Pathogen exclusion from intestinal mucus and antimicrobial susceptibility of Bifidobacterium spp. strains from fecal donors [0.03%]
肠道供体来源的两歧双歧杆菌菌株抗菌敏感性及病原菌排除作用研究
Aki Ronkainen,Imran Khan,Reetta Satokari
Aki Ronkainen
Aim: To study the ability of bifidobacterial strains isolated from fecal donors to prevent pathogens from adhering to intestinal mucus, along with their antimicrobial susceptibility. Methods: Pathogen prevention was assessed through an in v...
Host-dependent alteration of the gut microbiota: the role of luminal microRNAs [0.03%]
宿主依赖性的肠菌群变化：肠腔内microRNA的作用
Céline Cuinat,Jiali Pan,Elena M Comelli
Céline Cuinat
MicroRNAs (miRNAs) are short, non-coding RNAs that play gene expression regulatory roles in eukaryotes. MiRNAs are also released in body fluids, and in the intestine, they are found in the lumen and feces. Here, together with exogenous diet...
Advances in engineered bacteria vaccines for enhancing anti-cancer immunity [0.03%]
增强抗癌免疫的工程细菌疫苗研究进展
Wu Liu,Wenjing Chen,Yujie Cai et al.
Wu Liu et al.
Advances in synthetic biology have enabled the development of tumor-targeted live bacterial therapeutics. In a recent study published in Nature, Redenti et al. engineered Escherichia coli Nissle 1917(EcNcΔlon/ΔompT/LLO+ nAg), which exploi...
Regional microbial content of fermented traditional and industrial East Mediterranean sausages from the islands of Cyprus and Mytilini [0.03%]
塞浦路斯和米蒂林岛传统及工业东地中海香肠的地区性发酵微生物含量
Eleni Kamilari,Catherine Stanton,Dimitrios Tsaltas et al.
Eleni Kamilari et al.
Objective: To characterize the microbial biodiversity of fermented sausages from the East Mediterranean islands of Cyprus and Mytilini, and to identify differences between the microbial diversity of traditionally and industrially produced C...
Gerrit A Stuivenberg,Annabel Poon,Jeremy P Burton et al.
Gerrit A Stuivenberg et al.
The rising global incidence of atherosclerosis highlights the inadequacies in our understanding of the pathophysiology and treatment of the disease. Increasing evidence outlines the importance of the intestinal microbiome in atherosclerosis...
How human milk shapes the gut microbiota in preterm infants: potential for optimizing early-life microbial development [0.03%]
人类乳汁如何塑造早产儿肠道微生物群：优化生命早期微生物发育的潜力
Pamela Thomson,Daniel Garrido
Pamela Thomson
Breast milk plays a crucial role in shaping the gut microbiota of preterm infants, with significant microbial sharing influenced by feeding practices and antibiotics, highlighting the benefits of direct breastfeeding for gut health. ...
Munawar Abbas,Mark Tangney
Munawar Abbas
Microbial communities inhabiting various body sites play critical roles in the initiation, progression, and treatment of cancer. The gut microbiota, a highly diverse microbial ecosystem, interacts with immune cells to modulate inflammation ...
Profiling the gut and oral microbiota of hormone receptor-positive, HER2-negative metastatic breast cancer patients receiving pembrolizumab and eribulin [0.03%]
激素受体阳性、HER2阴性转移性乳腺癌患者接受帕博利尤单抗和埃洛尤单抗的肠道和口腔微生物组特征分析
Nancy My Teng,Andrea Malfettone,Matthew J Dalby et al.
Nancy My Teng et al.
Aim: Changes in host-associated microbial communities (i.e., the microbiota) may modulate responses to checkpoint blockade immunotherapy. In the KELLY phase II study (NCT03222856), we previously demonstrated that pembrolizumab [anti-program...
Compendium of Bifidobacterium-based probiotics: characteristics and therapeutic impact on human diseases [0.03%]
以乳双歧杆菌为代表的益生菌综述：特征及对人类疾病的治疗作用
Fabiana Bocchio,Leonardo Mancabelli,Christian Milani et al.
Fabiana Bocchio et al.
The human microbiota, a complex community of microorganisms residing in and on the human body, plays a crucial role in maintaining health and preventing disease. Bifidobacterium species have shown remarkable therapeutic potential across a r...
Galacto-oligosaccharides alone and combined with lactoferrin impact the Kenyan infant gut microbiota and epithelial barrier integrity during iron supplementation in vitro [0.03%]
低聚半乳糖及其与乳铁蛋白联合对肯尼亚婴儿肠道菌群和上皮屏障完整性的体外影响：一项体内铁补充研究
Carole Rachmühl,Christophe Lacroix,Adele Ferragamo et al.
Carole Rachmühl et al.
Aim: Iron supplementation to African weaning infants was associated with increased enteropathogen levels. While cohort studies demonstrated that specific prebiotics inhibit enteropathogens during iron supplementation, their mechanisms remai...