Spinal cord transection repair occurs when Nestin+ cells differentiate into neurons within a taxol-collagen-enhanced microenvironment in mice [0.03%]
小鼠脊髓损伤后Nestin阳性细胞在紫杉醇-胶原促进微环境中分化成神经元实现脊髓修复
Caixia Fan,He Jiang,Junyan Yan et al.
Caixia Fan et al.
Background: Previous studies have shown that taxol promotes axon regeneration in nerve repair, but fails to bridge the two ends of a completely transected spinal cord. Our prior in vitro research revealed that taxol, a mi...
Tobiloba S Olajide
Tobiloba S Olajide
Glial cells, alongside neurons, are the major cells of the central nervous system. More than just supporting neurons, glial cells are vital in central nervous system homeostasis and actively shape neurodegenerative disease mechanisms. They ...
Therapeutic potential of stem cells in pediatric neurology: Insights from clinical trials [0.03%]
干细胞在儿科神经病学中的治疗潜力：来自临床试验的启示
Daniel Bou Najm,Saada Alame
Daniel Bou Najm
Pediatric neurological disorders comprise diverse conditions that impair nervous system function in children and contribute substantially to global disease burden. Stem cell therapy has become a promising treatment in neurology due to the c...
Bibliometric analysis and core target identification of network pharmacology on neuroinflammation in central nervous system disorders: Trends, collaborations, and future directions [0.03%]
中枢神经系统疾病中神经炎症的网络药理学文献计量分析及核心靶点识别：趋势、合作和未来方向
Yifeng Zhang,Shuai Hou,Jian Li et al.
Yifeng Zhang et al.
Neuroinflammation is increasingly recognized as a critical driver of central nervous system (CNS) disorders, and network pharmacology has emerged as a promising approach to elucidate its complex mechanisms and therapeutic strategies. This s...
A holistic view on disease-modifying aspects, comorbidities, and contemporary neuroprotective approaches [0.03%]
从疾病修正作用、共病以及当代神经保护性方法等方面对肌萎缩侧索硬化进行综合性研究观点
Piotr Walczak,Shen Li,Xunming Ji et al.
Piotr Walczak et al.
The effects and mechanisms of stem cells and exosomes on neurological function protection and recovery after ischemic stroke [0.03%]
缺血性卒中后神经功能保护和修复的干细胞和外泌体的作用及机制研究
Weihong Du,Yuxian He,Liangchen Li et al.
Weihong Du et al.
Stroke can cause motor sensory impairment and cognitive impairment. Current interventions focus on thrombolysis or thrombectomy in the acute stage, and promoting the recovery of neurological function during the chronic stage. However, so fa...
A comprehensive review on adaptive plasticity and recovery mechanisms post-acquired brain injury [0.03%]
获得性脑损伤后的自适应可塑性和恢复机制的全面综述
Ravi Kumar Rajan
Ravi Kumar Rajan
Adaptive plasticity, the brain's ability to reorganize and form new neural connections after injury, is crucial for recovery following acquired brain injury (ABI). This process involves axonal sprouting, dendritic remodeling, and neurogenes...
Shuzhen Guo,Gen Hamanaka,Fang Zhang et al.
Shuzhen Guo et al.
Background: Aging affects almost all aspects of central nervous system (CNS) function, including the blood-brain barrier (BBB). Here, we use cell culture models to ask whether senescence, a cellular feature of aging, alte...
Role of astrocyte in neuroinflammation-induced loss in neuroplasticity and subsequent onset of depression: A systematic review [0.03%]
星形胶质细胞在神经炎症诱导的神经可塑性丧失及随后抑郁症发病中的作用：系统评价研究
Gaurav Singhal,Saurabh Singhal,Bernhard T Baune
Gaurav Singhal
Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities. While microglia have traditionally been the focus...
How pandemics reshape our brain: Common links and targets between long-haul COVID-19, myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), oxidative stress, and neurodegeneration [0.03%]
大流行如何重塑我们的大脑：长期新冠、肌痛性脑脊髓炎/慢性疲劳综合征（ME/CFS）、氧化应激和神经退行性疾病之间的共同联系和作用靶点
Mary E Herman
Mary E Herman
Fatiguing syndromes affect millions of patients in the United States and globally, but are grossly underserved in the clinic and in the contemplative design of basic research.Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a ...