ScRNAPip: A systematic and dynamic pipeline for single-cell RNA sequencing analysis [0.03%]
单细胞RNA测序分析的系统动态流程：ScRNAPip
Limin Xu,Jing Zhang,Yiqian He et al.
Limin Xu et al.
With the advancement of sequencing technology, cell separation, and whole-genome amplification techniques, single cell technology for genome sequencing is emerging gradually. In comparison to traditional genome sequencing at the multi-cellu...
Distinct responses of airborne abundant and rare microbial communities to atmospheric changes associated with Chinese New Year [0.03%]
与中国农历新年相关的大气变化对空气中丰富和稀有微生物群落的影响不同的响应
Hu Li,You-Wei Hong,Meng-Ke Gao et al.
Hu Li et al.
Airborne microorganisms, including pathogens, would change with surrounding environments and become issues of global concern due to their threats to human health. Microbial communities typically contain a few abundant but many rare species....
Melatonin supplementation protects against traumatic colon injury by regulating SERPINA3N protein expression [0.03%]
褪黑素通过调节SERPINA3N蛋白表达对创伤性结肠损伤的保护作用研究
Bo Cao,Jing-Wang Gao,Qing-Peng Zhang et al.
Bo Cao et al.
Traumatic colon injury (TCI) is a typical injury with high mortality. Prolongation of the intervention time window is a potentially useful approach to improving the outcomes of TCI casualties. This study aimed to identify the pathological m...
Host selection tendency of key microbiota in arid desert lichen crusts [0.03%]
干旱沙漠地衣壳中关键微生物群的宿主选择倾向性研究
Ting-Ting Zhang,Martin Grube,Xin-Li Wei
Ting-Ting Zhang
Lichen genus Endocarpon in biological soil crust form was chosen as a model to investigate the bacterial communities for the first time across four vertically distinct strata. Key bacterial microbiota in lichen thallus were discovered, whic...
MIST: A microbial identification and source tracking system for next-generation sequencing data [0.03%]
基于下一代测序数据的微生物识别及来源追踪系统(MIST)
Minghui Song,Chang Han,Linmeng Liu et al.
Minghui Song et al.
The Professional Committee of Microbiology of the National Pharmacopoeia Commission organized the drafting of the Technical Guidelines for Microbial Whole Genome Sequencing (WGS), aiming to standardize the method process and technical indic...
MetaSVs: A pipeline combining long and short reads for analysis and visualization of structural variants in metagenomes [0.03%]
元基因组结构变异的分析和可视化管道 MetaSVs：结合长读段与短读段数据进行元基因组中结构变异的分析及可视化
Yuejuan Li,Jiabao Cao,Jun Wang
Yuejuan Li
Structural variants (SVs, including large-scale insertions, deletions, inversions, and translocations) significantly impact the functions of genes in the microbial genome, and SVs in the microbiome are associated with diverse biological pro...
cisDynet: An integrated platform for modeling gene-regulatory dynamics and networks [0.03%]
cisDynet：一种用于构建基因调控动态和网络的集成平台
Tao Zhu,Xinkai Zhou,Yuxin You et al.
Tao Zhu et al.
Chromatin accessibility sequencing has been widely used for uncovering genetic regulatory mechanisms and inferring gene regulatory networks. However, effectively integrating large-scale chromatin accessibility datasets has posed a significa...
Intraspecific difference of Latilactobacillus sakei in inflammatory bowel diseases: Insights into potential mechanisms through comparative genomics and metabolomics analyses [0.03%]
炎症性肠病中Latilactobacillus sakei的种内差异：通过比较基因组学和代谢组学分析揭示潜在机制的见解
Yaru Liu,Hui Duan,Ying Chen et al.
Yaru Liu et al.
Inflammatory bowel diseases (IBDs) are chronic inflammatory diseases of the gastrointestinal tract that have become a global health burden. Studies have revealed that Latilactobacillus sakei can effectively alleviate various immune diseases...
HPVTIMER: A shiny web application for tumor immune estimation in human papillomavirus-associated cancers [0.03%]
HPV TIMER：一个用于估计与人类乳头瘤病毒相关癌症中肿瘤免疫状况的网页应用程序
Liying Liu,Yanan Xie,Hong Yang et al.
Liying Liu et al.
The tumor immune microenvironment (TIME) is closely associated with tumor formation, particularly linked to the human papillomavirus (HPV), and regulates tumor initiation, proliferation, infiltration, and metastasis. With the rise of immuno...
Taxonomic identification of bile salt hydrolase-encoding lactobacilli: Modulation of the enterohepatic bile acid profile [0.03%]
胆盐水解酶编码乳杆菌的分类鉴定：调节肠肝胆汁酸谱型
Ziwei Song,Shuo Feng,Xingchen Zhou et al.
Ziwei Song et al.
Bile salt hydrolases (BSHs) are enzymes that are essential for the enterohepatic metabolism of bile acids (BAs). BSHs catalyze the production of unconjugated BAs and regulate the homeostasis of BA pool. This study identified Lactobacillus a...