Morphine-induced hepatotoxicity in rats: Sex and dose variations in liver enzymes, oxidative stress, inflammation, apoptosis, and histopathology [0.03%]
吗啡致大鼠肝毒性：肝脏酶、氧化应激、炎症、凋亡和组织学的性别和剂量差异
Olaoluwa Sesan Olukiran,Oluwole Ojo Alese,Oluwadare Joshua Ogundipe et al.
Olaoluwa Sesan Olukiran et al.
Drug-induced liver injury is a significant cause of acute liver failure, and sex-related biological differences may affect hepatic responses to xenobiotics. This study examined the sex- and dose-dependent effects of morphine on liver functi...
Butyl and isobutyl ortho-coumaric acid derivatives reduce self-renewal and MGMT expression in GBM cells with stem cell-like characteristics in vitro [0.03%]
丁基和异丁基邻香豆酸衍生物通过下调MGMT表达抑制体外胶质母细胞瘤干细胞样细胞的自我更新能力
Luis Javier Reséndiz-Castillo,Yanet Karina Gutiérrez-Mercado,Juan Carlos Mateos-Díaz et al.
Luis Javier Reséndiz-Castillo et al.
Ortho-coumaric acid (o-CA) derivatives, specifically butyl, isobutyl, propyl, ethyl, and methyl-o-coumarate, have emerged as potential therapeutic agents for glioblastoma multiforme (GBM). This study investigates their effects on drug resis...
ZNF469 drives TGF-β1/SMAD3-mediated extracellular matrix regulation in pulmonary fibrosis [0.03%]
ZNF469通过TGF-β1/SMAD3介导的细胞外基质调节驱动肺纤维化发展
Thammachanok Boonto,Nucharnart Suntornnont,Archittapon Nokkeaw et al.
Thammachanok Boonto et al.
Pulmonary fibrosis is characterized by persistent activation of lung fibroblasts and excessive extracellular matrix (ECM) deposition; however, the transcriptional mechanisms sustaining this activated state remain poorly understood. Given th...
Neutrophil-to-lymphocyte ratio as a prognostic biomarker in lung cancer patients treated with PD-1/PD-L1 inhibitors: A systematic review and meta-analysis [0.03%]
中性粒细胞与淋巴细胞比值在PD-1/PD-L1抑制剂治疗肺癌患者中的预后价值：系统评价和Meta分析
Yong Zeng,Junlin Gu,Weiqiong Chen et al.
Yong Zeng et al.
Lung cancer (LC) continues to be a leading cause of cancer-related mortality, highlighting the need for reliable and accessible biomarkers to identify patients at higher risk of poor outcomes during immunotherapy. This systematic review and...
Meta-Analysis
Biomolecules & biomedicine. 2026 May 28. DOI:10.17305/bb.2026.14145 2026
CAR-T cell therapy in cancer immunotherapy - Biology, clinical successes, and emerging challenges: A review [0.03%]
癌症免疫治疗中的CAR-T细胞治疗-生物学，临床成功与新兴挑战：综述论文
Abdisa Tufa Bedada,Mohammed Mehdi,Ousman Mohammed
Abdisa Tufa Bedada
Cancer immunotherapy has transformed oncology by enabling targeted activation of antitumor immune responses in patients with relapsed or refractory malignancies. Among adoptive cell transfer (ACT) strategies, chimeric antigen receptor T-cel...
Clitoria ternatea and Moringa oleifera extracts reduce endothelial activation and intimal thickening in diet-induced atherosclerosis [0.03%]
藤叶和鼓槌树提取物可减少饮食诱导的动脉粥样硬化中的内皮活化和内膜增厚
Karnirius Harefa,Ahmad Hafizullah Ritonga,Riri Safitri et al.
Karnirius Harefa et al.
Atherosclerosis is a chronic inflammatory vascular disease characterized by endothelial activation and progressive thickening of the tunica intima. This study aimed to evaluate the effects of combined Clitoria ternatea and Moringa oleifera ...
NIHSS and inflammatory biomarkers predict 90-day poor outcome in older patients with acute ischemic stroke [0.03%]
NIHSS和炎症生物标志物可预测急性缺血性卒中老年患者的90天不良预后
Chunlan Hou,Qianwei Zheng,Zilong Yang et al.
Chunlan Hou et al.
Early prediction of functional outcomes following acute ischemic stroke (AIS) in older adults presents significant clinical challenges. Inflammation-related biomarkers may enhance clinical severity scores for early risk stratification. This...
Human Tsukamurella infections - Clinical spectrum, diagnosis, antimicrobial resistance, and treatment outcomes: A review [0.03%]
人类.tsukamurella感染：临床表现、诊断、抗菌药物耐药性及治疗效果综述
Bandar Hasan Saleh,Sulaiman Bani Abdel-Rahman,Hala Altarawneh et al.
Bandar Hasan Saleh et al.
Tsukamurella species are rare environmental aerobic actinomycetes that are increasingly recognized as opportunistic human pathogens, particularly among immunocompromised patients and those with indwelling medical devices. This review aims t...
Comparative performance of APACHE II, SOFA, and Charlson Comorbidity Index in sepsis mortality prediction [0.03%]
APACHE II、SOFA和Charlson合并症指数在预测脓毒症患者死亡率方面的比较性能
Srdjan Gavrilovic,Nikola Drincic Stipic,Milica Vasilic et al.
Srdjan Gavrilovic et al.
Sepsis remains a leading cause of mortality in intensive care units (ICUs) globally; however, the effectiveness of conventional prognostic scoring systems varies across healthcare settings and patient populations. This study aimed to evalua...
Dental management of oral adverse effects associated with immune checkpoint inhibitors: A review [0.03%]
免疫检查点抑制剂相关口腔不良反应的牙科处理综述
Andra Piciu,Andrei Tent,Dacian Sabau et al.
Andra Piciu et al.
Cancer immunotherapy, particularly immune checkpoint inhibitors (ICIs) that target programmed cell death protein 1 (PD-1), programmed death-ligand 1 (PD-L1), and cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4), has significantly advanc...