Endothelial identity not found - Beyond passage 38, commercial cardiac microvascular endothelial cells do not express CD31 and VE-cadherin [0.03%]
内皮细胞身份丢失：传代超过38代后商业来源的心脏微血管内皮细胞不再表达CD31和VE-钙粘蛋白
Sarah Hilderink,Jolanda van der Velden,Diederik W D Kuster
Sarah Hilderink
Few immortalized cardiac microvascular endothelial cell (CMEC) lines are available, particularly mouse lines. We purchased the CLU510 mCMEC line (Cedarlane), isolated by fluorescence-activated cell sorting for CD31 and VE-cadherin. The cell...
The cardiac blood transcriptome predicts de novo onset of atrial fibrillation in heart failure [0.03%]
心力衰竭患者心脏血液转录组预测房颤的新发发生
Guillaume Lamirault,Imen Fellah-Hebia,Catherine Chevalier et al.
Guillaume Lamirault et al.
Heart failure (HF) increases the risk of developing atrial fibrillation (AF), leading to increased morbidity and mortality. Therefore, better prediction of this risk may improve treatment strategies. Although several predictors based on cli...
Transcriptomic research in atherosclerosis: Unravelling plaque phenotype and overcoming methodological challenges [0.03%]
转录组学在动脉粥样硬化研究中的应用：揭示斑块表型和克服方法学挑战
Miron Sopić,Kanita Karaduzovic-Hadziabdic,Dimitris Kardassis et al.
Miron Sopić et al.
Atherosclerotic disease is a major cause of acute cardiovascular events. A deeper understanding of its underlying mechanisms will allow advancing personalized and patient-centered healthcare. Transcriptomic research has proven to be a power...
Genetics-diet crossroads: Unveiling new insights into hypertrophic cardiomyopathy [0.03%]
遗传与饮食的交汇点：肥厚型心肌病的新见解
Steffen P Häseli,Gabriele G Schiattarella
Steffen P Häseli
Endothelin-based markers for endothelial dysfunction in chemotherapy-induced cardiotoxicity [0.03%]
化疗所致心毒性内皮功能障碍的内皮素标志物
Gabrielle Boutin,Jale Yuzugulen,Md Zahidul Islam Pranjol
Gabrielle Boutin
Current cardiac biomarkers, troponins and brain natriuretic peptide, are primarily used to assist in the diagnosis or exclusion of myocardial damage and congestive heart failure, respectively. The use of these biomarkers in chemotherapy-ind...
Western diet triggers cardiac dysfunction in heterozygous Mybpc3-targeted knock-in mice: A two-hit model of hypertrophic cardiomyopathy [0.03%]
西方饮食可诱发Mybpc3位点杂合突变小鼠心脏功能障碍：肥厚性心肌病的双重打击模型
Edgar E Nollet,Sila Algül,Max Goebel et al.
Edgar E Nollet et al.
Background and aim: Phenotypic expression of hypertrophic cardiomyopathy (HCM) and disease course are associated with unfavorable metabolic health. We investigated if Western diet (WD) feeding is sufficient to trigger car...
Starting off strong: Rigor and reproducibility in the early career [0.03%]
严守科研规范，确保研究可重复性——致初入职场的科学家们
Ronald J Vagnozzi
Ronald J Vagnozzi
The effect of moderate intensity aerobic exercise on cardiovascular function, cardiorespiratory fitness and estrogen receptor alpha gene in overweight/obese postmenopausal women: A randomized controlled trial [0.03%]
中等强度有氧运动对超重和肥胖绝经后女性心血管功能、心肺健康及雌激素受体α基因的影响：一项随机对照试验
Abbas Malandish,Mohammad Rahmati-Yamchi
Abbas Malandish
Objective: The purpose of this study was to examine the effect of 12 weeks of moderate intensity aerobic exercise on echocardiographic and cardiorespiratory fitness (CRF) parameters, lymphocyte estrogen receptor alpha (ER...
Dominic P Del Re,Qinghang Liu
Dominic P Del Re