The mechano-electric feedback mediates the dual effect of stretch in mouse sinoatrial tissue [0.03%]
机械电反馈介导了小鼠心房窦组织牵张的双重作用
Limor Arbel Ganon,Rami Eid,Matan Hamra et al.
Limor Arbel Ganon et al.
The sinoatrial node (SAN) is the primary heart pacemaker. The automaticity of SAN pacemaker cells is regulated by an integrated coupled-clock system. The beat interval (BI) of SAN, and its primary initiation location (inferior vs. superior)...
Sex-specific effects of in vitro culture and embryo transfer on cardiac growth in sheep offspring [0.03%]
体外培养和胚胎移植对绵羊后代心脏生长的性别特异性影响
Monalisa Padhee,Mitchell C Lock,I Caroline McMillen et al.
Monalisa Padhee et al.
Embryo culture with and without human serum supplementation, previously common practice in assisted reproductive technologies (ARTs), have been associated with increased heart weight in early and late gestation in the sheep fetus. The prese...
Omecamtiv mecarbil in precision-cut living heart failure slices: A story of a double-edged sword [0.03%]
奥马西韦麦克达比尔在精密切割的活体心力衰竭切片中的研究：一把双刃剑的故事
Jorik H Amesz,Sanne J J Langmuur,Mark F A Bierhuizen et al.
Jorik H Amesz et al.
Heart failure (HF) is a rapidly growing pandemic while medical treatment options remain limited. Omecamtiv mecarbil (OM) is a novel HF drug that directly targets the myosin heads of the cardiac muscle. This study used living myocardial slic...
Unveiling the neural remodelling landscape in heart failure: A new frontier in cardiac arrhythmogenesis research [0.03%]
揭开心力衰竭中神经重塑的景观：心脏电重构研究的新前沿
Alexander Grassam-Rowe,Ming Lei
Alexander Grassam-Rowe
Circulating levels of cadherins are associated with atherosclerosis and cardiovascular outcomes [0.03%]
血浆闭合蛋白与动脉粥样硬化和心血管结局的关系
Gaetano Santulli,Fahimeh Varzideh,Yifei Qin et al.
Gaetano Santulli et al.
Female cardioprotection in ischemia/reperfusion: Isn't a SUR thing anymore? [0.03%]
缺血/再灌注条件下女性心脏保护：不再仅仅是SUR的问题了？
Annalara G Fischer,Helen E Collins
Annalara G Fischer
Rada Ellegård,Torsten Malm,Constance G Weismann et al.
Rada Ellegård et al.
Background: Coarctation of the aorta (CoA) is a relatively common congenital heart defect. The underlying causes are not known, but a combination of genetic factors and abnormalities linked to embryonic development is sus...
Increased perivascular fibrosis and pro-fibrotic cellular transition in intramyocardial blood vessels in myocardial infarction patients [0.03%]
心肌梗塞患者心肌内血管周围纤维化增加及促纤维化的细胞转化增强
Zhu Jiang,Giulia Sorrentino,Suat Simsek et al.
Zhu Jiang et al.
Background and objectives: Structural and functional changes in the intramyocardial microcirculation increase the risk of myocardial infarction (MI). This study investigated intramyocardial perivascular fibrosis and pro-f...
Elise S Bisset,Susan E Howlett
Elise S Bisset
Applying adipose tissue-derived stem cell therapies as a novel treatment for atherosclerotic plaque development: Importance of appropriate dosing [0.03%]
应用脂肪组织来源干细胞疗法治疗动脉粥样硬化斑块发展：适当剂量的重要性
Michael F Allen,Song-Young Park
Michael F Allen