Statistical optimization of glucose, sodium citrate and potassium chloride supplementation for enhanced bacteriocin production by Lactococcus lactis MT186647 and Lactobacillus fermentum MT186598 isolated from fermenting Pentaclethra macrophylla benth [0.03%]
来自Pentaclethra macrophylla benth发酵的Lactococcus lactis MT186647和Lactobacillus fermentum MT186598产生抗菌素的统计优化补充葡萄糖、柠檬酸钠和氯化钾的方法
Chijioke Ethel Onwuakor,Anayochukwu Chibuike Ngene
Chijioke Ethel Onwuakor
Bacteriocin production by lactic acid bacteria (LAB) is strongly conditioned by growth-medium composition, and adjusting ingredients offers a low-cost route to enhanced yield. Response surface methodology (RSM) based on a three-factor, five...
Evaluation of Fourier transform infrared spectroscopy as a first-line surveillance typing tool for Serratia spp. isolates derived from clinical materials [0.03%]
傅里叶变换红外光谱作为临床分离培养物serratia菌种的第一线监测分型工具的效果评估研究
Tristan Lüdecke,Klaus-Peter Hunfeld
Tristan Lüdecke
Introduction: Fourier transform infrared spectroscopy (FTIR) has been evaluated as a typing method for a number of pathogens; however, very little research has been conducted on the genus Serratia. ...
Linezolid MIC creep among clinically significant S. aureus: a retrospective eight-year study [0.03%]
利奈唑胺MIC值漂移的临床分离株凝固酶阳性葡萄球菌的8年回顾性研究
Chinchana Shylaja Eshwarappa,Veerabhadra Swamy Gs,Supreetha R Shettar et al.
Chinchana Shylaja Eshwarappa et al.
Introduction: The rising threat of antimicrobial resistance, particularly the phenomenon of MIC creep, poses a significant challenge to the clinical effectiveness of key antibiotics. Linezolid is a crucial last-resort age...
Editorial: Accelerating antibiotic development from natural products: tackling antimicrobial resistance (AMR) [0.03%]
editorial：加速抗生素开发应对微生物抗药性（amr）问题
Sanjib Bhakta,Cynthia Amaning Danquah,RuAngelie Edrada-Ebel et al.
Sanjib Bhakta et al.
Accelerating antibiotic development from natural products. Natural products with antimicrobial activity can act through multiple mechanisms to overcome antibiotic resistance. These include directly inhibiting bacterial growth, reversing res...
Editorial: Natural products and microbial interactions: from antimicrobial activity to microbial modulation [0.03%]
编者按：天然产物与微生物互作：从抗菌活性到菌群调控
Pablo Mendez-Pfeiffer,Manuel G Ballesteros-Monrreal,Mayra Mendez-Encinas et al.
Pablo Mendez-Pfeiffer et al.
Coagulation dysfunction events associated with novel tetracycline-class drugs: a disproportionality and Bayesian analysis based on the FAERS database [0.03%]
新的四环素类药物相关凝血功能障碍事件：来自FAERS数据库的 disproportionality和Bayesian分析
Hongxin Li,Jun Wang,Lingjun Kong et al.
Hongxin Li et al.
Introduction: In contemporary clinical practice, novel tetracycline-class antimicrobial agents have been increasingly utilized due to their favorable pharmacological profiles. However, the potential association between no...
Impact of a structured urine culture request form on antimicrobial stewardship in urinary tract infections at a tertiary care hospital in India [0.03%]
结构化尿培养申请单在印度三级医院泌尿系统感染抗菌管理中的影响研究
Supreeta R Shettar,Mahadevaiah Neelambike Sumana,Manjunath S Shetty et al.
Supreeta R Shettar et al.
Background: Interpretation of urine culture results requires key clinical information such as symptom status, catheterization, and multidrug-resistant organism (MDRO) risk. However, this information is frequently absent f...
Empirical antibiotic prescribing in COVID-19 patients: patterns and predictors in a resource-constrained Central Indian setting [0.03%]
COVID-19患者的经验性抗生素处方：资源匮乏的印度中部地区的模式和预测因素
Manju Purohit,Deepali Pathak,Devendra Baghel et al.
Manju Purohit et al.
Background: Empirical antibiotic prescribing during the COVID-19 pandemic may have accelerated antimicrobial resistance, particularly in resource-constrained settings with limited diagnostic and stewardship capacity. This...
Antimycobacterial peptides as natural therapeutics for tuberculosis: mechanisms and structural features [0.03%]
抗分枝杆菌多肽作为治疗结核病的天然药物：机制和结构特征
Pulak Pritam,Sreelipta Das,Sandeep Kumar Behera et al.
Pulak Pritam et al.
The disease tuberculosis, caused by Mycobacterium tuberculosis, is one of the leading causes of global human mortality. The rise of multidrug and extensively drug-resistant strains of the pathogen and the limited efficacy of the BCG vaccine...
Microbial interactions of EDTA: recent advances and biological applications in the context of natural product modulation [0.03%]
乙二胺四乙酸（EDTA）的微生物互作：天然产物调控背景下的新进展与生物应用
Gunanidhi Sahoo,Aditi Jena,Sudipta Kumar Patra et al.
Gunanidhi Sahoo et al.
Background and objectives: Ethylenediaminetetraacetic acid (EDTA) and its salts have been the choice of chelating agents since the 1940s. This review presents an updated details of their synthesis, general biology, ecotox...