Lactobacillus johnsonii CCFM1376 improves hypercholesterolemia in mice by regulating the composition of bile acids [0.03%]
鼠李糖乳杆菌CCFM1376通过调节胆汁酸的组成改善小鼠高胆固醇血症
Kexue Chen,Danting Dang,Huizhen Li et al.
Kexue Chen et al.
Aim: Strains with high bile salt hydrolase (BSH) activity have the potential to regulate cholesterol metabolism. This study aimed to assess the alleviating effect of Lactobacillus johnsonii (L. johnsonii) CCFM1376, a strain with high BSH ac...
A microbial symphony: a literature review of the factors that orchestrate the colonization dynamics of the human colonic microbiome during infancy and implications for future health [0.03%]
一首微生物的交响乐：关于影响婴儿期人类结肠菌群定植动态的因素及对未来健康的影响的文献综述
Edward Horwell,Philip Bearn,Simon M Cutting
Edward Horwell
Since the advent of new sequencing and bioinformatic technologies, our understanding of the human microbiome has expanded rapidly over recent years. Numerous studies have indicated causal links between alterations to the microbiome and a ra...
Potential applications of engineered bacteria in disease diagnosis and treatment [0.03%]
工程菌在疾病诊断和治疗中的潜在应用
Zhaowei Luo,Zhanghua Qi,Jie Luo et al.
Zhaowei Luo et al.
Probiotics are live microorganisms that confer health benefits to the host when administered in appropriate quantities. This beneficial effect has spurred extensive research in the medical and health fields. With rapid advancements in synth...
Host-microbiota interactions in the infant gut revealed by daily faecal sample time series [0.03%]
基于每日粪便样本的序列揭示婴儿肠道中宿主微生物群的相互作用
Nienke van Beek,Iiris Katavisto,Markku Lehto et al.
Nienke van Beek et al.
Aim: This study aims to explore the interplay between host immune factors and gut microbiota in human infants in vivo using time-series daily stool samples and identify biomarkers of host-microbe interactions. Methods: 216 faecal samples co...
Mobile genetic elements: the hidden puppet masters underlying infant gut microbiome assembly? [0.03%]
移动遗传元件：隐藏在婴儿肠道菌群组装背后的幕后操纵者吗？
Kim Kreuze,Ville-Petri Friman,Tommi Vatanen
Kim Kreuze
The gut microbiota is important for healthy infant development. Part of the initial colonizing microbial strains originate from the maternal gut, and undergo a selective event, termed the "colonization bottleneck". While vertical mother-to-...
Impact of mother's own milk vs. donor human milk on gut microbiota colonization in preterm infants: a systematic review [0.03%]
母乳与捐赠人乳对早产儿肠道菌群定植影响的系统评价
Jing Chen,Aranka J van Wesemael,Nerissa P Denswil et al.
Jing Chen et al.
Background: Nutritional intake in preterm infants is associated with short- and long-term outcomes. The favorable outcomes of preterm infants who predominantly receive their mother's own milk (MOM) are thought to be mediated partly through ...
Nolan K Newman,Philip M Monnier,Richard R Rodrigues et al.
Nolan K Newman et al.
Background: The gut microbiota has been implicated as a major factor contributing to metabolic diseases and the response to drugs used for the treatment of such diseases. In this study, we tested the effect of cholestyramine, a bile acid se...
The inner elbow skin microbiome contains Lactobacillus among its core taxa and varies with age, season and lifestyle [0.03%]
肘部内侧皮肤微生物组的核心类群含有乳酸菌且会随年龄、季节和生活方式而变化
Lize Delanghe,Ilke De Boeck,Joke Van Malderen et al.
Lize Delanghe et al.
Background: The human skin microbiome plays an essential role in protecting against pathogens and other external substances. This open ecosystem is also influenced by personal and environmental factors, but the precise impact of these facto...
Comparative genome analysis of microbial strains marketed for probiotic interventions: an extension of the Integrated Probiotic Database [0.03%]
益生菌干预营销的微生物菌株基因组比较分析：综合益生菌数据库的扩展
Silvia Petraro,Chiara Tarracchini,Gabriele Andrea Lugli et al.
Silvia Petraro et al.
Background: Members of the Bifidobacterium genus and lactobacilli are the most commonly used probiotics to promote human health. In this context, genome-based in silico analyses have been demonstrated as a fast and reliable tool for identif...
Secondary analysis reveals gut microbiota differences in patients with Parkinson's disease and/or cognitive impairment [0.03%]
二次分析揭示帕金森病患者和/或认知障碍患者的肠道微生物群差异
Xin Shen,Bing Leng,Shukun Zhang et al.
Xin Shen et al.
Background: Parkinson's disease (PD) is a neurodegenerative disorder, and the main clinical characteristics are bradykinesia and muscle stiffness. Cognitive impairment (CI) is a prevalent non-motor manifestation observed in individuals with...