First encounters of the microbial kind: perinatal factors direct infant gut microbiome establishment [0.03%]
第一次相遇：围产期因素决定婴儿肠道菌群的建立
Kevin Linehan,Eugene M Dempsey,C Anthony Ryan et al.
Kevin Linehan et al.
The human gut microbiome harbors a diverse range of microbes that play a fundamental role in the health and well-being of their host. The early-life microbiome has a major influence on human development and long-term health. Perinatal facto...
Cross-feeding interactions between human gut commensals belonging to the Bacteroides and Bifidobacterium genera when grown on dietary glycans [0.03%]
肠道共生菌拟杆菌属和双歧杆菌属在定植于膳食多糖时的相互作用关系
Pedro Fernandez-Julia,Daniel M Commane,Douwe van Sinderen et al.
Pedro Fernandez-Julia et al.
Elements of the human gut microbiota metabolise many host- and diet-derived, non-digestible carbohydrates (NDCs). Intestinal fermentation of NDCs salvages energy and resources for the host and generates beneficial metabolites, such as short...
Cross-talk between the infant/maternal gut microbiota and the endocrine system: a promising topic of research [0.03%]
婴儿/母体肠道菌群与内分泌系统之间的交叉对话：一项富有前景的研究课题
Francesca Turroni,Sonia Mirjam Rizzo,Marco Ventura et al.
Francesca Turroni et al.
The infant gut microbiota is the set of microorganisms colonizing the baby's intestine. This complex ecosystem appears to be related to various physiological conditions of the host and it has also been shown to act as one of the most crucia...
A breath of fresh air in microbiome science: shallow shotgun metagenomics for a reliable disentangling of microbial ecosystems [0.03%]
微生物组学研究中的新气象——低深度鸟枪法宏基因组揭示可靠的微生物生态系统组成
Gabriele Andrea Lugli,Marco Ventura
Gabriele Andrea Lugli
Next-generation sequencing technologies allow accomplishing massive DNA sequencing, uncovering the microbial composition of many different ecological niches. However, the various strategies developed to profile microbiomes make it challengi...
The Integrated Probiotic Database: a genomic compendium of bifidobacterial health-promoting strains [0.03%]
集成式益生菌数据库——两歧双歧杆菌健康促进菌株的基因组汇编
Chiara Tarracchini,Martina Viglioli,Gabriele Andrea Lugli et al.
Chiara Tarracchini et al.
Background: The World Health Organization defines probiotics as "live microorganisms, which when administered in adequate amounts confer a health benefit on the host". In this framework, probiotic strains should be regarded as safe for huma...
Ronan Strain,Catherine Stanton,R Paul Ross
Ronan Strain
Intricate interactions among commensal bacteria, dietary substrates and immune responses are central to defining microbiome community composition, which plays a key role in preventing enteric pathogen infection, a dynamic phenomenon referre...
Giovanni Marasco,Cesare Cremon,Maria Raffaella Barbaro et al.
Giovanni Marasco et al.
Irritable bowel syndrome (IBS) affects approximately one tenth of the general population and is characterized by abdominal pain associated with abnormalities in bowel habits. Visceral hypersensitivity, abnormal intestinal motor function, mu...
The human microbiome project at ten years - some critical comments and reflections on "our third genome", the human virome [0.03%]
人类微生物组计划十周年——对“我们的第三种基因组”和人类病毒组的批判性评论与思考
Harald Brüssow
Harald Brüssow
The Human Microbiome Project (HMP) has raised great expectations claiming the far-reaching influence of the microbiome on human health and disease ranging from obesity and malnutrition to effects going well beyond the gut. So far, with the ...
Production of a selective antibacterial fatty acid against Staphylococcus aureus by Bifidobacterium strains [0.03%]
利用双歧杆菌菌株生产抗金黄色葡萄球菌的脂肪酸抗菌物质
Hiroshi Kikukawa,Toshihiro Nagao,Mitsuki Ota et al.
Hiroshi Kikukawa et al.
Aims: C16 monounsaturated fatty acid (C16:1) show antibacterial activity against Staphylococcus aureus, a pathogen associated with various diseases such as atopic dermatitis and bacteremia, while the compound does not exhibit antibacterial ...
Gregor Reid
Gregor Reid
Despite multiple advances in medicine, the management of urinary tract infections (UTIs) in women has remained stalled for decades. To prevent the development of symptomatic recurrences, low-dose antibiotics are the mainstay, while alternat...