A novel machine learning-derived four-gene signature predicts STEMI and post-STEMI heart failure [0.03%]
一种新颖的机器学习衍生四基因标志物可预测STEMI和STEMI后心力衰竭
Jialu Yao,Yujia Zhou,Zhichao Yao et al.
Jialu Yao et al.
High mortality and morbidity rates associated with ST-elevation myocardial infarction (STEMI) and post-STEMI heart failure (HF) necessitate proper risk stratification for coronary artery disease (CAD). A prediction model that combines speci...
Sugammadex and urinary retention after hysterectomy: A propensity-matched cohort study [0.03%]
sugammadex术后子宫切除术与尿潴留：倾向匹配队列研究
Mariana L De Lima Laporta Miranda,Michelle A Ochs Kinney,Jamie N Bakkum-Gamez et al.
Mariana L De Lima Laporta Miranda et al.
Postoperative urinary retention (POUR) is a well-known complication after gynecologic surgery. Our objective was to investigate whether the choice of pharmacologic agent for reversing neuromuscular blockade at the end of a hysterectomy is a...
The laboratory parameters in predicting the severity and death of COVID-19 patients: Future pandemic readiness strategies [0.03%]
实验室参数在预测COVID-19患者严重程度和死亡率方面的应用：未来大流行应对策略
Ahmad R Alsayed,Syed Imran Ahmed,Anas Osama Al Shweiki et al.
Ahmad R Alsayed et al.
The range of clinical manifestations associated with the infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) encompasses a broad spectrum, ranging from flu-like symptoms to the occurrence of multiple organ failure ...
Clinical characteristics associated with recurrent viral RNA positivity in patients within two weeks after recovering from the first SARS-CoV-2 infection [0.03%]
初次感染新冠病毒恢复后两周内病毒RNA复发的临床特征分析研究
Xi Cao,Yongli Xie,Chunlei Zhou et al.
Xi Cao et al.
Many studies have shown that recovered coronavirus disease 2019 (COVID-19) patients frequently exhibit recurrent viral RNA positivity (RP) for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Our study aimed to summarize th...
The usefulness of the genetic panel in the classification and refinement of diagnostic accuracy of Mexican patients with Marfan syndrome and other connective tissue disorders [0.03%]
基因谱系在马凡综合征及其他结缔组织病的墨西哥患者的分类和诊断精度改进中的作用
Giovanny Fuentevilla-Álvarez,María Elena Soto,Yazmín Estela Torres-Paz et al.
Giovanny Fuentevilla-Álvarez et al.
Marfan syndrome (MFS) is a multisystem genetic disorder with over 3000 mutations described in the fibrillin 1 (FBN1) gene. Like MFS, other connective tissue disorders also require a deeper understanding of the phenotype-genotype relationshi...
Comprehensive analysis of a NAD+ metabolism-derived gene signature to predict the prognosis and immune landscape in endometrial cancer [0.03%]
全面分析NAD+代谢衍生的基因特征以预测子宫内膜癌的预后和免疫图谱
Dan Hu,JunHong Du,YueMei Cheng et al.
Dan Hu et al.
As a crucial regulator influencing tumor progression, nicotinamide adenine dinucleotide (NAD+) is widely acknowledged. However, its role in endometrial cancer (EC) is not completely understood. In this study, we aimed to develop an NAD+meta...
Downregulation of SIRT1 and GADD45G genes and left atrial fibrosis induced by right ventricular dependent pacing in a complete atrioventricular block pig model [0.03%]
右室起搏导致完全性房室传导阻滞猪模型中心肌SIRT1和GADD45G基因下调及左心房纤维化诱导
Wei-Chieh Lee,Yu-Sheng Lin,Man-Jing Chen et al.
Wei-Chieh Lee et al.
The molecular and genetic mechanisms underlying left atrial (LA) enlargement and atrial fibrosis following right ventricular (RV) dependent pacing remain unclear. Our objective was to investigate genetic expressions in the LA of pigs subjec...
Stem cell therapy for degenerative disc disease: Bridging the gap between preclinical promise and clinical potential [0.03%]
干细胞治疗退行性椎间盘疾病：跨越从临床前前景到临床潜力的鸿沟
Matic Munda,Tomaz Velnar
Matic Munda
Stem cell therapy has gained attention in the field of regenerative medicine due to its potential to restore damaged tissue. This article focuses on the application of stem cell therapy for treating spinal pathologies, particularly interver...
Meta-analysis of changes in thiol-disulfide homeostasis during preeclampsia [0.03%]
硫醇-硫化物平衡在子痫前期发病期间的变化的meta分析研究
Dan Wang,Guihong Yang,Xinxin You et al.
Dan Wang et al.
The present study systematically assessed alterations in thiol-disulfide homeostasis among women with preeclampsia (PE) through meta-analysis. This was conducted as such changes are believed to be associated with the oxidative stress underl...
Beyond hot flashes: Exploring the role of estrogen therapy in postmenopausal women for myocardial infarction prevention and recovery [0.03%]
绝经后妇女雌激素治疗的心肌梗死防治作用探究——绝经后的症状不仅限于潮热
Akash Choradia,Karoona Bai,Suha Soni et al.
Akash Choradia et al.
Myocardial infarction (MI) commonly known as "heart attack" results from the blockage of blood flow to the heart. Postmenopausal women face an elevated risk of MI due to declining estrogen levels, a hormone pivotal in maintaining cardiovasc...