Correction to "Cross-tissue multi-omics analyses reveal the gut microbiota's absence impacts organ morphology, immune homeostasis, bile acid and lipid metabolism" [0.03%]
“多组学分析揭示肠道微生物群的缺失影响器官形态、免疫稳态、胆汁酸和脂质代谢”一文的勘误通知书
[This corrects the article DOI: 10.1002/imt2.272.]. © 2025 The Author(s). iMeta published by John Wiley & Sons Australia, Ltd on behalf of iMeta Science...
Published Erratum
iMeta. 2025 Nov 16;4(6):e70092. DOI:10.1002/imt2.70092 2025
Single-cell spatial transcriptomics reveals potential molecular mechanisms of Abelmoschus manihot (L.) medic in treating diabetic kidney disease [0.03%]
单细胞空间转录组揭示Abelmoschus manihot(L.)Medic治疗糖尿病肾病的潜在分子机制
Chenhua Wu,Haitao Tang,Yihong Yu et al.
Chenhua Wu et al.
A clinical study reported that Abelmoschus manihot (L.) Medic (A. manihot), in the form of Huangkui capsule (HKC), combined with irbesartan (IRB) is an effective therapy for patients with diabetic kidney disease (DKD). The bioactive compone...
A vast stem-progenitor cell pool, richly vascular system, and hybrid ossification drive the daily centimeter-scale elongation of bony antlers [0.03%]
巨大的干细胞池、丰富的血管系统以及杂交骨化驱动鹿角每日厘米级的生长
Hengxing Ba,Shidian He,Hai-Xi Sun et al.
Hengxing Ba et al.
Bone growth and regeneration remain major clinical challenges. Deer antlers, the fastest-growing mammalian bone, regenerate via endochondral ossification and elongate up to 2 cm per day, far surpassing the ~2 cm annual growth of human growt...
A comprehensive benchmarking for spatially resolved transcriptomics clustering methods across variable technologies, organs, and replicates [0.03%]
跨变量技术、器官和重复的全面基准测试空间转录组学聚类方法
Renjie Chen,Yue Yao,Jingyang Qian et al.
Renjie Chen et al.
Spatial clustering is a critical step in the analysis of spatially resolved transcriptomics, serving as the foundation for downstream investigation of tissue heterogeneity. Although numerous computational tools have been developed, systemat...
Nationwide profiling of vaginal microbiota in Chinese women reveals age-dependent shifts and predictive biomarkers for reproductive health [0.03%]
中国女性全国范围内的阴道微生态剖绘揭示年龄相关的改变及生殖健康的预测生物标志物
Cancan Qi,Yingxuan Zhang,Wei Qing et al.
Cancan Qi et al.
The vaginal microbiome is central to reproductive health, yet large-scale studies in East Asian populations remain scarce. Here, we characterized the vaginal microbiota of 6423 Chinese women of reproductive age across 18 provinces and asses...
The interplay between tissue-resident microbiome and host proteins by integrated multi-omics during progression of colorectal adenoma to carcinoma [0.03%]
整合多组学分析结肠腺瘤到结肠癌进展过程中驻留菌群与宿主蛋白的相互作用
Di Wu,An-Jun Wang,De-Chao Bu et al.
Di Wu et al.
The intratumoral microbiome is an emerging hallmark of cancer, yet its multi-kingdom host-microbiome ecosystem in colorectal cancer (CRC) remains poorly characterized. Here, we conducted an integrated analysis using deep shotgun metagenomic...
PhyloSuite v2: The development of an all-in-one, efficient and visualization-oriented suite for molecular dating analysis and other advanced features [0.03%]
PhyloSuite v2:分子年代分析及其他高级功能的一站式高效可视化软件包的开发
Dong Zhao,Tong Ye,Fangluan Gao et al.
Dong Zhao et al.
MCMCtree and r8s are among the most popular molecular dating tools in the current genomic era, but their utility is hampered by steep learning curves, particularly concerning input file formatting, the complexity of fossil calibration setup...
Cultivar-specific preference of bacterial communities and host immune receptor kinase modulate the outcomes of rice-microbiota interactions [0.03%]
水稻品种特异性细菌定植模式及其对微生物刺激的免疫反应调控水稻与根际微生物相互作用结果
Jiwei Xu,Peiyao Hu,Meng Liu et al.
Jiwei Xu et al.
Deciphering how plant-microbiota interactions achieve beneficial outcomes for crops will provide innovative strategies for sustainable agriculture. Here, we dissected rice-microbiota dynamics using a tailored gnotobiotic cultivation system ...
Metagenomics and digital cell modeling facilitate targeted high-throughput sorting of anaerobic hydrogen-producing microorganisms [0.03%]
元基因组学和数字细胞模型促进厌氧产氢微生物的靶向高通量分选
Jianfeng Liu,Wei Xing,Xingyang Zhang et al.
Jianfeng Liu et al.
This study proposes a novel strategy that prioritizes functional recognition, followed by targeted high-throughput sorting, to enable the comprehensive, rapid, and efficient acquisition of target microorganisms. Using metagenomic sequencing...
Genome-wide CRISPR screen reveals an uncharacterized spliceosome regulator as new candidate immunotherapy target [0.03%]
全基因组CRISPR筛选发现一个新的剪接体调节因子并鉴定其成为新的免疫治疗靶点
Tong Shao,Chuanyang Liu,Jingyu Kuang et al.
Tong Shao et al.
Cancer immune evasion is orchestrated by tumor-intrinsic molecular constraints that remain incompletely defined. Here, we performed an in vivo genome-wide clustered regularly interspaced short palindromic repeats (CRISPR) loss-of-function s...