The effect of African ancestry and mismatch-repair enzyme deficiency/microsatellite instability-high on colorectal adenocarcinoma immune gene expression [0.03%]
非洲血统和错配修复酶缺乏/微卫星不稳定高对结直肠腺癌免疫基因表达的影响
Dimitri F Joseph,Andrew Fu,Ricardo E Flores et al.
Dimitri F Joseph et al.
Background: Previous analyses of bulk colon and rectal adenocarcinoma (COAD/READ) RNA-sequence data comparing African ancestry (AA) and European ancestry (EA) groups have reported differentially expressed genes related to...
Sean T Koester,Naisi Li,Neelendu Dey
Sean T Koester
Ret is implicated in colorectal cancer (CRC) as both a proto-oncogene and a tumor suppressor. We asked whether RET signaling regulates tumorigenesis in an Apc-deficient preclinical model of CRC. We observed a sex-biased phenotype: Apc Min/+...
Spring-mediated distraction enterogenesis may alter the course of adaptation in porcine short bowel syndrome [0.03%]
弹簧介导的牵张肠生成可能改变猪短肠综合征适应过程的发展方向
Geoanna M Bautista,Genia Dubrovsky,Nicolle K Sweeney et al.
Geoanna M Bautista et al.
Introduction: Severe forms of short bowel syndrome (SBS) resulting in chronic intestinal failure (IF) have limited therapeutic options, all of which are associated with significant morbidities. Spring-mediated distraction...
Addressing the unmet clinical need for low-volume assays in early diagnosis of pancreatic cancer [0.03%]
针对胰腺癌早期诊断低样本量检测的临床需求探索
Daniel A Sheik,Kaleb Byers,Mini Thomas et al.
Daniel A Sheik et al.
The incidental detection of pancreatic cysts, an opportunity for the early detection of pancreatic cancer, is increasing, owing to an aging population and improvements in imaging technology. The classification of pancreatic cystic precursor...
Plasma, urine, and stool metabolites in response to dietary rice bran and navy bean supplementation in adults at high-risk for colorectal cancer [0.03%]
膳食米糠和黑豆补充对高结直肠癌风险成人尿液、粪便及血浆代谢物的影响
Emily B Hill,Bridget A Baxter,Brigitte Pfluger et al.
Emily B Hill et al.
Introduction: Dietary intake of whole grains and legumes and adequate physical activity (PA) have been associated with reduced colorectal cancer (CRC) risk. A single-blinded, two-arm, randomized, placebo-controlled pilot ...
Primary sclerosing cholangitis and pancreatic cancer: A retrospective cohort study of United States veterans [0.03%]
原发性硬化性胆管炎和胰腺癌：美国退伍军人回顾性队列研究
Anita Nguyen,Babak Torabi Sagvand,Madeline Alizadeh et al.
Anita Nguyen et al.
Primary sclerosing cholangitis (PSC) is associated with hepatobiliary and colorectal cancers, but it remains uncertain if PSC increases the risk for pancreatic cancer. While some European studies have suggested an increased risk of pancreat...
Investigating the effects of long-term Aroclor 1260 exposure on fatty liver disease in a diet-induced obesity mouse model [0.03%]
长期阿罗克洛尔1260暴露对饮食诱导的肥胖小鼠脂肪肝的影响研究
Kimberly Z Head,Oluwanifemi E Bolatimi,Tyler C Gripshover et al.
Kimberly Z Head et al.
Introduction: Polychlorinated biphenyls (PCBs) are persistent environmental toxicants that have been implicated in numerous health disorders including liver diseases such as non-alcoholic fatty liver disease (NAFLD). Toxi...
Sex-specific association between alcohol consumption and liver cirrhosis: An updated systematic review and meta-analysis [0.03%]
酒精消耗和肝硬化之间的性别特异性关联：一项系统综述和meta分析更新
Laura Llamosas-Falcón,Charlotte Probst,Charlotte Buckley et al.
Laura Llamosas-Falcón et al.
Different studies have shown that females develop liver diseases at lower levels of alcohol consumption than males. Our aim was to quantify the dose-response relationship between alcohol consumption and the risk of liver cirrhosis by sex an...