Neoadjuvant immunotherapy for non-small cell lung cancer: Opportunities and challenges [0.03%]
非小细胞肺癌新辅助免疫治疗：机遇与挑战
Junjie Hu,Jing Zhang,Shiyue Wan et al.
Junjie Hu et al.
Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape for resectable non-small cell lung cancer. Numerous trials have explored the use of ICIs, either as monotherapy or in combination with other therapies, in the neoa...
Parkin deficiency aggravates inflammation-induced acute lung injury by promoting necroptosis in alveolar type II cells [0.03%]
Parkin缺乏通过促进肺泡II型细胞坏死性凋亡加重炎症诱导的急性肺损伤
Meiyu Quan,Qiang Guo,Xihua Yan et al.
Meiyu Quan et al.
Background: Necroptosis is a form of programmed cell death resulting in tissue inflammation due to the release of intracellular contents. Its role and regulatory mechanism in the context of acute lung injury (ALI) are unc...
Advances in the awareness of tuberculosis-associated chronic obstructive pulmonary disease [0.03%]
有关结核病相关慢性阻塞性肺疾病的认识进展
Xiaoyan Gai,Brian Allwood,Yongchang Sun
Xiaoyan Gai
Tuberculosis (TB) significantly increases the risk of developing chronic obstructive pulmonary disease (COPD), positioning TB-associated COPD (TB-COPD) as a distinct category within the spectrum of respiratory diseases prevalent, especially...
Lung-resident lymphocytes and their roles in respiratory infections and chronic respiratory diseases [0.03%]
肺驻留淋巴细胞及其在呼吸道感染和慢性呼吸系统疾病中的作用
Arka Sen Chaudhuri,Jie Sun
Arka Sen Chaudhuri
Recent scientific breakthroughs have blurred traditional boundaries between innate and adaptive immunity, revealing a sophisticated network of tissue-resident cells that deliver immediate, localized immune responses. These lymphocytes not o...
Burden of RSV among inpatients with lower respiratory tract infection under 5 years of age: A 10-year retrospective study in Southwest China from 2009 to 2019 [0.03%]
2009-2019年我国西南地区5岁以下儿童下呼吸道感染住院患者中RSV疾病负担：一项回顾性研究
Taoyu Li,Heping Fang,Xiangyu Liu et al.
Taoyu Li et al.
Objectives: Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infection (LRTI). However, few comprehensive descriptions of the disease burden, medical resource utilization (MRU), and costs of...
Overcoming EGFR-TKI resistance by targeting the tumor microenvironment [0.03%]
通过靶向肿瘤微环境来克服表皮生长因子受体酪氨酸激酶抑制剂的耐药性
Jinsong Zhang,Natalie Vokes,Man Li et al.
Jinsong Zhang et al.
Targeted therapy has ushered in a new era of precision medicine for non-small cell lung cancer (NSCLC). Currently, epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) stand as the recommended first-line therapy for adv...
Han Yang,Si Chen,Jiayuan Sun et al.
Han Yang et al.
Chronic inflammatory airway diseases, such as chronic bronchitis, chronic obstructive pulmonary disease, emphysema, and bronchial asthma, pose significant healthcare challenges. Interventional treatments offer promise as valuable complement...
Zhuxing Chen,Peng Liang,Haoxiang Xu et al.
Zhuxing Chen et al.
Patterns and trends in asthma incidence rates in main Asian and Western countries and their prediction to 2030 [0.03%]
主要亚洲和西方国家哮喘发病率的变化趋势及其至2030年的预测值
Yang Zheng,Lei Lan,Gan Lu et al.
Yang Zheng et al.
Background: The urbanization and industrialization of East and Southeast Asia in decades past has significantly altered living environment and lifestyles, which may have complicated effects on the burden of asthma. We aim...