Role of gut microbiota in ischemic stroke: A narrative review of human and animal studies [0.03%]
肠道菌群在缺血性卒中中的作用：人类和动物研究的叙述性回顾
Guangtang Chen,Xiaolin Du,Junshuan Cui et al.
Guangtang Chen et al.
The high incidence, mortality, and disability associated with ischemic stroke pose a significant threat to human health. The intestinal microbiota significantly influences the onset, progression, and prognosis of ischemic stroke. Gut flora ...
Puyuan Wen,Chao Ren
Puyuan Wen
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder globally, significantly affecting the quality of life of affected individuals. Systemic drug delivery to the brain is inefficient because of first-pass metabol...
Glutamate and excitotoxicity in central nervous system disorders: ionotropic glutamate receptors as a target for neuroprotection [0.03%]
中枢神经系统疾病中的谷氨酸和兴奋毒性：离子型谷氨酸受体作为神经保护作用的靶点
Jorge Y Magdaleno Roman,Christian Chapa González
Jorge Y Magdaleno Roman
Recent advances in neuroscience have illuminated the central role of glutamate dysregulation in various neurological disorders. The glutamatergic system has emerged as a central player in the pathophysiology of various neurological disorder...
Novel therapeutic strategies and common mechanisms of neurodegenerative diseases [0.03%]
新颖的治疗策略及神经退行性疾病的共性机制研究
Šárka Lehtonen,Jukka Jolkkonen
Šárka Lehtonen
Aishika Datta,Soumya Akundi,Kaveri Wagh et al.
Aishika Datta et al.
Stroke, a leading cause of mortality and morbidity worldwide, is a complex cerebrovascular disease. Stroke risk factors are diverse, encompassing age, sex, and ethnicity. Comorbid conditions, including hypertension, hyperglycemia, hyperlipi...
The dynamic relationship of brain-derived neurotrophic factor and oxytocin: Introducing the concept of neurosocial plasticity [0.03%]
脑源性神经营养因子和催产素的动态关系：引入神经社交可塑性的概念
Jamshid Faraji,Gerlinde A S Metz
Jamshid Faraji
The human brain functions as a highly integrated system. Interconnected cellular and molecular networks within this system process sensory information, cognitive functions, and motor responses. The brain also exhibits a remarkable potential...
Xiaoxuan Zhang,Mengmeng Zhong,Yang Li et al.
Xiaoxuan Zhang et al.
Oral microbiota is the second largest microbial colony in the body and forms a complex ecological community that influences oral and brain health. Impaired homeostasis of the oral microbiota can lead to pathological changes, resulting in ce...
Advancing neuroprotection and atherosclerosis prevention through familial hypercholesterolemia management: Analyzing comorbidity burden with stroke, coronary heart disease, hypertension, and diabetes [0.03%]
通过家族性高胆固醇管理来推进神经保护和动脉粥样硬化预防：分析与卒中、冠心病、高血压和糖尿病共病负担
Jingjia Wang,Sicong Liu,Ming Zhang et al.
Jingjia Wang et al.
Background: Despite the World Health Organization's prioritization of familial hypercholesterolemia (FH), its global diagnostic rate remains critically low, leading to inadequate treatment and control, thereby increasing ...
Unravelling the nexus of stroke and dementia: Deciphering the role of secondary neurodegeneration in orchestrating cognitive decline [0.03%]
解开卒中与痴呆之间的联系：解密继发性神经退行性病变在认知衰退中的作用
Shannon M Stuckey,Rebecca J Hood,Lin Kooi Ong et al.
Shannon M Stuckey et al.
Stroke is the leading cause of acquired disability. The development of acute ischemic stroke treatments, such as mechanical thrombectomy and tissue plasminogen activator, has resulted in more patients surviving the initial insult. However, ...
Pilot functional magnetic resonance imaging study of clemastine-aided functional recovery on a mouse model of demyelination [0.03%]
盐酸赛庚啶辅助脱髓鞘小鼠模型行为学恢复的初步功能磁共振成像研究
Ander Egimendia,Irati L de la Pisa,Daniel Padro et al.
Ander Egimendia et al.
Background: Multiple sclerosis (MS) is a chronic demyelinating disease characterized by autoimmune attacks on myelin sheaths. Its deleterious effects may be reversed by remyelination, a process that restores the integrity...