Natural products modulate social behavior and gut microbiota in a valproic acid-induced zebrafish model of autism spectrum disorder [0.03%]
天然产物调节孤独症谱系障碍瓦勒帕尔酸诱导斑马鱼模型的社会行为和肠道微生物群
Oana-Georgiana Oprea,Ioana-Miruna Balmus,Tudor Ilie et al.
Oana-Georgiana Oprea et al.
Natural products rich in honey- and plant-derived bioactive compounds are increasingly investigated as modulators of the gut-brain-microbiome axis, a pathway implicated in autism spectrum disorder (ASD)-related behavioral and gastrointestin...
LODDS-based nomogram for breast cancer-specific survival in surgically treated young breast cancer [0.03%]
基于LODDS的年轻乳腺癌手术患者乳腺癌特异性生存预测列线图
Ziqiang Wang,Zhenlin Yang,Haojie Zhang
Ziqiang Wang
Traditional tumor staging relies on absolute lymph node counts, making it susceptible to stage migration, particularly in young breast cancer (YBC) patients with aggressive disease. This study assessed the prognostic value of the continuous...
Leukocyte cell population data predict 30-day mortality in community-acquired pneumonia: A multicenter prospective study [0.03%]
社区获得性肺炎的住院患者的白细胞群体数据可预测其30天死亡率：一项多中心前瞻性研究
Ane Uranga,Eloísa Urrechaga,Urko Aguirre et al.
Ane Uranga et al.
Early identification of patients with community-acquired pneumonia (CAP) at increased risk of death remains essential, but rapid and low-cost prognostic biomarkers are still needed. Cell population data (CPD), automatically generated during...
Breast cancer response to neoadjuvant chemotherapy: Pre-treatment NLR, PLR, LMR, and SII do not predict pathological complete response or residual cancer burden [0.03%]
新辅助化疗乳腺癌患者的临床完全缓解与残留病灶负荷：术前NLR、PLR、LMR和SII无预测价值
İsmail Zİhnİ,Mehmet Zafer Sabuncuoğlu,Burcu Zİhnİ et al.
İsmail Zİhnİ et al.
Inflammation-based indices, derived from routine complete blood count parameters such as the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), and systemic immune-inflammation inde...
Advanced glycation end product accumulation and AGEs-RAGE axis biomarkers in plasma and synovial fluid are associated with osteoarthritis severity [0.03%]
血浆和滑液中晚期糖基化终末产物蓄积及AGEs-RAGE轴生物标志物与骨关节炎严重程度相关性研究
Anja Šoštarič,Iza Oblak,Dušan Šuput et al.
Anja Šoštarič et al.
Osteoarthritis (OA) is a common whole-joint degenerative disease characterized by cartilage degradation, subchondral bone remodeling, synovial inflammation, and incompletely understood molecular mechanisms. Advanced glycation end products (...
Hantaviruses in Southeast Europe: Climate change, rodent reservoirs, and One Health challenges [0.03%]
南欧汉坦病毒：气候变迁、宿主动物和“同一个健康”的挑战
Jurica Arapović,Luka Laura,Maja Arapović
Jurica Arapović
Hantaviruses are not emerging pathogens in the strict sense, but their public health relevance is being reshaped by climate change, environmental disruption, land-use change, and increasing human mobility. In Southeast Europe, where Dobrava...
Prognostic value of preoperative mGPS, CAR, and NLR in patients undergoing resection for non-small cell lung cancer [0.03%]
术前mGPS、CAR和NLR对非小细胞肺癌手术患者的预后价值
Mehmet Mermer,Hıdır Esme
Mehmet Mermer
Systemic inflammation is increasingly recognized as a crucial prognostic factor in non-small cell lung cancer (NSCLC). However, comprehensive evaluations comparing multiple inflammation-based indices in surgically treated cohorts, especiall...
Coronary artery calcium and multiparametric cardiovascular risk assessment in non-dialysis chronic kidney disease [0.03%]
慢性肾病患者冠状动脉钙化与多参数心血管风险评估
Ivana Đuran,Nikola Komazec,Bojana Ljubičić et al.
Ivana Đuran et al.
Cardiovascular disease is a leading cause of mortality in chronic kidney disease (CKD), but whether impaired renal function independently increases coronary artery calcium (CAC) burden in patients with comparable cardiovascular referral ind...
Reclassification of BRCA1 variants of uncertain significance using ancestry-stratified allele frequencies: A Middle East-focused analysis [0.03%]
利用不同祖先背景的等位基因频率对BRCA1意义未明变异进行再分类：以中东人群为重点的分析
Lama Abujamous,Rozaimi Razali,Hamda Al-Thawadi
Lama Abujamous
Interpreting BRCA1 variants of uncertain significance (VUS) in underrepresented populations presents significant challenges due to the scarcity of ancestry-matched reference data, which can lead to an overestimation of variant rarity. This ...
SLC28A3 expression and fludarabine-emergent autoimmune hemolytic anemia in chronic lymphocytic leukemia: A new player in an old equation [0.03%]
尿苷转运蛋白SLC28A3在慢性淋巴细胞白血病患者中与氟达拉滨相关自身免疫性溶血贫血的关系研究：旧等式中的新角色
Vojin Vukovic,Teodora Karan-Djurasevic,Darko Antic et al.
Vojin Vukovic et al.
Fludarabine treatment in patients with chronic lymphocytic leukemia (CLL) has been associated with immune dysregulation and the development of autoimmune hemolytic anemia (AIHA). Prior research indicates a potential correlation between the ...