The human intestinal bacterium Eggerthella lenta influences gut metabolomes in gnotobiotic mice [0.03%]
肠道菌Eggerthella lenta影响无菌鼠的肠代谢物组成
Alina Viehof,Sven-Bastiaan Haange,Theresa Streidl et al.
Alina Viehof et al.
The intestinal microbiota and its metabolites are known to influence host metabolic health. However, little is known about the role of specific microbes. In this work, we used the minimal consortium Oligo-Mouse-Microbiota (OMM12) to study t...
Bifidobacterium longum subsp. infantis regulates Th1/Th2 balance through the JAK-STAT pathway in growing mice [0.03%]
婴儿双歧杆菌通过JAK-STAT途径调节生长小鼠的Th1/Th2平衡
Mengfan Ding,Bowen Li,Haiqin Chen et al.
Mengfan Ding et al.
Objectives: Bifidobacterium longum subsp. infantis is a dominant bacterium in infant gut, which plays a critical role in maintaining the health and development of infants. This study investigated the abilities of eight different strains of ...
RapidAIM 2.0: a high-throughput assay to study functional response of human gut microbiome to xenobiotics [0.03%]
快速AIM 2.0：一种高通量测定方法，用于研究人体肠道微生物组对外来化合物的功能反应
Leyuan Li,Janice Mayne,Adrian Beltran et al.
Leyuan Li et al.
Aim: Our gut microbiome has its own functionalities which can be modulated by various xenobiotic and biotic components. The development and application of a high-throughput functional screening approach of individual gut microbiomes acceler...
Methodological recommendations for human microbiota-gut-brain axis research [0.03%]
人类微生物群-肠-脑轴研究的方法学建议
Yangwenshan Ou,Clara Belzer,Hauke Smidt et al.
Yangwenshan Ou et al.
Observational studies have determined numerous correlations between sequence-based gut microbiota data and human mental traits. However, these associations are often inconsistent across studies. This inconsistency is one of the reasons that...
The role of microbiota in tumorigenesis, progression and treatment of bladder cancer [0.03%]
微生物群在膀胱癌发生、发展和治疗中的作用
Zijing Peng,Jingming Zhuang,Bing Shen
Zijing Peng
For decades, the urinary system was regarded as a sterile environment due to the absence of any bacterial growth in clinical standard urine cultures from healthy individuals. However, a diverse array of microbes colonizes the urinary system...
Zhenming Xiao,Miaomiao Pan,Xinyao Li et al.
Zhenming Xiao et al.
The composition and function of the gut microbiota constantly influence health. Disruptions in this delicate balance, termed gut microbiota dysbiosis, have been implicated in various adverse health events. As the largest global epidemic sin...
Fungal and bacterial gut microbiota differ between Clostridioides difficile colonization and infection [0.03%]
艰难梭菌定植与感染的粪 fungal 和 bacterial 菌群有差异
Jannie G E Henderickx,Monique J T Crobach,Elisabeth M Terveer et al.
Jannie G E Henderickx et al.
Aim: The bacterial microbiota is well-recognized for its role in Clostridioides difficile colonization and infection, while fungi and yeasts remain understudied. The aim of this study was to analyze the predictive value of the mycobiota and...
Pathways linking microbiota-gut-brain axis with neuroinflammatory mechanisms in Alzheimer's pathophysiology [0.03%]
微生物群-肠道-大脑轴与阿尔茨海默病神经炎症机制的联系路径
Nathaniel Hochuli,Saurabh Kadyan,Gwoncheol Park et al.
Nathaniel Hochuli et al.
Disturbances in the local and peripheral immune systems are closely linked to a wide range of diseases. In the context of neurodegenerative disorders such as Alzheimer's disease (AD), inflammation plays a crucial role, often appearing as a ...
Screening competition and cross-feeding interactions during utilization of human milk oligosaccharides by gut microbes [0.03%]
肠道微生物在利用人类母乳低聚糖过程中的筛选竞争和交叉喂养相互作用
Romina Díaz,Daniel Garrido
Romina Díaz
Background: The infant gut microbiome is a complex community that influences short- and long-term health. Its assembly and composition are governed by variables such as the feeding type. Breast milk provides infants an important supply of h...