Increased percentage of HLA-DR T cells in untreated juvenile dermatomyositis [0.03%]
未经治疗的青少年皮肌炎中HLA-DR T细胞比例升高
Amer Khojah,Madeline Schutt,Gabrielle Morgan et al.
Amer Khojah et al.
This study investigates HLA-DR expression on activated T cells and serum neopterin levels in Juvenile Dermatomyositis (JDM) children pre- and post-treatment. Sixty-nine JDM children (less than 18 years) were included. Elevated HLA-DR+ T cel...
Altered pre-existing SARS-CoV-2-specific T cell responses in elderly individuals [0.03%]
老年人的SARS-CoV-2特异性T细胞反应改变
Naoyuki Taira,Sakura Toguchi,Mio Miyagi et al.
Naoyuki Taira et al.
Pre-existing SARS-CoV-2-specific T cells, but not antibodies, have been detected in some unexposed individuals. This may account for some of the diversity in clinical outcomes ranging from asymptomatic infection to severe COVID-19. Although...
Prevalence of asymptomatic SARS-CoV-2 infection in an Austrian cohort [0.03%]
奥地利队列中无症状SARS-CoV-2感染的流行率
Elisabeth Mara,Verena Breitsching,Tanja Schuster et al.
Elisabeth Mara et al.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) first emerged at the end of 2019, causing the coronavirus disease (COVID-19). The main sources of infections are infected and asymptomatic persons. One major problem of the pandem...
Pharmacokinetics of convalescent plasma therapy in a COVID-19 patient with X-linked Agammaglobulinemia [0.03%]
X连锁低丙种球蛋白血症COVID-19患者恢复期血浆治疗的药代动力学特征分析
Jennifer L Yates,David S Palat,M Kristina Subik et al.
Jennifer L Yates et al.
Convalescent plasma (CP) has been the first line of defense against numerous infectious diseases throughout history. The COVID-19 pandemic created a need for a quick, easily accessible, and effective treatment for severe disease and CP was ...
COVID-19 in a patient with Good's syndrome and in 13 patients with common variable immunodeficiency [0.03%]
戈德综合征和13例常见变量免疫缺陷患者的COVID-19感染
Hannes Lindahl,C I Edvard Smith,Peter Bergman
Hannes Lindahl
Antibody deficiencies constitute the majority of primary immunodeficiencies in adults. These patients have a well-established increased risk of bacterial infections but there is a lack of knowledge regarding the relative risks upon contract...
Alexandre Landry,Stéphanie Crapoulet,Luc H Boudreau et al.
Alexandre Landry et al.
We present a rare case of meningoradiculitis occurring after mRNA COVID-19 vaccination. This patient, with a history of inflammatory arthritis following rubella vaccination, presented to the emergency department 4 days after her vaccination...
The "original antigenic sin" and its relevance for SARS-CoV-2 (COVID-19) vaccination [0.03%]
“原抗原则”及其对SARS-CoV-2（COVID-19）疫苗接种的相关性
Ger T Rijkers,Frans J van Overveld
Ger T Rijkers
Imprinting of the specific molecular image of a given protein antigen into immunological memory is one of the hallmarks of immunity. A later contact with a related, but different antigen should not trigger the memory response (because the p...
Guillain-Barre syndrome: An autoimmune disorder post-COVID-19 vaccination? [0.03%]
新冠疫苗接种后的吉兰-巴雷综合征：一种自身免疫性疾病？
Zafran Khan,Ubaid Ahmad,Daniya Ualiyeva et al.
Zafran Khan et al.
SARS-CoV-2 causes Coronavirus Disease 2019 (COVID-19), an infectious condition that can present none or one or more of these symptoms: fever, cough, headache, sore throat, loss of taste and smell, aches, fatigue and musculoskeletal pain. Fo...
Appraising SARS-CoV-2 infections after full mRNA COVID-19 vaccination in patients with systemic lupus erythematosus (SLE) [0.03%]
系统性红斑狼疮患者接种新冠mRNA疫苗后感染SARS-CoV-2的评估
Anderson Anuforo,Michael Sandhu,Jianghong Yu et al.
Anderson Anuforo et al.
The 2019 Coronavirus disease (COVID-19) vaccine is a major weapon in the fight against the severe acute respiratory syndrome brought about by coronavirus 2 (SARS-CoV-2). The vaccine significantly reduces the risk and severity of infection b...
Pfizer-biontech COVID-19 RNA vaccination induces phosphatidylserine autoantibodies, cryoglobulinemia, and digital necrosis in a patient with pre-existing autoimmunity [0.03%]
一项关于辉瑞-BioNTech新冠RNA疫苗的研究：自身免疫病患者接种后出现抗磷脂抗体、冷球蛋白血症和肢体末端坏死
Sandy Nasr,Sara Khalil,Bernard J Poiesz et al.
Sandy Nasr et al.
We describe a 64-year-old Caucasian female with a history of Raynaud's disease, hand arthritis, photosensitivity, Sjogren's syndrome and leukocytoclastic vasculitis who presented with progressively worsening fingertip necrosis that began th...