SKIL/SnoN attenuates TGF-β1/SMAD signaling-dependent collagen synthesis in hepatic fibrosis [0.03%]
SKIL/SnoN通过抑制TGF-β1/SMAD信号通路依赖性胶原合成抗肝纤维化作用
Cheng Chi,Xifeng Liang,Tianyu Cui et al.
Cheng Chi et al.
The ski-related novel gene (SnoN), encoded by the SKIL gene, has been shown to negatively regulated transforming growth factor-β1 (TGF-β1) signaling pathway. However, the roles of SnoN in hepatic stellate cell (HSC) activation and hepatic...
The roles of trimethylamine-N-oxide in atherosclerosis and its potential therapeutic aspect: A literature review [0.03%]
三甲胺氮氧化物在动脉粥样硬化中的作用及其潜在治疗意义：文献回顾
Yudi Her Oktaviono,Ariikah Dyah Lamara,Pandit Bagus Tri Saputra et al.
Yudi Her Oktaviono et al.
Current research supports the evidence that the gut microbiome (GM), which consist of gut microbiota and their biologically active metabolites, is associated with atherosclerosis development. Trimethylamine-N-oxide (TMAO), a metabolite prod...
Deciphering transcriptional dynamics of cardiac hypertrophy and failure in a chamber-specific manner [0.03%]
以室腔特异性方式解读心脏肥大和衰竭的转录动力学
Dan Zhang,Jianming Liu,Haiying Xiao et al.
Dan Zhang et al.
Pressure overload-induced pathological cardiac hypertrophy (CH) is a complexed and adaptive remodeling of the heart, predominantly involving an increase in cardiomyocyte size and thickening of ventricular walls. Over time, these changes can...
ABO gene polymorphisms are associated with acute coronary syndrome and with plasma concentration of HDL-cholesterol and triglycerides [0.03%]
ABO基因多态性与急性冠脉综合征以及血浆HDL胆固醇和甘油三酯浓度相关性研究
Gilberto Vargas-Alarcón,Oscar Pérez-Méndez,Rosalinda Posadas-Sánchez et al.
Gilberto Vargas-Alarcón et al.
The role of ABO gene polymorphisms in acute coronary syndrome (ACS) and lipid metabolism is increasingly recognized. We investigated whether ABO gene polymorphisms are significantly associated with ACS and the plasma lipid profile. Six ABO ...
Lingyuan He,Mengchen Shi,Shuwei Ren et al.
Lingyuan He et al.
Apolipoprotein E (apoE) has previously been reported to play vital roles in tumor progression. However, the impact of apoE on colorectal cancer (CRC) metastasis remains largely unexplored. This study aimed to investigate the role of apoE in...
Alcoholic extracts of Teucrium polium exhibit remarkable anti-inflammatory activity: In vivo study [0.03%]
Teucrium polium的醇提物具有显著的抗炎活性：体内实验研究
Hamda A Al-Naemi,Reem Moath Alasmar,Kaltham Al-Ghanim
Hamda A Al-Naemi
Teucrium polium (germander, Lamiaceae) is a local plant in Qatar that has been used in folk medicine to treat numerous illnesses. It is known for its antioxidant, analgesic, anticancer, and antibacterial activities. This study aimed to eval...
Prognostic factors for regorafenib treatment in patients with refractory metastatic colorectal cancer: A real-life retrospective multi-center study [0.03%]
regorafenib治疗难治性转移性结直肠癌患者预后因素的回顾性多中心研究
Sabin Goktas Aydin,Engin Eren Kavak,Atakan Topcu et al.
Sabin Goktas Aydin et al.
Regorafenib, an oral multikinase inhibitor, has improved survival in metastatic colorectal cancer (mCRC) patients who have progressed on standard therapies. Our study aimed to evaluate prognostic factors influencing regorafenib treatment an...
Multicenter Study
Biomolecules & biomedicine. 2023 Nov 3;23(6):1089-1095. DOI:10.17305/bb.2023.9253 2023
A novel autophagy-related subtypes to distinguish immune phenotypes and predict immunotherapy response in head and neck squamous cell carcinoma [0.03%]
一种新的自噬相关亚型可区分免疫表型并预测头颈鳞癌的免疫治疗反应
Bo Ma,Hui Li,Mingzhu Zheng et al.
Bo Ma et al.
Both the absence of autophagy and excessive autophagy is double-edged sword in tumorigenesis. Due to the specificity of autophagy, its role in head and neck squamous cell carcinoma (HNSCC) is still unclear. In this study, we established fiv...
Analysis of GPR126 polymorphisms and their relationship with scoliosis in Marfan syndrome and Marfan-like syndrome in Mexican patients [0.03%]
墨西哥患者中GPR126多态性与马凡综合征及类马凡综合征背痛和脊柱侧弯的关系分析
Maria Elena Soto,Giovanny Fuentevilla-Alvarez,Solange Gabriela Koretzky et al.
Maria Elena Soto et al.
Marfan syndrome (MFS) is an inherited connective tissue disorder. As the spinal growth depends on delicate balance of forces, conditions that affect musculoskeletal matrix often lead to spinal deformities. A large cross-sectional study reve...
Cytoplasmic amino acid profiles of clinical and ATCC 29213 strains of Staphylococcus aureus harvested at different growth phases [0.03%]
不同生长期收获的临床和ATCC 29213菌株金黄色葡萄球菌细胞质氨基酸轮廓图
Mousa Alreshidi,Hugh Dunstan,Tim Roberts et al.
Mousa Alreshidi et al.
Staphylococcus aureus strains are a great contributor to both hospital acquired infections as well as community acquired infections. The objective of the present investigation was to compare potential differences in cytoplasmic amino acid l...