The association of ACE I/D polymorphism with the severity of COVID-19 in Iranian patients: A case-control study [0.03%]
ACE I/D多态性与伊朗COVID-19患者病情严重程度的相关性:一项病例对照研究
Javad Soltani Rezaiezadeh,Javad Safdari Lord,Mir Saeed Yekaninejad et al.
Javad Soltani Rezaiezadeh et al.
Background: Since the beginning of the COVID-19 pandemic, researchers have tried to find the reason behind the variety of the symptoms and disease severity among patients. It seems that genetic background may contribute i...
Role of circulatory miRNA-21 and associated signaling pathways in the pathogenesis of pulmonary fibrosis among individuals recovered after COVID-19 infection [0.03%]
新冠病毒感染后恢复期个体中循环miRNA-21及其相关信号通路在肺纤维化发病机制中的作用
Mohammad Ali,Fahed Abdullah,Aleemuddin Naveed et al.
Mohammad Ali et al.
Introduction: Currently pulmonary fibrosis in post-COVID individuals represents a crucial milieu of investigation due to long-term associated complications and worse clinical outcome. Lack of studies in Indian population ...
Differential gene expression of SARS-CoV-2 transcriptome provides insight into the design of more sensitive diagnostic tests [0.03%]
SARS-CoV-2转录组的差异基因表达为更敏感诊断试验的设计提供了思路
Mohadeseh Ahmadi,Reza Alizadeh-Navaei,Mohammadreza Haghshenas et al.
Mohadeseh Ahmadi et al.
The Coronavirus disease 2019 (COVID-19) pandemic is being addressed through RT-PCR, a frontline diagnostic technique. We evaluated gene expression patterns to improve the accuracy and sensitivity of current diagnostic tests. We downloaded r...
Association of Toll-like receptor-4 polymorphism with SARS CoV-2 infection in Kurdish Population [0.03%]
toll-like受体-4多态性与柯尔克孜族人群Sars Cov-2感染的关系
Hussein N Ali,Sherko S Niranji,Sirwan M A Al-Jaf
Hussein N Ali
Genetic variations are critical for understanding clinical outcomes of infections including server acute respiratory syndrome coronavirus 2 (SARS CoV-2). The immunological reactions of human immune genes with SARS CoV-2 have been under inve...
Comparison between the accuracy of chest computerized tomography vs. reverse transcriptase polymerase chain reaction in a tertiary care center in Lebanon; along with their correlation to mortality, morbidity and symptoms in COVID-19 patients [0.03%]
黎巴嫩一家三级护理中心的胸部计算机断层扫描与逆转录聚合酶链反应在COVID-19患者中的准确性比较及其与死亡率、发病率和症状的关系
Noor Hanania,Elie Najem,Hani Tamim et al.
Noor Hanania et al.
Objectives: Chest Computerized Tomography has been widely used in COVID patients' assessment. Hence the question arises as to whether there is any correlation between the Ct value and findings on Chest CT scan or clinical...
In silico transcriptional analysis of asymptomatic and severe COVID-19 patients reveals the susceptibility of severe patients to other comorbidities and non-viral pathological conditions [0.03%]
无症状和重症COVID-19患者的转录组分析表明,重症患者易并发其他疾病和非病毒病理状态
Poonam Sen,Harpreet Kaur
Poonam Sen
COVID-19 is a severe respiratory disease caused by SARS-CoV-2, a novel human coronavirus. Patients infected with SARS-CoV-2 exhibit heterogeneous symptoms that pose pragmatic hurdles for implementing appropriate therapy and management of th...
In silico identification of potential miRNAs -mRNA inflammatory networks implicated in the pathogenesis of COVID-19 [0.03%]
基于计算的COVID-19潜在miRNA-mRNA炎性网络识别
Somayeh Hashemi Sheikhshabani,Zeinab Amini-Farsani,Parastoo Modarres et al.
Somayeh Hashemi Sheikhshabani et al.
COVID-19 has been found to affect the expression profile of several mRNAs and miRNAs, leading to dysregulation of a number of signaling pathways, particularly those related to inflammatory responses. In the current study, a systematic biolo...
Gene expression pattern in severely progressing covid-19 patients is related to diabetes mellitus type 1: A functional annotation analysis [0.03%]
基因表达模式与1型糖尿病密切相关:严重进展的COVID-19患者的功能注释分析
Mohsen Alipour,Danesh Javeshghani,Abazar Roustazadeh
Mohsen Alipour
Aims: The aim of this study was to extract the signaling mediators or biological pathways that link covid-19 to other diseases such as type 1 diabetes mellitus (T1DM). ...
The impacts of 13 novel mutations of SARS-CoV-2 on protein dynamics: In silico analysis from Turkey [0.03%]
来自土耳其的SARS-CoV-2 13种新型突变体对蛋白质动力学影响的仿真分析
Sezin Unlu,Aylin Uskudar-Guclu,Isli Cela
Sezin Unlu
SARS-CoV-2 inherits a high rate of mutations making it better suited to the host since its fundamental role in evolution is to provide diversity into the genome. This research aims to identify variations in Turkish isolates and predict thei...
Potential impact of serpin peptidase inhibitor clade (A) member 4 SERPINA4 (rs2093266) and SERPINA5 (rs1955656) genetic variants on COVID-19 induced acute kidney injury [0.03%]
SERPINA4(rs2093266)和SERPINA5(rs1955656)基因变异对新型冠状病毒肺炎诱导的急性肾损伤的潜在影响
Sally M El-Hefnawy,Zeinab A Kasemy,Hanaa A Eid et al.
Sally M El-Hefnawy et al.
Background: SARS-CoV-2 has a number of targets, including the kidneys. Acute Kidney Injury (AKI) might develop in up to a quarter of SARS-CoV-2 patients. In the clinical environment, AKI is linked to a high rate of death ...