CCNI2 promotes pancreatic cancer through PI3K/AKT signaling pathway [0.03%]
CCNI2通过PI3K/AKT信号通路促进胰腺癌发生發展
Bingyang Hu,Wenzhi Zhang,Changsheng Zhang et al.
Bingyang Hu et al.
Globally, pancreatic cancer is recognized as one of the deadliest malignancies that lacks effective targeted therapies. This study aims to explore the role of cyclin I-like protein (CCNI2), a homolog of cyclin I (CCNI), in the progression o...
Identification of potential hub genes associated with atopic dermatitis-like recombinant human epidermal model using integrated transcriptomic and proteomic analysis [0.03%]
利用整合转录组学和蛋白质组学分析鉴定与特应性皮炎类似的人类重建表皮模型相关的重要基因
Wu Qiao,Tong Xie,Jing Lu et al.
Wu Qiao et al.
Atopic dermatitis (AD) is a severe inflammatory skin disorder, characterized by elevated levels of proinflammatory cytokines that fuel a vicious cycle of inflammation. While inflammatory recombinant human epidermal (RHE) models relevant to ...
Jianbin Li,Yiping Huang,Yueqin Zhang et al.
Jianbin Li et al.
Sphingosine-1-phosphate (S1P) is a versatile sphingolipid that is generated through the phosphorylation of sphingosine by sphingosine kinase (SPHK). S1P exerts its functional effects by binding to the G protein-coupled S1P receptor (S1PR). ...
Dynamic changes in lactate levels within the first 24 hours in septic patients as a prognostic indicator: A retrospective cohort study utilizing latent class growth analysis [0.03%]
利用潜在类增长分析的回顾性队列研究中的重症患者入院后前24小时乳酸水平变化的预后价值
Shifeng Li,Tao You,Meili Liu et al.
Shifeng Li et al.
Elevated lactate levels are common in sepsis patients. This study aimed to assess the effect of dynamic changes in lactate levels within the first 24 hours following admission on patient prognosis. We extracted data from the Medical Informa...
Clinical features and demographic characteristics of gestational trophoblastic neoplasia: Single center experience and the SEER database [0.03%]
妊娠期滋养细胞肿瘤的临床特点和人口统计学特征：单中心经验与SEER数据库研究
Yue-Min Hou,Pei-Pei Li,Hui Yu et al.
Yue-Min Hou et al.
The aim of this study was to analyze the clinical features and demographic characteristics of gestational trophoblastic neoplasia (GTN) patients, specifically choriocarcinoma (CC), placental site trophoblastic tumour (PSTT), and epithelioid...
Potential susceptibility genes in patients with stage III and IV periodontitis: A whole-exome sequencing pilot study [0.03%]
三期和四期牙周病患者的潜在易感基因：全外显子测序初步研究
Fan Xue,Jianjiang Zhao,XiaoCui Gao et al.
Fan Xue et al.
The aim of this study was to screen potential susceptibility genes using whole-exome sequencing (WES) in 15 Han Chinese patients with stage III or IV periodontitis and to evaluate the quantity and quality of genomic DNA extracted from saliv...
Gaining consensus on expert rule statements for acute respiratory failure digital twin patient model in intensive care unit using a Delphi method [0.03%]
使用德尔菲法在重症监护室达成急性呼吸衰竭数字孪生患者模型专家规则语句的共识
Amy J Montgomery,John Litell,Johnny Dang et al.
Amy J Montgomery et al.
Digital twin technology is a virtual depiction of a physical product and has been utilized in many fields. Digital twin patient model in healthcare is a virtual patient that provides opportunities to test the outcomes of various interventio...
Biosurfactant derived from probiotic Lactobacillus acidophilus exhibits broad-spectrum antibiofilm activity and inhibits the quorum sensing-regulated virulence [0.03%]
源自益生菌乳酸杆菌的生物表面活性剂具有广谱抗生物膜活性并抑制群体感应调节的毒力
Mohd Adnan,Arif Jamal Siddiqui,Emira Noumi et al.
Mohd Adnan et al.
Antimicrobial resistance by pathogenic bacteria has become a global risk to human health in recent years. The most promising approach to combating antimicrobial resistance is to target virulent traits of bacteria. In the present study, a bi...
Changes in inflammatory responses and autophagy during apheresis platelet preservation and their correlation with platelet transfusion refractoriness in patients with acute lymphoblastic leukemia [0.03%]
血液分离机保存血小板炎症反应及自噬的变化及其与急性淋巴细胞白血病患者输注后血小板输注无效的相关性研究
Ying Li,Zhiqun Song,Xiaohong Sun et al.
Ying Li et al.
Acute lymphoblastic leukemia (ALL) is a common hematopoietic malignancy, and platelet transfusion plays a crucial role in its treatment. This study aimed to investigate the changes in inflammatory response and autophagy during the preservat...
Molecular classification of muscle-invasive bladder cancer based on a simplified immunohistochemical panel using GATA3, CK5/6 and p16 [0.03%]
基于简化免疫组化标记GATA3、CK5/6和p16的肌层浸润性膀胱癌分子分型研究
Robert Terlević,Monika Ulamec,Goran Štimac et al.
Robert Terlević et al.
The choice of therapy for muscle-invasive bladder cancer (MIBC) could be influenced by the tumor's molecular subtype. Currently, well-defined consensus subtypes are based on tumor microarray mRNA data. Clearly defined and easy-to-use surrog...