Machine learning for predicting the survival in osteosarcoma patients: Analysis based on American and Hebei Province cohort [0.03%]
基于美国和河北省队列的儿童骨肉瘤预后机器学习模型研究
Yahui Hao,Di Liang,Shuo Zhang et al.
Yahui Hao et al.
Osteosarcoma, a rare malignant tumor, has a poor prognosis. This study aimed to find the best prognostic model for osteosarcoma. There were 2912 patients included from the SEER database and 225 patients from Hebei Province. Patients from th...
Exogenous spermidine alleviates diabetic cardiomyopathy via suppressing reactive oxygen species, endoplasmic reticulum stress, and Pannexin-1-mediated ferroptosis [0.03%]
外源性腐胺通过抑制活性氧、内质网应激和Pannexin-1介导的铁死亡来缓解糖尿病心肌病
Jian Sun,Jiyu Xu,Yong Liu et al.
Jian Sun et al.
Diabetic cardiomyopathy (DCM) is a serious complication and death cause of diabetes mellitus (DM). Recent cardiology studies suggest that spermidine (SPD) has cardioprotective effects. Here, we verified the hypothesis of SPD's protective ef...
Xiangming Meng,Chengzhou Han,Yangyang Wang
Xiangming Meng
The COVID-19 pandemic has caused substantial population infections worldwide. COVID-19 has been reported to cause acute epiglottitis (AE); nonetheless, COVID-19-related AE is poorly understood by healthcare workers because of the disease's ...
Increased co-expression of TIM-3 with TIGIT or 2B4 on CD8+ T cells is associated with poor prognosis in locally advanced nasopharyngeal carcinoma [0.03%]
CD8⁺ T细胞中TIM-3与TIGIT或2B4共表达增加与局部晚期鼻咽癌预后不良相关
Xiaolin Xie,Yaning Feng,Peiwen Fan et al.
Xiaolin Xie et al.
The use of immune checkpoint inhibitors in malignant tumors improves patient outcomes. Because single-agent immune checkpoint blockade has a low objective response rate, it is meaningful to explore combined blockade of immune checkpoint rec...
IGHG1 promotes malignant progression in breast cancer cells through the regulation of AKT and VEGF signaling [0.03%]
IGHG1通过调节AKT和VEGF信号促进乳腺癌细胞恶性进展
Yong Zhang,Xueying Fang,Yan Sun
Yong Zhang
Immunoglobulin heavy constant chain gamma 1 (IGHG1) is highly expressed in a variety of cancers and is considered an emerging prognostic marker. Overexpression of IGHG1 in breast cancer tissues has also been demonstrated, but an in-depth an...
Is hepatic resection always a better choice than radiofrequency ablation for solitary hepatocellular carcinoma regardless of age and tumor size? [0.03%]
肝癌的射频消融与切除术的优选性不受年龄及肿瘤大小的影响？
Shicong Zeng,Yao Zhang,Zongwen Wang et al.
Shicong Zeng et al.
In this study, we aimed to compare survival outcomes after receiving radiofrequency ablation (RFA) and hepatic resection (HR) for solitary hepatocellular carcinoma (HCC) with stratification by tumor size and age. A retrospective cohort was ...
Echocardiographic and hemodynamic changes in patients with high-grade varicocele [0.03%]
高位精索静脉曲张患者的超声心动图和血流动力学变化
Batuhan Ergani,Azmi Eyiol,Mustafa Karabiçak et al.
Batuhan Ergani et al.
Varicocele is abnormal tortuosity and dilatation of the pampiniform plexus veins within the spermatic cord. Varicocele is associated with testicular atrophy, hypogonadism, impaired semen analysis values, or decreased testosterone production...
The role of Rapsyn in neuromuscular junction and congenital myasthenic syndrome [0.03%]
Rapsyn在神经肌肉接头及先天性肌无力综合征中的作用
Xufeng Liao,Yingxing Wang,Xinsheng Lai et al.
Xufeng Liao et al.
Rapsyn, an intracellular scaffolding protein associated with the postsynaptic membranes in the neuromuscular junction (NMJ), is critical for nicotinic acetylcholine receptor clustering and maintenance. Therefore, Rapsyn is essential to the ...
Etiology and clinical features of non-O1/non-O139 Vibrio cholerae infection in an inland city in China [0.03%]
中国内地城市非O1群/非O139霍乱弧菌感染的流行特征及临床特点
Yu-Han Xiang,Qin-Qin Hu,Yan Liu et al.
Yu-Han Xiang et al.
Non-O1/non-O139 Vibrio cholerae (NOVC) causes various illnesses ranging in severity from mild to life-threatening but were ignored previously. Knowledge of the NOVC infection, particularly bacteremia, is limited because of its rarity. Here ...
Myocarditis and coronavirus disease 2019 vaccination: A systematic review and meta-summary of cases [0.03%]
心肌炎和新型冠状病毒疾病2019年疫苗接种：病例的系统评价和元总结
Pandit Bagus Tri Saputra,Roy Bagus Kurniawan,Desy Trilistyoati et al.
Pandit Bagus Tri Saputra et al.
Vaccination is significant to control, mitigate, and recover from the destructive effects of coronavirus disease 2019 (COVID-19). The incidence of myocarditis following COVID-19 vaccination has been increasing and growing public concern; ho...