Cardiovascular disease burden in patients with urological cancers: The new discipline of uro-cardio-oncology [0.03%]
泌尿系统癌症患者的心血管疾病负担：新兴的泌尿-心血管-肿瘤学学科
Yi Zheng,Ying Liu,Ziliang Chen et al.
Yi Zheng et al.
Cancer remains a major cause of mortality worldwide, and urological cancers are the most common cancers among men. Several therapeutic agents have been used to treat urological cancer, leading to improved survival for patients. However, thi...
18F-FDG PET/CT findings of paratesticular alveolar rhabdomyosarcoma [0.03%]
18F-FDG PET/CT对阴囊横纹肌肉瘤的影像表现
Xueqi Chen,Jiayin Shou,Shanshi Li et al.
Xueqi Chen et al.
Rhabdomyosarcoma (RMS) originates from primitive mesenchymal cells and is the most common soft tissue tumor in childhood. 18F-fluoro-deoxyglucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) has been reported to be ...
Case Reports
Cancer innovation. 2024 Apr 8;3(2):e121. DOI:10.1002/cai2.121 2024
Improvement of histone deacetylase inhibitor efficacy by SN38 through TWIST1 suppression in synovial sarcoma [0.03%]
SN38通过抑制TWIST1增强组蛋白去乙酰化酶抑制剂在滑膜肉瘤中的疗效
Satoru Sasagawa,Jun Kumai,Toru Wakamatsu et al.
Satoru Sasagawa et al.
Background: Synovial sarcoma (SS) is an SS18-SSX fusion gene-driven soft tissue sarcoma with mesenchymal characteristics, associated with a poor prognosis due to frequent metastasis to a distant organ, such as the lung. H...
Xuesong Li,Zheng Mo,Zhuo Yu
Xuesong Li
von Hippel-Lindau (VHL) disease is a rare autosomal dominant multiorgan disease characterized by several benign and malignant tumors rich in vascular, as well as cysts in other organs. A great clinical treatment strategy is significantly wa...
Case Reports
Cancer innovation. 2023 Sep 20;3(2):e94. DOI:10.1002/cai2.94 2023
Advances in the role of circulating tumor cell heterogeneity in metastatic small cell lung cancer [0.03%]
循环肿瘤细胞异质性在小细胞肺癌转移中的作用进展
Qunxia Wang,Li-Ming Tan
Qunxia Wang
Small cell lung cancer (SCLC), a highly aggressive malignancy, is rapidly at an extensive stage once diagnosed and is one of the leading causes of death from malignancy. In the past decade, the treatment of SCLC has largely remained unchang...
ALKBH5 gene polymorphisms and risk of neuroblastoma in Chinese children from Jiangsu Province [0.03%]
江苏儿童神经母细胞瘤发病与ALKBH5基因多态性的关系研究
Qian Guan,Xinxin Zhang,Jiabin Liu et al.
Qian Guan et al.
Background: Neuroblastoma is one of the most common extracranial malignant solid tumors in children. AlkB homolog 5 (ALKBH5) is an RNA N6-methyladenosine (m6A) demethylase that plays a critical role in tumorigenesis and d...
Na Sun,Cheng Wang,Pingping Gao et al.
Na Sun et al.
SRY-box transcription factor 30 (SOX30) participates in tumor cell apoptosis in lung cancer. The occurrence of somatic SOX30 mutations, the expression signature of SOX30 in normal and cancer tissues, the correlation of SOX30 with immune cel...
Shilpa Malakar,Emmanuel Nuah Gontor,Moses Y Dugbaye et al.
Shilpa Malakar et al.
Biosimilars are biological drugs created from living organisms or that contain living components. They share an identical amino-acid sequence and immunogenicity. These drugs are considered to be cost-effective and are utilized in the treatm...
Mutations in the DNA polymerase binding pathway affect the immune microenvironment of patients with small-cell lung cancer and enhance the efficacy of platinum-based chemotherapy [0.03%]
DNA聚合酶结合途径的突变影响小细胞肺癌患者的免疫微环境并增强基于铂类的化疗效果
Anqi Lin,Weiming Mou,Lingxuan Zhu et al.
Anqi Lin et al.
Background: Small-cell lung cancer (SCLC) is characterized by its high malignancy and is associated with a poor prognosis. In the early stages of the disease, platinum-based chemotherapy is the recommended first-line trea...
Added value of molecular karyotype in childhood acute lymphoblastic leukemia [0.03%]
分子核型在儿童急性淋巴细胞白血病中的附加价值
Margaux Camuset,Baptiste Le Calvez,Olivier Theisen et al.
Margaux Camuset et al.
Background: Thanks to an improved therapeutic regimen in childhood B-cell precursor acute lymphoblastic leukemia (BCP-ALL), 5 year-overall survival now exceeds 90%. Unfortunately, the 25% of children who relapse have an i...