Postoperative multimodal pain management: a narrative review of current practices, clinical and educational gaps, and future directions [0.03%]
术后多模式镇痛：当前实践、临床及教育差距和未来方向的叙事综述
Braden M Lopez,Brent M Lee,Michael D Miller et al.
Braden M Lopez et al.
Pain is among the most commonly reported side effects following surgical interventions; however, its management remains a significant challenge due to its multifaceted nature, with studies indicating that up to 80% of surgical patients expe...
The role of the rectus sheath block in modern perioperative care for midline laparotomy: a review of the evidence [0.03%]
腹正中切口手术现代围术期Rectus Sheath Block作用的证据回顾
Marcus Abbawy,David Okoh,Arundhati Binuraj et al.
Marcus Abbawy et al.
Perioperative management of pain is crucial in optimising patient outcomes after laparotomy. This review focuses on the rectus sheath block (RSB) and its use in midline laparotomies. This article will examine the current evidence on the cli...
Towards a precision approach to anesthetic/analgesic immunomodulation in cancer [0.03%]
向癌症麻醉/镇痛免疫调节的精准方法迈进
Hersh V Gupta,Kay S Tan,Gregory W Fischer et al.
Hersh V Gupta et al.
Background: Immunomodulation is widely invoked to explain possible effects of anesthetic/analgesic drugs on recurrence and survival in cancer patients. By analogy with immune checkpoint inhibitors, which enhance anti-tumo...
Long-term sensorimotor changes after a sciatic nerve block with bupivacaine and liposomal bupivacaine in a high-fat diet/low-dose streptozotocin rodent model of diabetes [0.03%]
布比卡因和脂质体布比卡因坐骨神经阻滞后，在高脂肪饮食/低剂量链脲佐菌素糖尿病啮齿动物模型中的长期感觉运动改变
Susanna C Byram,Krista M Lotesto,Michael Volyanyuk et al.
Susanna C Byram et al.
Introduction: It is unclear whether patients with diabetes are more susceptible to nerve toxicity of local anesthetics or whether nerve blocks can accelerate the progression of diabetic peripheral neuropathy. Bupivacaine ...
Early incident and subsyndromal delirium in older patients undergoing elective surgical procedures: a randomized clinical trial of an avoid delirium protocol [0.03%]
老年患者选择性手术早期发生病状与轻度迷乱精神症：一项随机临床试验（避免迷乱方案）
Alisha Sachdev,Yabtsega Moges,Micah Rubin et al.
Alisha Sachdev et al.
Background: Pharmacological avoidance guidelines for preventing delirium have been suggested; however, there are limited pragmatic studies of these strategies. Early (65 years) patients undergoing elective surgeries. ...