Assimilation of arabinogalactan side chains with novel 3- O-β-L-arabinopyranosyl-α-L-arabinofuranosidase in Bifidobacterium pseudocatenulatum [0.03%]
假链状双歧杆菌新型侧向阿拉伯糖基转移酶的作用机制研究
Yuki Sasaki,Makoto Yanagita,Mimika Hashiguchi et al.
Yuki Sasaki et al.
Aim: Dietary plant fibers affect gut microbiota composition; however, the underlying microbial degradation pathways are not fully understood. We previously discovered 3-O-α-D-galactosyl-α-L-arabinofuranosidase (GAfase), a glycoside hydrol...
Study of the binding of ΔFN3.1 fragments of the Bifidobacterium longum GT15 with TNFα and prevalence of domain-containing proteins in groups of bacteria of the human gut microbiota [0.03%]
ΔFN3.1片段与TNFα的结合及人类肠道菌群各细菌组中含结构域蛋白流行率的研究
Maria G Alekseeva,Ilya N Dyakov,Kristina K Bushkova et al.
Maria G Alekseeva et al.
Aim: This study is mainly devoted to determining the ability of ∆FN3.1 protein fragments of Bifidobacterium (B.) longum subsp. longum GT15, namely two FN3 domains (2D FN3) and a C-terminal domain (CD FN3), to bind to tumor necrosis factor-...
Marco Ventura,Douwe van Sinderen,Francesca Turroni
Marco Ventura
The human gut microbiota is believed to be responsible for multiple health-impacting host effects. The influence of gut microorganisms on the human host begins immediately after birth, having long-lasting health effects, while the gut micro...
Probiotic colonization dynamics after oral consumption of VSL#3® by antibiotic-treated mice [0.03%]
接受VSL#3~(®)的抗生素处理的小鼠的肠道菌群定植动力学
Casey Theriot,Rajani Thanissery,Sarah O&#x;Flaherty et al.
Casey Theriot et al.
Background: The ability of probiotic strains to provide health benefits to the host partially hinges on the survival of gastrointestinal passage and temporary colonization of the digestive tract. This study aims to investigate the colonizat...
Impact of intrapartum antibiotics on the developing microbiota: a review [0.03%]
产时使用抗生素对微生物菌群发育的影响：综述式研究
Silvia Arboleya,Silvia Saturio,Miguel Gueimonde
Silvia Arboleya
The perinatal period sets the basis for the later physiological and immune homeostasis of the individual, with the intestinal microbiota being an important contributor to driving this homeostasis development. Therefore, the initial establis...
The gut-immune-brain axis in neurodevelopment and neurological disorders [0.03%]
肠-免疫-脑轴在神经发育和神经系统疾病中的作用
John Chulhoon Park,Sin-Hyeog Im
John Chulhoon Park
The gut-brain axis is gaining momentum as an interdisciplinary field addressing how intestinal microbes influence the central nervous system (CNS). Studies using powerful tools, including germ-free, antibiotic-fed, and fecal microbiota tran...
Identification of novel genera and subcluster classifications for mycobacteriophages [0.03%]
鉴定新型菌属和分组分类的结核分支杆菌噬菌体
Laura M O&#x;Connell,Colin Buttimer,Francesca Bottacini et al.
Laura M O&#x;Connell et al.
Aim: To identify novel genera amongst mycobacteriophages (MP) and verify a hypothesised correlation between the taxonomy set by the International Committee on Taxonomy of Viruses (ICTV) and the National Centre for Biotechnology Information ...
Giorgia Procaccianti,Sara Roggiani,Gabriele Conti et al.
Giorgia Procaccianti et al.
The gut microbiome has received a crescendo of attention in recent years due to myriad influences on human pathophysiology, including cancer. Anticancer therapy research is constantly looking for new hints to improve response to therapy whi...
Substrate recognition mode of a glycoside hydrolase family 42 β-galactosidase from Bifidobacterium longum subspecies infantis (Bi Bga42A) revealed by crystallographic and mutational analyses [0.03%]
通过晶体学和突变分析揭示的婴儿长双歧杆菌（Bi Bga42A）家族42β-半乳糖苷酶的底物识别模式
Aina Gotoh,Masafumi Hidaka,Haruko Sakurama et al.
Aina Gotoh et al.
Aim: Bifidobacterium longum subsp. infantis uses a glycoside hydrolase (GH) family 42 β-galactosidase (BiBga42A) for hydrolyzing lacto-N-tetraose (LNT), which is the most abundant core structure of human milk oligosaccharides (HMOs). As su...
Microbial interactions and the homeostasis of the gut microbiome: the role of Bifidobacterium [0.03%]
微生物互作与肠道微生态稳态：双歧杆菌的作用
Alberto J M Martin,Kineret Serebrinsky-Duek,Erick Riquelme et al.
Alberto J M Martin et al.
The human gut is home to trillions of microorganisms that influence several aspects of our health. This dense microbial community targets almost all dietary polysaccharides and releases multiple metabolites, some of which have physiological...