PICCs versus PORTs, an Australian perspective. Comment on BJA Open 2025; 13: 100377 [0.03%]
关于BJA Open 2025; 13: 100377的评论：从澳大利亚角度看，PICC优于PORT
Stuart Walker,Louise Nott
Stuart Walker
Patient preference for intraoperative opioid use and early recovery after noncardiac surgery: protocol for a randomised factorial design trial of opioid-free versus opioid-based anaesthesia (the PERFECT trial) [0.03%]
患者偏好的术中阿片类药物使用及其对非心脏手术后早期恢复的影响：无阿片类麻醉与基于阿片类的麻醉对照试验（PERFECT试验）方案
Yann Gricourt,Nancy M Boulos,Amelie Delaporte et al.
Yann Gricourt et al.
Introduction: Although opioids are commonly used to relieve pain associated with surgery, they are not consequence free. Moreover, the USA and many western countries are currently experiencing a significant health crisis ...
Clinical Trial
BJA open. 2025 Jun 18:15:100420. DOI:10.1016/j.bjao.2025.100420 2025
Anxiety and induction of anaesthesia in children: the impact of big data and children's rights [0.03%]
大数据和儿童权利对儿童麻醉诱导的影响及焦虑感
Tom Giedsing Hansen,Susan M Goobie,Thomas Engelhardt
Tom Giedsing Hansen
This editorial explores the role of big data in understanding paediatric anaesthesia anxiety, analysing a study of 155 000 cases. It highlights challenges such as parental presence, premedication, and methodological limitations. The authors...
Systemic role of orexin A, substance P, bradykinin, and DABK in severe COVID-19 and 2.5-yr follow-ups: an observational study [0.03%]
促黑激素受体激动肽、食欲素A、缓激肽和DABK在重度COVID-19中的系统性作用及2.5年随访：观察性研究
Ulrike Heinicke,Steven R Talbot,Filippos Thanasis et al.
Ulrike Heinicke et al.
Background: Orexin A regulates sleep-wake cycles, arousal, and energy homeostasis, linking it to the renin-angiotensin system and substance P. Dysfunction in these pathways occurs in acute and long-term COVID-19, includin...
Long-term outcomes of time-dependent phenotypes of perioperative myocardial injury☆ [0.03%]
围手术期心肌损伤时变表型的长期结局
Mikael Fält,Rasmus Åhman,Fredrik Hammarskjöld et al.
Mikael Fält et al.
Background: Perioperative myocardial injury (PMI) is associated with increased short-term major adverse cardio- and cerebrovascular events (MACCE) and mortality. We evaluated how different phenotypes of PMI based on timin...
Investigating the effectiveness of an intraoperative decision support guided fluid therapy intervention on postoperative outcome of high-risk patients undergoing high-risk abdominal surgery: protocol for an international multicentre stepped-wedge cluster-randomised implementation trial [0.03%]
术中决策支持指导的液体治疗干预对高风险患者腹部手术后结果的影响：国际多中心分阶段集群随机实施试验方案
Sean Coeckelenbergh,Amelie Delaporte,Damien Rousseleau et al.
Sean Coeckelenbergh et al.
Background: Inappropriate fluid administration can impact patient outcome. Intraoperative advanced haemodynamic monitoring coupled with a treatment protocol based on stroke volume optimisation can help determine the appro...
Clinical Trial
BJA open. 2025 Jun 5:14:100421. DOI:10.1016/j.bjao.2025.100421 2025
A GAP analysis of the current state of Pain Management Services in the UK, 2024 [0.03%]
2024年英国疼痛管理服务现状的差距分析（GAP分析）
Sue Copley,Beatrice Bretherton,Suzanne Carty et al.
Sue Copley et al.
Background: In the UK, multidisciplinary services for patients experiencing chronic pain are currently commissioned by the NHS as specialised services. Pain services across the UK were placed under significant strain duri...
Glucose variability and mode of anaesthesia in major noncardiac surgery (GlucoVITAL): study protocol for a randomised controlled trial [0.03%]
glucose variability和麻醉方式在重大非心脏手术中的作用（GlucoVITAL）：随机对照试验研究方案
Henrike Janssen,Priyanthi Dias,Louise Hiller et al.
Henrike Janssen et al.
Background: Hyperglycaemia after noncardiac surgery occurs commonly and is associated with complications. The choice of maintenance anaesthesia may promote hyperglycaemia and increase glucose variability, both of which ex...
Clinical Trial
BJA open. 2025 May 24:14:100419. DOI:10.1016/j.bjao.2025.100419 2025
Intraoperative methadone for postoperative pain in adult patients undergoing tonsillectomy-a randomised controlled trial [0.03%]
成人扁桃体切除术患者术中使用吗啡类止痛药甲太东治疗术后疼痛的随机对照试验
Michael Bøndergaard,Peter Gaarsdal Uhrbrand,Tutku Karaca et al.
Michael Bøndergaard et al.
Background: Tonsillectomy is a common procedure often associated with severe postoperative pain. This study hypothesised that methadone would provide superior postoperative pain relief and reduced opioid consumption compa...
Derivation and internal-external validation of clinical prediction model for postoperative clinically important hypotension in patients undergoing noncardiac surgery: an international prospective cohort study [0.03%]
非心脏手术后患者术后重要低血压的临床预测模型的派生及内部和外部验证：一项国际前瞻性队列研究
Stephen Su Yang,German Malaga,Maria Lazo-Porras et al.
Stephen Su Yang et al.
Background: Intraoperative and postoperative hypotension are associated with myocardial injury/infarction, stroke, acute kidney injury, and death. Because of its prolonged duration, postoperative hypotension contributes m...