Integrated transcriptomic and proteomic analysis reveals potential targets for heart regeneration [0.03%]
整合转录组和蛋白质组分析揭示心脏再生的潜在靶点
Liu Liu,Tongtong Yang,Qiqi Jiang et al.
Liu Liu et al.
Research on the regenerative capacity of the neonatal heart could open new avenues for the treatment of myocardial infarction (MI). However, the mechanism of cardiac regeneration remains unclear. In the present study, we constructed a mouse...
Impact of subchorionic hematoma on pregnancy outcomes in women with recurrent pregnancy loss [0.03%]
复发性流产女性妊娠期宫腔下血肿对妊娠结局的影响
Zijie Fu,Xuelei Ding,Dawei Wei et al.
Zijie Fu et al.
We conducted a retrospective cohort study with the aim of investigating the relationship between subchorionic hematoma (SCH) and pregnancy outcomes in women with recurrent pregnancy loss (RPL). We reviewed all RPL patients who came to the F...
Semir Vranic,Zoran Gatalica
Semir Vranic
Immunotherapy, based on immune checkpoint inhibitors targeting the Programmed cell death ligand 1 (PD-L1) and/or Programmed Death Receptor 1 (PD-1), has substantially improved the outcomes of patients with various cancers. However, only ~30...
Evolution of the combined effect of different irrigation solutions and activation techniques on the removal of smear layer and dentin microhardness in oval-shaped root canal: An in-vitro study [0.03%]
不同冲洗液及其激活技术联合使用对卵圆形根管内玷污层去除及牙本质硬度影响的演变：一项体外研究
Lu Shi,Jie Wan,Yunfei Yang et al.
Lu Shi et al.
The aim of this in vitro study was to evaluate the effect of three final irrigants, namely QMix, MTAD and EDTA, combined with three irrigation techniques, namely conventional needle irrigation (CNI), passive ultrasonic irrigation (PUI) and ...
Lejla Hadžikadić-Gušić,Timur Cerić,Inga Marijanović et al.
Lejla Hadžikadić-Gušić et al.
Breast cancer is the most common cancer among women. In Bosnia and Herzegovina, accurate data on the status of breast cancer are lacking due to the absence of a central registry. Multiple international guidelines imply that institutions tha...
Prediction of pathologic complete response prediction in patients with locally advanced esophageal squamous cell carcinoma treated with neoadjuvant immunochemotherapy: A real-world study [0.03%]
新辅助免疫化疗治疗局部晚期食管鳞状细胞癌患者病理完全缓解的预测：一项真实世界研究
Jifeng Feng,Liang Wang,Xun Yang et al.
Jifeng Feng et al.
As an emerging hotspot for patients with locally advanced esophageal squamous cell carcinoma (LA-ESCC), neoadjuvant immunochemotherapy (nICT) is safe and feasible. Pathological complete response (pCR) is considered to be an important therap...
Autophagy attenuates osteoarthritis in mice by inhibiting chondrocyte pyroptosis and improving subchondral bone remodeling [0.03%]
自噬通过抑制软骨细胞焦亡和改善骨下骨重塑来缓解小鼠骨关节炎
Jiangbo Yan,Gangning Feng,Yong Yang et al.
Jiangbo Yan et al.
Osteoarthritis (OA) is an age-related degenerative disease characterized by cartilage degeneration and abnormal bone remodeling in the subchondral bone. Autophagy maintains cellular homeostasis by self-phagocytosis. However, the underlying ...
Risk of graft loss in kidney transplant recipients after aortic valve replacement [0.03%]
肾移植受者主动脉瓣置换术后移植物丢失的风险
Stefan Büttner,Carolin Zöller,Sammy Patyna et al.
Stefan Büttner et al.
Surgical aortic valve replacement (SAVR) in kidney transplant recipients (KTR) is associated with high morbidity and mortality, and an increased risk of postoperative graft failure potentially leading to graft loss. Transcatheter aortic val...
Olanzapine decreased osteocyte maturation and Wnt/β-catenin signaling during loading of the alveolar bone in rats [0.03%]
奥氮平通过下调Wnt/β-联蛋白信号影响大鼠牙槽骨应变成熟型成骨细胞的比例
Saranda Disha-Ibrahimi,Borut Furlani,Gorazd Drevenšek et al.
Saranda Disha-Ibrahimi et al.
Several studies indicate the influence of olanzapine on bone metabolism; however, the results are contradictory. We evaluated the effects of olanzapine on the Wnt/β-catenin signaling pathway, physiological alveolar bone turnover, and alveo...