A pilot study to disentangle the infant gut microbiota composition and identification of bacteria correlates with high fat mass [0.03%]
婴儿肠道菌群组成试点研究及与高脂肪量相关细菌的鉴定
Leonardo Mancabelli,Christian Milani,Federico Fontana et al.
Leonardo Mancabelli et al.
Background: At birth, the human intestine is colonized by a complex community of microorganisms known as gut microbiota. These complex microbial communities that inhabit the gut microbiota are thought to play a key role in maintaining host ...
Sara Roggiani,Mariachiara Mengoli,Gabriele Conti et al.
Sara Roggiani et al.
Although research on the role of the gut microbiota (GM) in human health has sharply increased in recent years, what a "healthy" gut microbiota is and how it responds to major stressors is still difficult to establish. In particular, antica...
A pilot study of dietary fibres on pathogen growth in an ex vivo colonic model reveals their potential ability to limit vancomycin-resistant Enterococcus expansion [0.03%]
膳食纤维对体外结肠模型中病原菌生长的影响研究显示其限制万古霉素耐药粪肠球菌扩增的潜力
Ronan Strain,Tam T T Tran,Susan Mills et al.
Ronan Strain et al.
Aim: Dietary fibre is important for shaping gut microbiota. The aim of this pilot study was to investigate the impact of dietary fibres on pathogen performance in the presence of gut microbiota. Methods: In an ex vivo gut model, pooled faec...
Free lipoproteins from Bifidobacterium longum alleviate osteoarthritis through modulation of the gut microbiome [0.03%]
长双歧杆菌自由脂蛋白通过调节肠道菌群缓解骨关节炎
Famara Sane,Frank Piva,Marie-Bénédicte Romond
Famara Sane
Aim: The "gut-joint" axis is suspected to be involved in the pathophysiology of osteoarthritis (OA). The present study aims at investigating the potential of lipoproteins (Lpps) secreted by Bifidobacterium longum to alleviate OA progression...
The possible role of gut microbiota dysbiosis in the pathophysiology of delirium in older persons [0.03%]
肠道菌群紊乱在老年人谵妄发病机制中的可能作用
Andrea Ticinesi,Alberto Parise,Antonio Nouvenne et al.
Andrea Ticinesi et al.
Delirium is a clinical syndrome characterized by an acute change in attention, awareness and cognition with fluctuating course, frequently observed in older patients during hospitalization for acute medical illness or after surgery. Its pat...
A simple method that enhances minority species detection in the microbiota: 16S metagenome-DRIP (Deeper Resolution using an Inhibitory Primer) [0.03%]
一种增强微生物组中稀有种检测的简单方法：采用抑制引物的16S元基因组DRIP（深层分辨率）法
Aruto Nakajima,Keisuke Yoshida,Aina Gotoh et al.
Aruto Nakajima et al.
Aim: 16S rRNA gene-based microbiota analyses (16S metagenomes) using next-generation sequencing (NGS) technologies are widely used to examine the microbial community composition in environmental samples. However, the sequencing capacity of ...
(Poly)phenolic compounds and gut microbiome: new opportunities for personalized nutrition [0.03%]
（poly）酚类化合物与肠道微生物组：个性化营养的新机遇
Luca Narduzzi,Vicente Agulló,Claudia Favari et al.
Luca Narduzzi et al.
For decades, (poly)phenols have been linked to cardiometabolic health, but population heterogeneity limits their apparent efficacy and the development of tailored, practical protocols in dietary interventions. This heterogeneity is likely d...
Lactobacillus, glycans and drivers of health in the vaginal microbiome [0.03%]
乳酸菌、糖类和阴道微生物组中影响健康的驱动因素
Rosemary Sanozky-Dawes,Rodolphe Barrangou
Rosemary Sanozky-Dawes
A microbiome consists of microbes and their genomes, encompassing bacteria, viruses, fungi, protozoa, archaea, and eukaryotes. These elements interact dynamically in the specific environment in which they reside and evolve. In the past deca...
Marta Selma-Royo,Joaquim Calvo-Lerma,Christine Bäuerl et al.
Marta Selma-Royo et al.
Human milk (HM) is the gold standard for infant nutrition during the first months of life. Beyond its nutritional components, its complex bioactive composition includes microorganisms, their metabolites, and oligosaccharides, which also con...
The evolution of bacterial genome assemblies - where do we need to go next? [0.03%]
细菌基因组组装的发展历程——接下来我们该如何前行？
Eric Altermann,Halina E Tegetmeyer,Ryan M Chanyi
Eric Altermann
Genome sequencing has fundamentally changed our ability to decipher and understand the genetic blueprint of life and how it changes over time in response to environmental and evolutionary pressures. The pace of sequencing is still increasin...