Modeling microbiota-associated human diseases: from minimal models to complex systems [0.03%]
从简约模型到复杂系统：模拟与微生物群相关的疾病
Doriane Aguanno,Amira Metwaly,Olivia I Coleman et al.
Doriane Aguanno et al.
Alterations in the intestinal microbiota are associated with various human diseases of the digestive system, including obesity and its associated metabolic diseases, inflammatory bowel diseases (IBD), and colorectal cancer (CRC). All three ...
Distribution, inducibility, and characteristics of Latilactobacillus curvatus temperate phages [0.03%]
乳酸片球菌温和噬菌体的分布、诱生及特性分析
Conrad L Ambros,Matthias A Ehrmann
Conrad L Ambros
Aim: Temperate phages are known to heavily impact the growth of their host, be it in a positive way, e.g., when beneficial genes are provided by the phage, or negatively when lysis occurs after prophage induction. This study provides an in-...
Paenibacillus larvae and their phages; a community science approach to discovery and initial testing of prophylactic phage cocktails against American Foulbrood in New Zealand [0.03%]
_paenibacillus larvae及其噬菌体；一种针对美国美洲幼虫病的预防性噬菌体鸡尾酒的发现和初步测试的公民科学方法_
Danielle N Kok,Diana Zhou,Philippos K Tsourkas et al.
Danielle N Kok et al.
Background: American foulbrood (AFB) is a devastating disease of the European honey bee (Apis mellifera) and is found throughout the world. AFB is caused by the bacterium Paenibacillus larvae (P. larvae). Treatment with antibiotics is stric...
Julija Mezhyrova,Janosch Martin,Clara Börnsen et al.
Julija Mezhyrova et al.
Background: The peptide MS2-L represents toxins of the ssRNA Leviviridae phage family and consists of a predicted N-terminal soluble domain followed by a transmembrane domain. MS2-L mediates bacterial cell lysis through the formation of lar...
Ryuta Murakami,Keisuke Yoshida,Mikiyasu Sakanaka et al.
Ryuta Murakami et al.
Aim: Bifidobacteria benefit host health and homeostasis by breaking down diet- and host-derived carbohydrates to produce organic acids in the intestine. However, the sugar utilization preference of bifidobacterial species is poorly understo...
Microbiota-gut-brain axis and ketogenic diet: how close are we to tackling epilepsy? [0.03%]
微生物-肠道-大脑轴和生酮饮食：我们距离攻克癫痫还有多远？
Mariachiara Mengoli,Gabriele Conti,Marco Fabbrini et al.
Mariachiara Mengoli et al.
The microbiota-gut-brain axis refers to the intricate bidirectional communication between commensal microorganisms residing in the digestive tract and the central nervous system, along neuroendocrine, metabolic, immune, and inflammatory pat...
Assessing the impact of pregnancy and birth factors on the maternal and infant microbiota [0.03%]
评估妊娠和分娩因素对母体和婴儿微生物群的影响
Kait F Al,Laura Allen,Samantha Bedell et al.
Kait F Al et al.
Background: The microbiota acquired at birth is known to play an intimate role in later life health and disease and has been shown to be affected by the mode of birth. There has been recent interest in microbiota correction by maternal vagi...
Lytic bacteriophages affect the population dynamics of multi-strain microbial communities [0.03%]
裂解细菌噬菌体影响多谱系微生物种群的动态变化
Maciej Spus,Yohanes Raditya Wardhana,Judith C M Wolkers-Rooijackers et al.
Maciej Spus et al.
Background: Lytic bacteriophages infect and lyse bacteria and, as a by-product, may affect diversity in microbial communities through selective predation on abundant bacterial strains. We used a complex dairy starter named Ur to investigate...
Alyssa Gutierrez,Brenton Pucket,Melinda A Engevik
Alyssa Gutierrez
Bifidobacterium species are integral members of the human gut microbiota and these microbes have significant interactions with the intestinal mucus layer. This review delves into Bifidobacterium-mucus dynamics, shedding light on the multifa...
Evolved distal tail protein of skunaviruses facilitates adsorption to exopolysaccharide-encoding lactococci [0.03%]
进化后的末端尾部蛋白通过与产生胞外多糖的乳酸菌结合促进skunavirus吸附
Anne M Millen,Damian Magill,Dennis Romero et al.
Anne M Millen et al.
Aim: Lactococcal skunaviruses are diverse and problematic in the industrial dairy environment. Host recognition involves the specific interaction of phage-encoded proteins with saccharidic host cell surface structures. Lactococcal plasmid p...