展的毒性及其机制
Haosong Chen,Yixian Cheng,Yao Zhou et al.
Haosong Chen et al.
Tributyl citrate (TBC), a widely used substitute for phthalate plasticizers, has shown increasing environmental accumulation, raising concerns about its potential human health risks. However, its toxicological effects, particularly regardin...
The Role of Aryl Hydrocarbon Receptor-Dependent Signaling Pathway in the Profibrotic Effects of Dioxin-like Compounds in Human Renal Tubular Epithelial Cells [0.03%]
二恶英类似物促肾纤维化作用及与芳香烃受体信号途径关系的研究
Ruihong Zhu,Yiyun Liu,Xiaoxu Hu et al.
Ruihong Zhu et al.
The aryl hydrocarbon receptor (AhR) signaling pathway mediates nephrotoxic compound effects on the kidney, although its mechanisms are incompletely understood. Given that renal tubulointerstitial fibrosis is a central pathological feature o...
How Ambient Pollutants Accelerate Aging: Bridging Epigenetics, Age-Stratified Effects, and Public Health Interventions [0.03%]
环境污染如何加速衰老：表观遗传、年龄分层效应及公共卫生干预措施之间的桥梁研究
Ya-Qian Xu,Linghui Cai,Yaowen Nuo et al.
Ya-Qian Xu et al.
DNA Methylation of FAM50B/ PTCHD3 Mediates the Relationships between Low Blood Lead Exposure and Neurobehavioral Development of 0-3 Aged Infants: A Prospective Birth Cohort Study in Southern China [0.03%]
南方中国出生队列研究：DNA甲基化在FAM50B / PTCHD3介导血铅水平暴露与0-3岁婴幼儿神经行为发育关系中的作用
Cong Wan,Huimin Ma,Xiaowen Zeng et al.
Cong Wan et al.
Lead, recognized by the World Health Organization as one of the 10 chemicals of major public health concern, ranks as the fourth leading environmental risk factor contributing to the global burden of disease. Nevertheless, the neurodevelopm...
Health Risks of Prenatal and Early-Life Microplastics Exposure: A Comprehensive Review [0.03%]
孕期和生命早期暴露于微塑料的健康风险：全面综述
Haopeng Zhang,Xiaomeng Ding,Huijuan Zheng et al.
Haopeng Zhang et al.
Microplastics (MPs) and nanoplastics (NPs) are emerging environmental contaminants that have raised increasing concern regarding their potential health effects. During pregnancy and early life, developing organisms are particularly vulnerab...
Dynamic Associations between Ambient PM2.5 and Its Components and Transitions of Clinical Pregnancy and Adverse Reproductive Outcomes among Participants Treated with ART [0.03%]
空气中的PM2.5及其组分与接受辅助生殖技术治疗的参与者临床妊娠及不良生殖结局之间的动态关联
Zhonghua Ai,Yajun Dong,Xuefei Li et al.
Zhonghua Ai et al.
Evidence remains unknown regarding the associations between PM2.5 and its components exposure and dynamic progression of different assisted reproductive outcomes in participants undergoing fresh embryo transfer. We included infertile partic...
FTO-ACKR3 Axis Regulates Polycyclic Aromatic Hydrocarbons-Induced Asthma Attacks via AhR-Mediated m6A RNA Methylation [0.03%]
FTO-ACKR3轴通过AhR介导的m6A RNA甲基化调节多环芳烃诱导的哮喘发作
Shengbin Liu,Jiangzhou Chu,Jinxiu Xin et al.
Shengbin Liu et al.
Airborne polycyclic aromatic hydrocarbons (PAHs) are increasingly linked to asthma onset and exacerbation, yet their molecular mechanisms remain unclear. Building on our previous finding that PM2.5 alters m6A RNA methylation, we hypothesize...